10,523 research outputs found
Engineering the Phase Front of Light with Phase-Change Material Based Planar lenses
International audienc
Podoplanin-positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion
Podoplanin (PDPN) is a well established lymphatic endothelial marker and has frequently been observed in cancer cells at the edge of cancer masses. Previous studies investigating the association between PDPN expression and patient prognosis have had contradictory results. In the present study, it was hypothesized that the different locations of PDPNpositive cells may explain these varying results. The present study aimed to focus on PDPN expression at the edge of esophageal cancer cell nests. In order to analyze the clinical significance of this PDPN expression, immunohistochemistry was performed using esophageal cancer tissue microarrays. PDPN expression at the edge of the cancer cell nest was found to be significantly associated with invasion (P<0.05) and poor prognosis (P<0.001) in patients with cancer. To further investigate the role of PDPN expression in cancer cells, the PDPN gene was cloned and transfected into esophageal squamous cell carcinoma (ESCC) cell lines. PDPN expression was also knocked down using small interfering RNA. PDPNpositive cancer cells were found to exhibit invasion characteristics. Thus, PDPN expression at the edge of a cancer cell nest may indicate invasion and represent a poor prognostic factor for ESCCs.published_or_final_versio
Two classes of nonlocal Evolution Equations related by a shared Traveling Wave Problem
We consider reaction-diffusion equations and Korteweg-de Vries-Burgers (KdVB)
equations, i.e. scalar conservation laws with diffusive-dispersive
regularization. We review the existence of traveling wave solutions for these
two classes of evolution equations. For classical equations the traveling wave
problem (TWP) for a local KdVB equation can be identified with the TWP for a
reaction-diffusion equation. In this article we study this relationship for
these two classes of evolution equations with nonlocal diffusion/dispersion.
This connection is especially useful, if the TW equation is not studied
directly, but the existence of a TWS is proven using one of the evolution
equations instead. Finally, we present three models from fluid dynamics and
discuss the TWP via its link to associated reaction-diffusion equations
Measurement of the Cross Section between 600 and 900 MeV Using Initial State Radiation
We extract the cross section in the energy
range between 600 and 900 MeV, exploiting the method of initial state
radiation. A data set with an integrated luminosity of 2.93 fb taken at
a center-of-mass energy of 3.773 GeV with the BESIII detector at the BEPCII
collider is used. The cross section is measured with a systematic uncertainty
of 0.9%. We extract the pion form factor as well as the
contribution of the measured cross section to the leading order hadronic vacuum
polarization contribution to . We find this value to be
.Comment: 14 pages, 7 figures, accepted by PL
Measurement of the Matrix Elements for the Decays and
Based on a sample of events collected with the
BESIII detector at the BEPCII collider, Dalitz plot analyses of selected 79,625
events, 33,908
events and 1,888
events are performed. The measured
matrix elements of are in reasonable agreement
with previous measurements. The Dalitz plot slope parameters of
and
are determined to be and , respectively, where the first uncertainties are statistical and the
second systematic. Both values are consistent with previous measurements, while
the precision of the latter one is improved by a factor of three. Final state
interactions are found to have an important role in those decays.Comment: 12 pages, 7 figure
Measurement of and search for
We report a measurement of the branching fraction of
and search for the transition
based on 2.92~fb of
data accumulated at ~GeV with the BESIII detector at the BEPCII
collider. The measured branching fraction of is , which is the most precise measurement to date.
The upper limit on the branching fraction of at a confidence level is . The corresponding partial widths are
~keV and
~keV
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