Integrity and Integration: An Exploration of the Personal, Professional, and Pedagogical in the Professoriate

This paper seeks to explore the connections between the concepts of integrity and integration within the professoriate in Christian higher education. Specifically, it examines commonalities and intersections in the definitions of terms, the gaps between rhetoric and reality, and the reasons for those gaps. Implications for a professor’s inner life, scholarship, and teaching are also discussed, and suggestions for closing the gaps are offered

Quick Tips for Cleaning Up After a Flood (2011)

Families returning to their flooded homes should be cautious before and during the cleanup process. In addition to other hazards, floodwater may contain sewage and biological contaminants that can linger in the home after the initial cleanup.New 7/11/Web

Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria

Abstract Background Bacteria and mitochondria contain translocases that function to transport proteins across or insert proteins into their inner and outer membranes. Extant mitochondria retain some bacterial-derived translocases but have lost others. While BamA and YidC were integrated into general mitochondrial protein transport pathways (as Sam50 and Oxa1), the inner membrane TAT translocase, which uniquely transports folded proteins across the membrane, was retained sporadically across the eukaryote tree. Results We have identified mitochondrial TAT machinery in diverse eukaryotic lineages and define three different types of eukaryote-encoded TatABC-derived machineries (TatAC, TatBC and TatC-only). Here, we investigate TatAC and TatC-only machineries, which have not been studied previously. We show that mitochondria-encoded TatAC of the jakobid Andalucia godoyi represent the minimal functional pathway capable of substituting for the Escherichia coli TatABC complex and can transport at least one substrate. However, selected TatC-only machineries, from multiple eukaryotic lineages, were not capable of supporting the translocation of this substrate across the bacterial membrane. Despite the multiple losses of the TatC gene from the mitochondrial genome, the gene was never transferred to the cell nucleus. Although the major constraint preventing nuclear transfer of mitochondrial TatC is likely its high hydrophobicity, we show that in chloroplasts, such transfer of TatC was made possible due to modifications of the first transmembrane domain. Conclusions At its origin, mitochondria inherited three inner membrane translocases Sec, TAT and Oxa1 (YidC) from its bacterial ancestor. Our work shows for the first time that mitochondrial TAT has likely retained its unique function of transporting folded proteins at least in those few eukaryotes with TatA and TatC subunits encoded in the mitochondrial genome. However, mitochondria, in contrast to chloroplasts, abandoned the machinery multiple times in evolution. The overall lower hydrophobicity of the Oxa1 protein was likely the main reason why this translocase was nearly universally retained in mitochondrial biogenesis pathways

Strategic Analysis for a Not-for-Profit Biomedical Organization

MOT MBA Project-Simon Fraser Universit

Menstrual cycle phase does not predict political conservatism

Recent authors have reported a relationship between women's fertility status, as indexed by menstrual cycle phase, and conservatism in moral, social and political values. We conducted a survey to test for the existence of a relationship between menstrual cycle day and conservatism. 2213 women reporting regular menstrual cycles provided data about their political views. Of these women, 2208 provided information about their cycle date, 1260 provided additional evidence of reliability in self-reported cycle date, and of these, 750 also indicated an absence of hormonal disruptors such as recent hormonal contraception use, breastfeeding or pregnancy. Cycle day was used to estimate day-specific fertility rate (probability of conception); political conservatism was measured via direct self-report and via responses to the "Moral Foundations” questionnaire. We also recorded relationship status, which has been reported to interact with menstrual cycle phase in determining political preferences. We found no evidence of a relationship between estimated cyclical fertility changes and conservatism, and no evidence of an interaction between relationship status and cyclical fertility in determining political attitudes. Our findings were robust to multiple inclusion/exclusion criteria and to different methods of estimating fertility and measuring conservatism. In summary, the relationship between cycle-linked reproductive parameters and conservatism may be weaker or less reliable than previously thought

Best Management Practices for Salmonella and Campylobacter Control in Poultry Processing Plants

Campylobacter and Salmonella are the top two pathogens associated with poultry-related foodborne illness, currently responsible for over 800,000 illnesses annually (13). The reduction of these pathogens on commercial poultry products at the processing plant level is crucial to reducing the incidence of foodborne illness, as significant reduction in these pathogens prior to reaching the processing plant may not be easy. Currently, poultry processing plants use multiple intervention methods at various sites to reduce the Campylobacter and Salmonella load as much as possible, with few plant management practices being standard throughout poultry processing. The determination of these best practices is necessary to maximize the reduction of these foodborne pathogens while minimizing the cost and waste within the processing plant. Six poultry processing plants were analyzed in the Southeastern United States in order to evaluate their current pathogen control practices, suggest changes, and evaluate to the effectiveness of the changes. Surveys were sent to the plant Quality Assurance managers to determine production levels, antimicrobial interventions, and current pathogen testing practices. Then an initial sampling set was taken at each plant, at sites that included carcass samples before any pre-evisceration intervention, after exiting the inside-outside bird washer (IOBW), after exiting the pre-chiller, after exiting the primary chiller, and after exiting any post-chill intervention, as well as a water sample from each scalder, pre-chiller, primary chiller, and post-chill dip tank or finishing chiller, and finally a pooled manure sample to analyze incoming microbial load. Enumerations were performed for Campylobacter and Salmonella as well as enrichments for Campylobacter and Salmonella. After the initial sample set, each plant was suggested several changes to be made and once the changes were implemented a second sampling set was conducted to determine the effectiveness of these changes. The analysis of the various practices showed that peracetic acid (PAA) was the most effective antimicrobial currently in use. The use of a post-chill antimicrobial immersion tank and/or use of Cetylpyridinium Chloride CPC spray cabinet also displayed a further reduction in microbial levels when the primary chiller was not sufficient. Slight microbial buildup occurred in the immersion tanks, however effective cleaning techniques and chiller maintenance may minimize these negative effects. Further research on the use of PAA, CPC, and post-chill immersion tanks may help further optimize plant pathogen control practices throughout the United States

Speaker and Gavel Call for Submissions: Forensics Administration and Practice in the Age of Covid-19

Speaker and Gavel invites authors to submit manuscripts for an upcoming special edition focused on scholarship, pedagogy, research, competition, and administration in competitive and non-competitive speech and debate practices within and post the global Covid-19 pandemic. We welcome submissions from forensic coaches, communication scholars, and students (undergraduate and graduate)