A recognition method of plunger wear degree of plunger pump using probability neural network

In order to increase the diagnosis efficiency of plunger wear fault, a recognition method is developed using sensitivity analysis and probability neural network. Firstly, 17 time domain characteristics of vibration signal are extracted. Then analyzed the sensitivity of characteristics to failure to select sensitive characteristics parameters. Finally, PNN method to identify the degree of plunger wear was proposed. A hydraulic pump fault simulation experiment was designed, and validated the proposed method by experimental data. The results show that the method can quickly and effectively identify the degree of plunger wear

Spare support model based on gamma degradation process

Spare parts ordering is very important in the domain of system support based on condition-based maintenance. For a single-unit system with condition monitoring, a joint degradation and spare parts ordering model is established in this paper to achieve the lowest total cost rate as the objective. The degradation process of system is assumed to be followed a gamma process. A decision on optimal spare ordering time by the improved cost rate model based on the proposed degradation model is made. Finally, a case analysis is implemented to demonstrate the effectiveness of the proposed model in this paper. Analysis results show that the proposed model can reduce the cost rate effectively

Theories and applications of tea residue adsorbing aroma compounds: a review

Tea leaves have a good natural adsorption capacity due to their numerous pore structures and high specific surface area. Along with the advancement of tea process technology, more and more sites of adsorption and binding have been found in tea leaves, thus further improving the adsorption performance. Based on the original biological structure and internal components of tea leaves, the adsorption mechanism in tea leaves for exogenous compounds is mainly divided into physical adsorption theory and chemical adsorption theory. Compared with original tea leaves, modified tea leaves significantly improve adsorption performance with a specific adsorption function, which could improve the utilization rate of tea leaves and their waste residues. Techniques such as scanning electron microscopy provide basic data support for exploring the adsorption mechanism of tea leaves at the level of material structure and a theoretical basis for the development of specific adsorbents. Additionally, the application of thermodynamic adsorption models and adsorption kinetic equations could help to understand the process of tea adsorbing exogenous compounds and to visualize the adsorption process. The adsorption of exogenous additives by tea residue could make use of the affinity between functional groups. In future, these mechanisms will lay the foundation for its application in the field of substance adsorption and improve the utilization efficiency of renewable resources similar to tea leaves

Interactions between curcumin and human salt-induced kinase 3 elucidated from computational tools and experimental methods

Natural products are widely used for treating mitochondrial dysfunction-related diseases and cancers. Curcumin, a well-known natural product, can be potentially used to treat cancer. Human salt-induced kinase 3 (SIK3) is one of the target proteins for curcumin. However, the interactions between curcumin and human SIK3 have not yet been investigated in detail. In this study, we studied the binding models for the interactions between curcumin and human SIK3 using computational tools such as homology modeling, molecular docking, molecular dynamics simulations, and binding free energy calculations. The open activity loop conformation of SIK3 with the ketoenol form of curcumin was the optimal binding model. The I72, V80, A93, Y144, A145, and L195 residues played a key role for curcumin binding with human SIK3. The interactions between curcumin and human SIK3 were also investigated using the kinase assay. Moreover, curcumin exhibited an IC50 (half-maximal inhibitory concentration) value of 131 nM, and it showed significant antiproliferative activities of 9.62 ± 0.33 µM and 72.37 ± 0.37 µM against the MCF-7 and MDA-MB-23 cell lines, respectively. This study provides detailed information on the binding of curcumin with human SIK3 and may facilitate the design of novel salt-inducible kinases inhibitors

Investigation on Numerical Simulation of Radiation Heating Thermal Environment in Car Cabin

Abstract Based on the automobile energy saving and requirements for thermal comfort of heating environment in a car, a capillary radiation heating system for automobile is presented, and the 3D flow field and temperature field of air in the passenger compartment are simulated by using SC/Tetra software. To consider the effect of human thermoregulation, human thermal regulatory model is incorporated with numerical simulation. The thermal comfort of passenger compartment is evaluated by PMV-PPD comfort index basing on the simulation results. It concludes that the distributions of flow field and temperature field of radiation heating environment are relatively homogeneous. Human thermoregulation has a big influence on the temperature distribution in the near region around the human body. Analyzing the PMV values of body surfaces, it concludes that the radiation penal surface temperature should be set to 30°C under the most comfortable environment for human. The research results provide basis for the using of radiation heating technology in a car.</jats:p

Multimodal Discourse Analysis Theory Applied to Senior High School English Reading Teaching

Reading English is required for high school students to gain language proficiency, enhance their cultural awareness, and broaden their global perspective. This study incorporates the theory of multimodal discourse analysis into English reading teaching for high school students based on the principles of social semiotics and systemic functional linguistics. The results indicate that utilizing multimodal discourse analysis theory in high school English reading enhances students' focus in class and boosts their English reading scores. Additionally, it facilitates their comprehension of text information and establishes a solid basis for developing multiple literacies. &nbsp; Keywords: Multimodal discourse analysis theory; Senior high school; English reading teachin

Design of Family Rooms for Environment-Friendly Hotels Based on Parent-Child Interaction

Abstract There has been a growing demand for family rooms of a hotel based on parent-child interactions as a result of the development of tourism. Unlike conventional designs of hotel rooms, the family room of hotels features a higher level of parent-child interactions. This paper investigated and studied literatures on the mentality and behaviors of children, and analyzed the mental needs of parents, aiming to boost parent-child interactions in an environment-friendly way. The paper proposed a design incorporating graffiti, window opening and holes in walls. By encouraging graffiti and design by parents and children, the room allows children to make a full use of imagination, practice manual skills and cultivate the awareness of environmental protection. The design fits the behavioral pattern of children and incorporate the elements of games, meeting the needs of both parents and children and enhancing the parent-child interactions of hotel family rooms.</jats:p