Molecularly Imprinted Polymers: Present and Future Prospective

Molecular Imprinting Technology (MIT) is a technique to design artificial receptors with a predetermined selectivity and specificity for a given analyte, which can be used as ideal materials in various application fields. Molecularly Imprinted Polymers (MIPs), the polymeric matrices obtained using the imprinting technology, are robust molecular recognition elements able to mimic natural recognition entities, such as antibodies and biological receptors, useful to separate and analyze complicated samples such as biological fluids and environmental samples. The scope of this review is to provide a general overview on MIPs field discussing first general aspects in MIP preparation and then dealing with various application aspects. This review aims to outline the molecularly imprinted process and present a summary of principal application fields of molecularly imprinted polymers, focusing on chemical sensing, separation science, drug delivery and catalysis. Some significant aspects about preparation and application of the molecular imprinting polymers with examples taken from the recent literature will be discussed. Theoretical and experimental parameters for MIPs design in terms of the interaction between template and polymer functionalities will be considered and synthesis methods for the improvement of MIP recognition properties will also be presented

MLB-PoL: A High Performance Hybrid Converter for Direct 48 V to Point-of-Load Applications

There is an increasing need for more efficient power conversion from 48 Vdc to point-of-load (PoL) applications in datacenters. This work presents a new hybrid converter with Multi-Level Binary (MLB) voltages on the flying capacitors that is well-suited for PoL applications with very high conversion ratios. The proposed MLB-PoL converter can be viewed as an 8-to-1 multi-phase doubler switched-capacitor (SC) converter merged with a two-phase interleaved buck converter. Compared to other two-phase hybrid SC topologies, multi-phase operation can help achieve higher conversion ratio in the SC stage with an equal or fewer number of components, and thus reduce the switch andinductor stress of the following buck stage. In addition, the output inductors in the proposed topology benefit from a frequency multiplication effect similar to that of the flying capacitor multilevel (FCML) converter. This can help further reduce the inductor size without increasing the switching frequency. A 48 V to 2.5-1.0 V converter prototype with 65 A output current was built and tested. At 48 V to 2 V, the prototype achieved 95.1% peak efficiency (94.3% including gate drive loss) and 395 W/in3 power density

An Integrator Time-Constant Calibration Scheme with Modified Voltage to Digital Converter

補正完畢國際札幌, 日本JP