744 research outputs found
Student teamwork: developing virtual support for team projects
In the 21st century team working increasingly requires online cooperative skills as well as more traditional skills associated with face to face team working. Virtual team working differs from face to face team working in a number of respects, such as interpreting the alternatives to visual cues, adapting to synchronous communication, developing trust and cohesion and cultural interpretations. However, co-located student teams working within higher education can only simulate team working as it might be experienced in organisations today. For example, students can learn from their mistakes in a non-threatening environment, colleagues tend to be established friends and assessing teamwork encourages behaviour such as “free-riding”. Using a prototyping approach, which involves students and tutors, a system has been designed to support learners engaged in team working. This system helps students to achieve to their full potential and appreciate issues surrounding virtual teamwork. The Guardian Agent system enables teams to allocate project tasks and agree ground rules for the team according to individuals’ preferences. Results from four cycles of its use are presented, together with modifications arising from iterations of testing. The results show that students find the system useful in preparing for team working, and have encouraged further development of the system
An overview of the cutaneous porphyrias
This is an overview of the cutaneous porphyrias. It is a narrative review based on the published literature and my personal experience; it is not based on a formal systematic search of the literature. The cutaneous porphyrias are a diverse group of conditions due to inherited or acquired enzyme defects in the porphyrin–haem biosynthetic pathway. All the cutaneous porphyrias can have (either as a consequence of the porphyria or as part of the cause of the porphyria) involvement of other organs as well as the skin. The single commonest cutaneous porphyria in most parts of the world is acquired porphyria cutanea tarda, which is usually due to chronic liver disease and liver iron overload. The next most common cutaneous porphyria, erythropoietic protoporphyria, is an inherited disorder in which the accumulation of bile-excreted protoporphyrin can cause gallstones and, rarely, liver disease. Some of the porphyrias that cause blistering (usually bullae) and fragility (clinically and histologically identical to porphyria cutanea tarda) can also be associated with acute neurovisceral porphyria attacks, particularly variegate porphyria and hereditary coproporphyria. Management of porphyria cutanea tarda mainly consists of visible-light photoprotection measures while awaiting the effects of treating the underlying liver disease (if possible) and treatments to reduce serum iron and porphyrin levels. In erythropoietic protoporphyria, the underlying cause can be resolved only with a bone marrow transplant (which is rarely justifiable in this condition), so management consists particularly of visible-light photoprotection and, in some countries, narrowband ultraviolet B phototherapy. Afamelanotide is a promising and newly available treatment for erythropoietic protoporphyria and has been approved in Europe since 2014
Liberty and the individual: the colony asylum in Scotland and England
This paper analyses the buildings, spaces and interiors of Bangour Village public asylum for the insane, near Edinburgh, and compares these with an English asylum, Whalley, near Preston, of similar early-twentieth-century date. The village asylum, which developed from a European tradition of rendering the poor productive through ‘colonisation’, was more enthusiastically and completely adopted in Scotland than in England, perhaps due to differences in asylum culture within the two jurisdictions. ‘Liberty’ and ‘individuality’, in particular, were highly valued within Scottish asylum discourses, arguably shaping material provision for the insane poor from the scale of the buildings to the quality of the furnishings. The English example shows, by contrast, a greater concern with security and hygiene. These two differing interpretations show a degree of flexibility within the internationalized asylum model which is seldom recognized in the literature
Defining a Civil War battlefield: recent archaeological investigations at the Pickett\u27s Mill State Historic Site, Paulding County, Georgia.
Recent investigations at the Pickett\u27s Mill State Historic Site have yielded new insights into the Civil War battle that occurred in May 1864. Military and historical sources have documented that the major battle took place in a ravine, but that skirmishes also occurred in adjacent areas, including a large, open wheat field. Some reports have suggested that Confederate soldiers had forced Union troops out of the ravine into this field where they became exposed. In the summer of 2006 a variety of different archaeological techniques were employed to determine what role the wheat field played in the battle. This paper describes the archaeological techniques that were used and their effectiveness in identifying and recovering military items associated with the battle. Among them, metal detectors proved to be the most effective tool with hundreds of artifacts being recovered from the site
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The archaeology of the military orders: the material culture of holy war
This paper reviews the current state of research into the archaeology of the military orders. It contrasts the advances made by historians and archaeologists, with the latter continuing to focus on the particularism of individual sites, with an emphasis on architectural analyses. Historians have contributed new insights by adopting a supranational approach. This paper argues that archaeologists can build on this by adopting a more problem-oriented, comparative approach. Drawing on examples from frontier and heartland territories, archaeological approaches are subdivided into material investment, material identity and cultural landscapes, to place sites of the military orders within a long-term, multi-scalar contexts. This contributes to a broader social and economic understanding of the orders, who contributed significantly to urbanisation, rural development and trade, and invested in material expressions of their authority and ideology. The paper concludes that more holistic, inter-regional approaches will move the archaeological study of the military orders forward
Characterization of translation products of the polyadenylated RNA of free and membrane-bound polyribosomes of rat forebrain
Diagnostic Strategies for Autosomal Dominant Acute Porphyrias: Retrospective Analysis of 467 Unrelated Patients Referred for Mutational Analysis of the HMBS, CPOX, or PPOX Gene
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Progress in evaluation of radionuclide geochemical information developed by DOE high-level nuclear waste repository site projects. Annual report, October 1984-September 1985. Volume 4
Information pertaining to the potential geochemical behavior of radionuclides at candidate sites for a high-level radioactive waste repository, which is being developed by projects within the Department of Energy (DOE), is being evaluated by Oak Ridge National Laboratory for the Nuclear Regulatory Commission (NRC). During this report period, emphasis was placed on the evaluation of information pertinent to the Hanford site in southeastern Washington. Results on the sorption/solubility behavior of technetium, neptunium, and uranium in the basalt/water geochemical system are summarized and compared to the results of DOE. Also, summaries of results are reported from two geochemical modeling studies: (1) an evaluation of the information developed by DOE on the native copper deposits of Michigan as a natural analog for the emplacement of copper canisters in a repository in basalt, and (2) calculation of the solubility and speciation of radionuclides for representative groundwaters from the Yucca Mountain site in Nevada
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