Road junction configurations and the severity of traffic accidents in Japan

In many countries, 40–60% of the traffic accidents occur at junctions, making the reduction of junction accidents paramount to achieving UN Sustainable Development Goals. In Japan, the road safety guidelines specify the proximity between junctions and non-perpendicular angles at junctions as the two main risk factors behind junction accidents, yet their impact remains understudied. Using binomial logistic regression models, this study investigates the impact of junction intervals and junction angles on the severity of traffic accidents. The study found that, in general, (1) shorter intervals between adjacent junctions helps reduce the risk of serious accidents, which is the opposite of the current road safety guidelines in Japan, and (2) results from the junction angle analysis were mixed but there was no evidence that the roads should meet at a right angle to reduce traffic accidents. Some types of accidents also returned a non-linear curve, e.g., vehicle-to-vehicle collisions at four-armed junctions involving a driver aged 65 years and over have the highest risk of fatal/serious accidents when adjacent junctions were 32 m apart, and the risk reduces at a shorter or longer interval. These results suggest that the current road safety guidelines require updating to improve road safety around junctions

CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) in 2018

While primary percutaneous coronary intervention (PCI) has significantly contributed to improve the mortality in patients with ST segment elevation myocardial infarction even in cardiogenic shock, primary PCI is a standard of care in most of Japanese institutions. Whereas there are high numbers of available facilities providing primary PCI in Japan, there are no clear guidelines focusing on procedural aspect of the standardized care. Whilst updated guidelines for the management of acute myocardial infarction were recently published by European Society of Cardiology, the following major changes are indicated; (1) radial access and drug-eluting stent over bare metal stent were recommended as Class I indication, and (2) complete revascularization before hospital discharge (either immediate or staged) is now considered as Class IIa recommendation. Although the primary PCI is consistently recommended in recent and previous guidelines, the device lag from Europe, the frequent usage of coronary imaging modalities in Japan, and the difference in available medical therapy or mechanical support may prevent direct application of European guidelines to Japanese population. The Task Force on Primary Percutaneous Coronary Intervention of the Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT) has now proposed the expert consensus document for the management of acute myocardial infarction focusing on procedural aspect of primary PCI

A Wolf-Rayet-like progenitor of SN 2013cu from spectral observations of a stellar wind.

The explosive fate of massive Wolf-Rayet stars (WRSs) is a key open question in stellar physics. An appealing option is that hydrogen-deficient WRSs are the progenitors of some hydrogen-poor supernova explosions of types IIb, Ib and Ic (ref. 2). A blue object, having luminosity and colours consistent with those of some WRSs, has recently been identified in pre-explosion images at the location of a supernova of type Ib (ref. 3), but has not yet been conclusively determined to have been the progenitor. Similar work has so far only resulted in non-detections. Comparison of early photometric observations of type Ic supernovae with theoretical models suggests that the progenitor stars had radii of less than 10(12) centimetres, as expected for some WRSs. The signature of WRSs, their emission line spectra, cannot be probed by such studies. Here we report the detection of strong emission lines in a spectrum of type IIb supernova 2013cu (iPTF13ast) obtained approximately 15.5 hours after explosion (by 'flash spectroscopy', which captures the effects of the supernova explosion shock breakout flash on material surrounding the progenitor star). We identify Wolf-Rayet-like wind signatures, suggesting a progenitor of the WN(h) subclass (those WRSs with winds dominated by helium and nitrogen, with traces of hydrogen). The extent of this dense wind may indicate increased mass loss from the progenitor shortly before its explosion, consistent with recent theoretical predictions

The Evolution of Compact Binary Star Systems

We review the formation and evolution of compact binary stars consisting of white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). Binary NSs and BHs are thought to be the primary astrophysical sources of gravitational waves (GWs) within the frequency band of ground-based detectors, while compact binaries of WDs are important sources of GWs at lower frequencies to be covered by space interferometers (LISA). Major uncertainties in the current understanding of properties of NSs and BHs most relevant to the GW studies are discussed, including the treatment of the natal kicks which compact stellar remnants acquire during the core collapse of massive stars and the common envelope phase of binary evolution. We discuss the coalescence rates of binary NSs and BHs and prospects for their detections, the formation and evolution of binary WDs and their observational manifestations. Special attention is given to AM CVn-stars -- compact binaries in which the Roche lobe is filled by another WD or a low-mass partially degenerate helium-star, as these stars are thought to be the best LISA verification binary GW sources.Comment: 105 pages, 18 figure

The visualization and analysis of urban facility pois using network kernel density estimation constrained by multi-factors

The urban facility, one of the most important service providers is usually represented by sets of points in GIS applications using POI (Point of Interest) model associated with certain human social activities. The knowledge about distribution intensity and pattern of facility POIs is of great significance in spatial analysis, including urban planning, business location choosing and social recommendations. Kernel Density Estimation (KDE), an efficient spatial statistics tool for facilitating the processes above, plays an important role in spatial density evaluation, because KDE method considers the decay impact of services and allows the enrichment of the information from a very simple input scatter plot to a smooth output density surface. However, the traditional KDE is mainly based on the Euclidean distance, ignoring the fact that in urban street network the service function of POI is carried out over a network-constrained structure, rather than in a Euclidean continuous space. Aiming at this question, this study proposes a computational method of KDE on a network and adopts a new visualization method by using 3-D "wall" surface. Some real conditional factors are also taken into account in this study, such as traffic capacity, road direction and facility difference. In practical works the proposed method is implemented in real POI data in Shenzhen city, China to depict the distribution characteristic of services under impacts of multi-factors

PTF13efv - An Outburst 500 Days Prior to the SNHUNT 275 Explosion and Its Radiative Efficiency

The American Astronomical Society. All rights reserved..The progenitors of some supernovae (SNe) exhibit outbursts with super-Eddington luminosities prior to their final explosions. This behavior is common among SNe IIn, but the driving mechanisms of these precursors are not yet well-understood. SNHunt 275 was announced as a possible new SN during 2015 May. Here we report on pre-explosion observations of the location of this event by the Palomar Transient Factory (PTF) and report the detection of a precursor about 500 days prior to the 2015 May activity (PTF 13efv). The observed velocities in the 2015 transient and its 2013 precursor absorption spectra are low (1000-2000 km s-1), so it is not clear yet if the recent activity indeed marks the final disruption of the progenitor. Regardless of the nature of this event, we use the PTF photometric and spectral observations, as well as Swift-UVOT observations, to constrain the efficiency of the radiated energy relative to the total kinetic energy of the precursor. We find that, using an order-of-magnitude estimate and under the assumption of spherical symmetry, the ratio of the radiated energy to the kinetic energy is in the range of 4 x 10-2 to 3.4 x 103. © 2016

Application of an indirect immunofluorescence test for detection of Mycoplasma pneumoniae in respiratory exudates

We prepared polyclonal antibody specific to Mycoplasma pneumoniae and examined the conditions influencing the ability of an indirect immunofluorescence test to detect the specific antigen in respiratory exudates. The antibody did not cross-react with normal human serum or with respiratory exudates from 10 healthy persons. Cross-reactivity of the antibody with species of mycoplasmas other than M. genitalium was fully diminished when absorbed with horse serum and yeast extract, components of the culture medium. Though the absorbed antibody cross-reacted with M. genitalium, the titer was significantly lower than when tested against M. pneumoniae. Two types of antigen-specific fluorescence were observed in clinical specimens: one is large or small fluorescent granular aggregates found in mucus, and the other is fine fluorescent particles diffused on the entire surface of small epithelial cells. Throat smears from 49 patients with serologically confirmed M. pneumoniae infections were examined by our indirect immunofluorescence method. Positive results were obtained in 42 cases, many of which were positive before a rise in serum antibody titer could be demonstrated, indicating that the method is useful for a preliminary diagnosis at an early stage of the infection.</jats:p

Is the internet really new after all?: the determinants of telecommunications diffusion in historical perspective

Recent anxieties over the digital divide have centered on the observation that uptake of the Internet is shaped by a number of identifiable, place-based factors. Yet is the Internet any more a product of material geography than previous communication technologies? Our contribution in this article seeks to address this question by deploying quantitative techniques to examine whether the country-level adoption of past communication networks—mail, telegrams, and telephone—was shaped by similar socioeconomic factors. Our results reveal striking similarities in the domestic attributes—income, education, and trade openness—influencing rates of uptake across all four technologies during their major periods of diffusion. © 2011 by Association of American Geographers