4,602 research outputs found
Languaging in Content and Language Integrated Learning (CLIL) Classrooms: implications for English across the curriculum
Invited colloquiumLanguage is a primary semiotic (meaning-making) resource in construing the world, and the world (or content) is grasped mainly through language (Halliday, 1993). Hence, it has been argued that successful learning or knowledge construction depends on “guidance through interaction in the context of shared experience” (Rose & Martin, 2012, p. 58), or through the process of languaging, where language is used to mediate formulation of concepts (Swain & Lapkin, 2013). These highlight the importance of ‘dialogue’ or ‘dialogic discourse’. However, what actually constitutes ‘dialogic discourse’ and how this can be achieved by teachers and students in classrooms are still being explored, especially in Content and Language Integrated Learning (CLIL) classrooms, where such languaging processes and dialogic discourses take place through students’ (and often teachers’) ...postprin
Light-enhanced electro-optic spectral tuning in annealed proton-exchanged periodically poled lithium niobate channel waveguides
[[abstract]]We report the observation of light-enhanced electro-optic spectral tuning in annealed proton-exchanged, asymmetric domain-duty-cycle periodically poled lithium niobate (PPLN) channel waveguides for second-harmonic generation. The spectral tuning rate was increased rapidly from 0.07 nm/(kV/mm) to a saturated value of 0.32 nm/(kV/mm) in a 30%/70% domain-duty-cycle PPLN waveguide when the fundamental pump power near 1534 nm was increased from 0.6 to 46 mW. The second-harmonic laser power at 767 nm was identified to be the source enhancing he spectral tuning.[[fileno]]2030114010039[[department]]電機工程學
Electro-optic periodically poled lithium niobate Bragg modulator as a laser Q-switch
[[abstract]]We report an electro-optic Bragg modulator using a periodically poled lithium niobate (PPLN) crystal. We measured a half-wave voltage of 160 V when transmitting a 1064 nm laser through a 14.2 ram long, 780 mu m thick, 20.13 mu m period PPLN crystal at the Bragg angle. We also demonstrated a Q-switched Nd:YVO4 laser using such a PPLN Bragg modulator as its Q-switch, producing 7.8 us, 201 mu J pulses at a 10 kHz repetition rate when pumped by a 19.35 W diode laser at 808 run.[[fileno]]2030114010044[[department]]電機工程學
Extracellular Protease Inhibition Alters the Phenotype of Chondrogenically Differentiating Human Mesenchymal Stem Cells (MSCs) in 3D Collagen Microspheres
Matrix remodeling of cells is highly regulated by proteases and their inhibitors. Nevertheless, how would the chondrogenesis of mesenchymal stem cells (MSCs) be affected, when the balance of the matrix remodeling is disturbed by inhibiting matrix proteases, is incompletely known. Using a previously developed collagen microencapsulation platform, we investigated whether exposing chondrogenically differentiating MSCs to intracellular and extracellular protease inhibitors will affect the extracellular matrix remodeling and hence the outcomes of chondrogenesis. Results showed that inhibition of matrix proteases particularly the extracellular ones favors the phenotype of fibrocartilage rather than hyaline cartilage in chondrogenically differentiating hMSCs by upregulating type I collagen protein deposition and type II collagen gene expression without significantly altering the hypertrophic markers at gene level. This study suggests the potential of manipulating extracellular proteases to alter the outcomes of hMSC chondrogenesis, contributing to future development of differentiation protocols for fibrocartilage tissues for intervertebral disc and meniscus tissue engineering.published_or_final_versio
Evidence for non-self-similarity of microearthquakes recorded at a Taiwan borehole seismometer array
We investigate the relationship between seismic moment M0 and source duration tw of microearthquakes by using high-quality seismic data recorded with a vertical borehole array installed in central Taiwan. We apply a waveform cross-correlation method to the three-component records and identify several event clusters with high waveform similarity, with event magnitudes ranging from 0.3 to 2.0. Three clusters—Clusters A, B and C—contain 11, 8 and 6 events with similar waveforms, respectively. To determine how M0 scales with tw, we remove path effects by using a path-averaged Q. The results indicate a nearly constant tw for events within each cluster, regardless of M0, with mean values of tw being 0.058, 0.056 and 0.034 s for Clusters A, B and C, respectively. Constant tw, independent of M0, violates the commonly used scaling relation tw∝M1/30tw∝M01/3. This constant duration may arise either because all events in a cluster are hosted on the same isolated seismogenic patch, or because the events are driven by external factors of constant duration, such as fluid injections into the fault zone. It may also be related to the earthquake nucleation size
Molecular Characterization of an Atypical IncX3 Plasmid pKPC-NY79 Carrying blaKPC-2 in a Klebsiella pneumoniae
The IncX family of plasmids has recently been expanded to include at least four subtypes, IncX1-IncX4. The revised classification provides an opportunity for improving our understanding of the sequence diversity of the IncX plasmids and the resistance genes they carried. We described the complete nucleotide sequence of a novel IncX3 plasmid, pKPC-NY79 (42,447 bp) from a sequence-type 258 Klebsiella pneumoniae strain that was isolated from a patient who was hospitalized in New York, United States. In pKPC-NY79, the plasmid scaffold and genetic load region were highly similar to homologous regions in pIncX-SHV (IncX3, JN247852) and the bla KPC carrying pKpQIL (IncFII k, GU595196), respectively, indicating that it has possibly arisen through recombination of plasmids. The bla KPC-2 gene, as part of a transposon Tn4401a, was found within the genetic load region. The backbone of pKPC-NY79 differs from pIncX-SHV by a deletion involving the gene tandem hns-topB (encoding H-NS protein and topoisomerase III, respectively) and a putative ATPase gene. Unexpectedly, the impact of the hns-topB deletion on host fitness and plasmid stability was found to be small. In conclusion, the findings contribute to a better understanding of the plasmid platforms carrying bla KPC and of variations in the backbone of the IncX3 plasmids. © 2013 Springer Science+Business Media New York.postprin
Nodal dynamics, not degree distributions, determine the structural controllability of complex networks
Structural controllability has been proposed as an analytical framework for
making predictions regarding the control of complex networks across myriad
disciplines in the physical and life sciences (Liu et al.,
Nature:473(7346):167-173, 2011). Although the integration of control theory and
network analysis is important, we argue that the application of the structural
controllability framework to most if not all real-world networks leads to the
conclusion that a single control input, applied to the power dominating set
(PDS), is all that is needed for structural controllability. This result is
consistent with the well-known fact that controllability and its dual
observability are generic properties of systems. We argue that more important
than issues of structural controllability are the questions of whether a system
is almost uncontrollable, whether it is almost unobservable, and whether it
possesses almost pole-zero cancellations.Comment: 1 Figures, 6 page
Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China
postprin
Urban energy consumption and CO2 emissions in Beijing: current and future
This paper calculates the energy consumption and CO2 emissions of Beijing over 2005–2011 in light of the Beijing’s energy balance table and the carbon emission coefficients of IPCC. Furthermore, based on a series of energy conservation planning program issued in Beijing, the Long-range Energy Alternatives Planning System (LEAP)-BJ model is developed to study the energy consumption and CO2 emissions of Beijing’s six end-use sectors and the energy conversion sector over 2012–2030 under the BAU scenario and POL scenario. Some results are found in this research: (1) During 2005–2011, the energy consumption kept increasing, while the total CO2 emissions fluctuated obviously in 2008 and 2011. The energy structure and the industrial structure have been optimized to a certain extent. (2) If the policies are completely implemented, the POL scenario is projected to save 21.36 and 35.37 % of the total energy consumption and CO2 emissions than the BAU scenario during 2012 and 2030. (3) The POL scenario presents a more optimized energy structure compared with the BAU scenario, with the decrease of coal consumption and the increase of natural gas consumption. (4) The commerce and service sector and the energy conversion sector will become the largest contributor to energy consumption and CO2 emissions, respectively. The transport sector and the industrial sector are the two most potential sectors in energy savings and carbon reduction. In terms of subscenarios, the energy conservation in transport (TEC) is the most effective one. (5) The macroparameters, such as the GDP growth rate and the industrial structure, have great influence on the urban energy consumption and carbon emissions
Spinoza
"Spinoza", second edition.
Encyclopedia entry for the Springer Encyclopedia of EM Phil and the Sciences, ed. D. Jalobeanu and C. T. Wolfe
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