36 research outputs found
Detection of homozygosity in near isogenic Lines of non-susceptible to Zhenjiang strain of densonucleosis virus in silkworm
The near isogenic lines (NILs) of non-susceptible to DNV-Z were bred through backcrossing successively using L10 as donor parent and Js as recurrent parent. The homozygosity of the NILs was detected using the SSR markers from the SSR linkage map. The results showed that the ratio of the linkage groups from the recurrent parent in the NILs increased rapidly along with the increase of the backcrossing generations. After 6 generations of backcrossing, it was selfed and was fed with DNV-Z. The linkage groups of 9 of the 5 BC6 pairs, whose 1/4 offspring were non-susceptible to DNV-Z, were all replaced by the recurrent parent except the linkage group that held nsd-Z, and only part of one linkage group from the other one individual had not been replaced. According to the markers linked to nsd-Z, Fl0316 had not been replaced in all of the 10 individuals, but crossover happened in 2 individuals between Fl0568 and nsd-Z
Nanogap structures for molecular nanoelectronics
This study is focused on the realization of nanodevices for nano and molecular electronics, based on molecular interactions in a metal-molecule-metal (M-M-M) structure. In an M-M-M system, the electronic function is a property of the structure and can be characterized through I/V measurements. The contact between the metals and the molecule was obtained by gold nanogaps (with a dimension of less than 10 nm), produced with the electromigration technique. The nanogap fabrication was controlled by a custom hardware and the related software system. The studies were carried out through experiments and simulations of organic molecules, in particular oligothiophenes
Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice
Experimental and Theoretical Research on Shear Strength of Seismic-Damaged SRC Frame Columns Strengthened with Enveloped Steel Jackets
The experimental and shear strength analytical investigations carried out on seismic-damaged steel reinforced concrete (SRC) columns strengthened with enveloped steel jacket subjected to cyclic loading are presented in this paper. Four 1/2-scale SRC columns were designed and manufactured and the postearthquake damage, enveloped steel jacket-confined, and destructive tests were carried out under lateral cyclic loading. The effects of postearthquake damage degree and enveloped steel jacket-confined on shear capacity and ductility capacity were all well examined. Test results indicate that the ductility of seismic-damaged SRC columns strengthened with enveloped steel jacket increases with the reduction of the postearthquake damage degree. The results indicate that the calculation formula of shear bearing capacity of SRC columns is feasible. Based on GB50010-2010, ACI318-08, and CSA-04, three different shear models were established, and the calculated values of shear capacity are quite different, and the analysis of the shear strength of RC in the strengthened seismic-damaged SRC column cannot be ignored. The formula is verified, and the calculated results are consistent well with the experimental results
Shape-Dependent Aggregation of Silver Particles by Molecular Dynamics Simulation
In crystallization, nanoparticle aggregation often leads to the formation of orderly structures, even single crystals. Why can nanoparticles form orderly structures and what is the mechanism dominating their orderly aggregation? These questions raise interesting research problems, but the occurrences that could answer them often fail to be directly observed, since the interaction among particles is invisible. Here, we report an attempt to discover the interaction and aggregation of building blocks through a computer simulation, focusing on the shape effect of building blocks on the aggregation. Four types of silver building blocks were selected, each consisting of (100) and (111) facets, but the ratio of these two facets was different. It was found that the area of facets played an important role in selecting the aggregation mode. The facets with a large area and high energy had a high possibility of aggregation. In addition, the effects of solvent viscosity and temperature were also investigated. High viscosity and low temperature enhanced the orderliness of aggregation. This paper reports a detailed view of the aggregation process of silver nanoparticles, which is expected to be helpful in understanding the structure evolution of materials in nonclassical crystallization
