We dream of an age that is equal to our passions

We dream of an age that is equal to our passions is a series of soliloquies and ideas that look at the false narratives I tell myself in order to get out bed in the morning, at the depression that came after failed revolutions, at the unrealistic hopes of my politics, and of my desire to become a whole human being

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels

The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and membrane-to-cytosol translocation of the fluorescent PIP2/inositol 1,4,5-trisphosphate (IP3)-binding peptide green fluorescent protein-tagged pleckstrin homology domain of phospholipase C (GFP-PLC delta-PH). The muscarinic receptor agonist oxotremorine-M produced parallel time- and concentration-dependent M-current inhibition and GFP-PLC delta-PH translocation; bradykinin also produced parallel time- dependent inhibition and translocation. Phosphatidylinositol-4-phosphate-5-kinase (PI5-K) overexpression reduced both M-current inhibition and GFP-PLC delta-PH translocation by both oxotremorine-M and bradykinin. These effects were partly reversed by wortmannin, which inhibits phosphatidylinositol-4-kinase (PI4-K). PI5-K overexpression also reduced the inhibitory action of oxotremorine-M on PIP2-gated G-protein-gated inward rectifier (Kir3.1/3.2) channels; bradykinin did not inhibit these channels. Overexpression of neuronal calcium sensor-1 protein (NCS-1), which increases PI4-K activity, did not affect responses to oxotremorine-M but reduced both fluorescence translocation and M-current inhibition by bradykinin. Using an intracellular IP3 membrane fluorescence-displacement assay, initial mean concentrations of membrane [PIP2] were estimated at 261 mu M (95% confidence limit; 192-381 mu M), rising to 693 mu M (417-1153 mu M) in neurons overexpressing PI5-K. Changes in membrane [PIP2] during application of oxotremorine-M were calculated from fluorescence data. The results, taken in conjunction with previous data for KCNQ2/3 (Kv7.2/Kv7.3) channel gating by PIP2 (Zhang et al., 2003), accorded with the hypothesis that the inhibitory action of oxotremorine-M on M current resulted from depletion of PIP2. The effects of bradykinin require additional components of action, which might involve IP3-induced Ca2+ release and consequent M-channel inhibition (as proposed previously) and stimulation of PIP2 synthesis by Ca2+-dependent activation of NCS-1

Toward a relational understanding of outdoor environmental education: A case study of two residential learning settings in South Devon, UK.

This thesis examines the ways in which outdoor environmental education can be understood in the context of relational-environmental encounters. The study focuses on residential learning programmes with secondary school students in the UK. The research aims to explore the extent to which current educational practices, structures and pedagogies in two case study locations can be said to occur as continuous lived experiences; invoking relational ontologies. Furthermore, this research examines the environmental encounters of students and considers how these encounters shape and challenge environmental narratives consisting social and cultural norms. Making use of developments within behaviour change theory, ecological ethics and environmental pedagogy, this thesis brings together ways of understanding environmental and sustainability education, notions of relational ways of being, and models for transformative societal change. The research methodology makes use of ethnographic encounters in two case locations comprising residential education centers in South Devon, UK, chosen for their representation of instrumental and emancipatory pedagogies. Participating in fifteen outdoor environmental education programmes over ten months, participant observation, focus groups, interviews and photo elicitation were deployed. In-field and subsequent thematic analysis, using structured coding elicited four central themes: structure, choice, relationships and discomfort. These themes formed the core empirical analysis and enabled an exploration of relational practices occurring across the spectrum of contemporary environmental education. The research therefore provides a narrative of residential experiences in a subjective, emergent and reciprocal environment, whereby both lived and learning experiences provide space for instrumental and emancipatory learning. Consequently, contributions are made to geography and education in four key areas; firstly, the articulation of a pedagogy of discomfort deployed explicitly and implicitly within environmental education; secondly, an advancement of relational connotations of place-making within environmental education as being emergent of agency, structure and the setting itself; thirdly, through the ecotheraputic ‘performance’ of other-than-human material and ecological environments in education discourses; and finally, through an advancement of a blended approach to environmental education, understood from an ecological-ethical, as well as a behavioural-practice perspective.Field Studies CouncilWhitley Wildlife Conservation Trus

Studies of arsenic spray residues on apples

During the 1954-55 and 1955-56 seasons two trials were carried out in the Stanthorpe district to obtain data on arsenic spray residues on apples. It is evident from these trials that lead arsenate is not weathered appreciably from the fruit, and durinq the season the gradual reduction in arsenic residue as p.p.m. As2O3 is largely the result of fruit growth. One 3 Ib./100 gal. spray applied to the variety Granny Smith at a dosage rate of 1 1/4 gal. per tree in late November resulted in residues of less than 0.6 p.p.m. at early harvest in early January, and at the same dosage rate and timings the mean residue from a double strength spray was 1.46 p.p.m

Phytophthora root rot of Pinus in Queensland

The incidence of Phytophthora root rot of Pinus spp. in Queensland is reported. Phytophthora cinnamomi was found to be the pathogen associated with. the disease in the nursery and the field. The pathogenicity of P. cinnamomi to a number of species of Pinus was investigated in greenhouse inoculation tests. P. boehmeriae was recorded from Pinus patula in one locality and pathogenicity was proven

Pinus damping-off investigations in southern Queensland

The organisms associated with damping off in Pinus nurseries in southern Queensland were investigated. The potential pathogenicity of a number of Pythium, Phytophthora, Rhizoctonia and Fusarium species to Pinus seedlings was checked in greenhouse inoculation tests. A damping-off control experiment showed that soil drenches of captan, thiram and copper· oxychloride will control the disease in seedlings of slash pine (Pinus elliottii var. elliottii)

Nitrite poisoning of pigs

Heavy mortality in pigs fed on soup prepared by cooking beef and offal in well water was investigated on two farms. It is considered that the mortality which occurred in pigs on these farms was due to nitrite poisoning and that the nitrite was derived from the nitrite in the well water