48,989 research outputs found
An Online Updating Approach for Testing the Proportional Hazards Assumption with Streams of Big Survival Data
The Cox model, which remains as the first choice in analyzing time-to-event
data even for large datasets, relies on the proportional hazards assumption.
When the data size exceeds the computer memory, the standard statistics for
testing the proportional hazards assumption can no longer b e easily
calculated. We propose an online up dating approach with minimal storage
requirement that up dates the standard test statistic as each new block of data
becomes available. Under the null hypothesis of proportional hazards, the
proposed statistic is shown to have the same asymptotic distribution as the
standard version if it could be computed with a super computer. In simulation
studies, the test and its variant based on most recent data blocks maintain
their sizes when the proportional hazards assumption holds and have substantial
power to detect different violations of the proportional hazards assumption.
The approach is illustrated with the survival analysis of patients with
lymphoma cancer from the Surveillance, Epidemiology, and End Results Program.
The proposed test promptly identified deviation from the proportional hazards
assumption that was not captured by the test based on the entire data
The radiative decays of and heavy mesons
The radiative decay is believed to be an ideal lab to study hadronic
structure of newly observed resonances because the reactions are governed by
only the electromagnetic interaction (tree level). However, to obtain correct
theoretical values, one has to properly deal with the non-perturbative QCD
effects in the wavefunction and hadronization. In this work we derive the
formulas for the radiative decays of and heavy mesons in the
light front quark model (LFQM). Because is well measured, the theoretical evaluation of the transition
rate can be used to test our approach. Within this theoretical framework, the
width of is evaluated. The formulas
can be applied to identify the inner structures of new resonances, for example
the isospin of and the structure of , via processes
, and
.Comment: 10 pages, 1 figure, Accepted by PR
Constraints on the Asymptotic Baryon Fractions of Galaxy Clusters at Large Radii
While X-ray measurements have so far revealed an increase in the
volume-averaged baryon fractions of galaxy clusters with cluster radii
, should asymptotically reach a universal value ,
provided that clusters are representative of the Universe. In the framework of
hydrostatic equilibrium for intracluster gas, we have derived the necessary
conditions for : The X-ray surface brightness profile
described by the model and the temperature profile approximated by the
polytropic model should satisfy and
for , respectively, which sets
a stringent limit to the polytropic index: . In particular, a
mildly increasing temperature with radius is required if the observationally
fitted parameter is in the range . It is likely that a
reliable determination of the universal baryon fraction can be achieved in the
small clusters because the disagreement between the exact and
asymptotic baryon fractions for clusters with breaks down at rather
large radii (\ga30r_c) where hydrostatic equilibrium has probably become
inapplicable. We further explore how to obtain the asymptotic value
of baryon fraction from the X-ray measurement made primarily over
the finite central region of a cluster. We demonstrate our method using a
sample of 19 strong lensing clusters, which enables us to place a useful
constraint on : .
An optimal estimate of based on three cooling flow clusters with
or .Comment: 6 pages + 4 figures; accepted for publication in MNRA
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