1,273 research outputs found

    Analog circuit fault diagnosis via FOA-LSSVM

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    At present, the research on fault detection and diagnosis technology is very significant to improve the reliability of the equipment, which can greatly improve the safety and efficiency of the equipment. This paper proposes a new fault detection and diagnosis means based on the FOA-LSSVM algorithm. Experimental results demonstrate that the algorithm is effective for the detection and diagnosis of analog circuit faults. In addition, the model also demonstrate good generalization ability

    Non-Invasive and In Situ Characterization of the Degradation of Biomaterial Scaffolds by Volumetric Photoacoustic Microscopy

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    Degradation is among the most important properties of biomaterial scaffolds, which are indispensable for regenerative medicine. The currently used method relies on the measurement of mass loss across different samples and cannot track the degradation of an individual scaffold in situ. Here we report, for the first time, the use of multiscale photoacoustic microscopy to non-invasively monitor the degradation of an individual scaffold. We could observe alterations to the morphology and structure of a scaffold at high spatial resolution and deep penetration, and more significantly, quantify the degradation of an individual scaffold as a function of time, both in vitro and in vivo. In addition, the remodeling of vasculature inside a scaffold can be visualized simultaneously using a dual-wavelength scanning mode in a label-free manner. This optoacoustic method can be used to monitor the degradation of individual scaffolds, offering a new approach to non-invasively analyze and quantify biomaterial–tissue interactions in conjunction with the assessment of in vivo vascular parameters

    Perturbation Theory of Single Particle Spectrum of Antiferromagnetic Mott Insulating States in the Hubbard Models

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    In this work, we present an analytical framework for studying antiferromagnetic (AFM) Mott insulating states in the Hubbard model. We first derive an analytical solution for the single-particle Green's functions in the atomic limit. Within a second-order perturbation approach, we compute the ground state energy and show that the ground state is antiferromagnetically ordered. Then we derive an analytical solution for single-particle Green's functions when effects of the hopping term are considered in the N\'{e}el state. With the analytical solution, we compute and explain various properties of antiferromagnetic Mott insulators observed both experimentally and numerically: i) magnetic blueshift of the Mott gap; ii) spectral functions with features comparable to observations by angle-resolved photoemission spectroscopy on parental compounds of cuprate high TcT_c superconductors. This work comprehends the electronic properties of antiferromagnetic Mott states analytically and provides a foundation for future investigations of doped antiferromagnetic Mott insulators, aiming for the mechanism of cuprates high-TcT_c superconductivity.Comment: 4.5 pages, 2 figure

    Generation of Human Epidermis-Derived Mesenchymal Stem Cell-like Pluripotent Cells and their reprogramming in mouse chimeras

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    Stem cells can be derived from the embryo (embryonic stem cells, ESCs), from adult tissues (adult stem cells, ASCs), and by induction of fibroblasts (induced pluripotent stem cells, iPSs). Ethical problems, immunological rejection, and difficulties in obtaining human tissues limit the use of ESCs in clinical medicine. Induced pluripotent stem cells are difficult to maintain in vitro and carry a greater risk of tumor formation. Furthermore, the complexity of maintenance and propagation is especially difficult in the clinic. Adult stem cells can be isolated from several adult tissues and present the possibility of self-transplantation for the clinical treatment of a variety of human diseases. Recently, several ASCs have been successfully isolated and cultured in vitro, including hematopoietic stem cells (HSCs) , mesenchymal stem cells (MSCs), epidermis stem cells, neural stem cells (NSCs), adipose-derived stem cells (ADSCs), islet stem cells, and germ line stem cells. Human mesenchymal stem cells originate mainly from bone marrow, cord blood, and placenta, but epidermis-derived MSCs have not yet been isolated. We isolated small spindle-shaped cells with strong proliferative potential during the culture of human epidermis cells and designed a medium to isolate and propagate these cells. They resembled MSCs morphologically and demonstrated pluripotency in vivo; thus, we defined these cells as human epidermis-derived mesenchymal stem cell-like pluripotent cells (hEMSCPCs). These hEMSCPCs present a possible new cell resource for tissue engineering and regenerative medicine

    Tetra­aqua­bis­[4-(4H-1,2,4-triazol-4-yl)benzoato-κN 1]copper(II) dihydrate

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    In the title compound, [Cu(C9H6N3O2)2(H2O)4]·2H2O, the CuII atom lies on an inversion center and is six-coordinated by two N atoms from two 4-(1,2,4-triazol-4-yl)benzoate ligands and four water mol­ecules in a distorted octa­hedral geometry. In the crystal, inter­molecular O—H⋯O hydrogen bonds lead to a three-dimensional supra­molecular network. Intra­molecular O—H⋯N hydrogen bonds and π–π inter­actions between the benzene rings and between the benzene and triazole rings [centroid–centroid distances = 3.657 (1) and 3.752 (1) Å] are observed
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