Deep Eyes: Binocular Depth-from-Focus on Focal Stack Pairs

Human visual system relies on both binocular stereo cues and monocular focusness cues to gain effective 3D perception. In computer vision, the two problems are traditionally solved in separate tracks. In this paper, we present a unified learning-based technique that simultaneously uses both types of cues for depth inference. Specifically, we use a pair of focal stacks as input to emulate human perception. We first construct a comprehensive focal stack training dataset synthesized by depth-guided light field rendering. We then construct three individual networks: a Focus-Net to extract depth from a single focal stack, a EDoF-Net to obtain the extended depth of field (EDoF) image from the focal stack, and a Stereo-Net to conduct stereo matching. We show how to integrate them into a unified BDfF-Net to obtain high-quality depth maps. Comprehensive experiments show that our approach outperforms the state-of-the-art in both accuracy and speed and effectively emulates human vision systems

Dual use of LED traffic signal system

The dual use, signaling and communication, of LED traffic signal system is described and analyzed. The primary function of a traffic light system is to give traffic and pedestrian signals. A prototype of LED traffic signal head is developed to perform a secondary function: communication. A wireless communication link is set up using the LED traffic signal head as the transmitter. The LEDs are modulated to transmit information-carrying light. The receiver uses a silicon photodiode to detect the transmitted radiation. Using visible light as the transmission medium, a 1 Mbit/s wireless data link is obtained.published_or_final_versio

KIAA1114, a full-length protein encoded by the trophinin gene, is a novel surface marker for isolating tumor-initiating cells of multiple hepatocellular carcinoma subtypes

Identification of novel biomarkers for tumor-initiating cells (TICs) is of critical importance for developing diagnostic and therapeutic strategies against cancers. Here we identified the role of KIAA1114, a full-length translational product of the trophinin gene, as a distinctive marker for TICs in human liver cancer by developing a DNA vaccine-induced monoclonal antibody targeting the putative extracellular domain of KIAA1114. Compared with other established markers of liver TICs, KIAA1114 was unique in that its expression was detected in both alpha fetoprotein (AFP)-positive and AFP-negative hepatocellular carcinoma (HCC) cell lines with the expression levels of KIAA1114 being positively correlated to their tumorigenic potentials. Notably, KIAA1114 expression was strongly detected in primary hepatic tumor, but neither in the adjacent non-tumorous tissue from the same patient nor normal liver tissue. KIAA1114(high) cells isolated from HCC cell lines displayed TIC-like features with superior functional and phenotypic traits compared to their KIAA1114(low) counterparts, including tumorigenic abilities in xenotransplantation model, in vitro colony- and spheroid-forming capabilities, expression of stemness-associated genes, and migratory capacity. Our findings not only address the value of a novel antigen, KIAA1114, as a potential diagnostic factor of human liver cancer, but also as an independent biomarker for identifying TIC populations that could be broadly applied to the heterogeneous HCC subtypes.X1110Nsciescopu

Dimerization-Induced Fermi-Surface Reconstruction in IrTe2

We report a de Haas-van Alphen (dHvA) oscillation study on IrTe2 single crystals showing complex dimer formations. By comparing the angle dependence of dHvA oscillations with band structure calculations, we show distinct Fermi surface reconstruction induced by a 1/5-type and a 1/8-type dimerizations. This verifies that an intriguing quasi-two-dimensional conducting plane across the layers is induced by dimerization in both cases. A phase transition to the 1/8 phase with higher dimer density reveals that local instabilities associated with intra-and interdimer couplings are the main driving force for complex dimer formations in IrTe2.X11149sciescopu

Poly[dimethylammonium aquadi-μ-oxalato-europate(III) trihydrate]

In the crystal structure of the polymeric title compound, (C2H8N)[Eu(C2O4)2(H2O)]·3H2O, the independent oxalate that lies on a general position chelates to two Eu atoms, as do the other two oxalates that lie on different centres of inversion, the bridging mode of the oxalates giving rise to a three-dimensional anionic network. The water-coordinated Eu atom exists in a tricapped trigonal–prismatic geometry. The cations and solvent water mol­ecules occupy the cavities of the network and are involved in hydrogen bonding with each other and with the network.published_or_final_versio

Nanofibers Fabricated Using Triaxial Electrospinning as Zero Order Drug Delivery Systems

A new strategy for creating functional trilayer nanofibers through triaxial electrospinning is demonstrated. Ethyl cellulose (EC) was used as the filament-forming matrix in the outer, middle, and inner working solutions and was combined with varied contents of the model active ingredient ketoprofen (KET) in the three fluids. Triaxial electrospinning was successfully carried out to generate medicated nanofibers. The resultant nanofibers had diameters of 0.74 ± 0.06 μm, linear morphologies, smooth surfaces, and clear trilayer nanostructures. The KET concentration in each layer gradually increased from the outer to the inner layer. In vitro dissolution tests demonstrated that the nanofibers could provide linear release of KET over 20 h. The protocol reported in this study thus provides a facile approach to creating functional nanofibers with sophisticated structural features

Deep Burst Denoising

Noise is an inherent issue of low-light image capture, one which is exacerbated on mobile devices due to their narrow apertures and small sensors. One strategy for mitigating noise in a low-light situation is to increase the shutter time of the camera, thus allowing each photosite to integrate more light and decrease noise variance. However, there are two downsides of long exposures: (a) bright regions can exceed the sensor range, and (b) camera and scene motion will result in blurred images. Another way of gathering more light is to capture multiple short (thus noisy) frames in a "burst" and intelligently integrate the content, thus avoiding the above downsides. In this paper, we use the burst-capture strategy and implement the intelligent integration via a recurrent fully convolutional deep neural net (CNN). We build our novel, multiframe architecture to be a simple addition to any single frame denoising model, and design to handle an arbitrary number of noisy input frames. We show that it achieves state of the art denoising results on our burst dataset, improving on the best published multi-frame techniques, such as VBM4D and FlexISP. Finally, we explore other applications of image enhancement by integrating content from multiple frames and demonstrate that our DNN architecture generalizes well to image super-resolution

Charge ordering, ferroelectric, and magnetic domains in LuFe2O4 observed by scanning probe microscopy

LuFe2O4 is a multiferroic system which exhibits charge order, ferroelectricity, and ferrimagnetism simultaneously below similar to 230 K. The ferroelectric/charge order domains of LuFe2O4 are imaged with both piezoresponse force microscopy (PFM) and electrostatic force microscopy (EFM), while the magnetic domains are characterized by magnetic force microscopy (MFM). Comparison of PFM and EFM results suggests that the proposed ferroelectricity in LuFe2O4 is not of usual displacive type but of electronic origin. Simultaneous characterization of ferroelectric/charge order and magnetic domains by EFM and MFM, respectively, on the same surface of LuFe2O4 reveals that both domains have irregular patterns of similar shape, but the length scales are quite different. The domain size is approximately 100 nm for the ferroelectric domains, while the magnetic domain size is much larger and gets as large as 1 mu m. We also demonstrate that the origin of the formation of irregular domains in LuFe2O4 is not extrinsic but intrinsic. (c) 2015 AIP Publishing LLC.open11116sciescopu

Electrospun pH-sensitive core-shell polymer nanocomposites fabricated using a tri-axial process

A modified tri-axial electrospinning process was developed for the generation of a new type of pH-sensitive polymer/lipid nanocomposite. The systems produced are able to promote both dissolution and permeation of a model poorly water-soluble drug. First, we show that it is possible to run a tri-axial procress with only one of the three fluids being electrospinnable. Using an electrospinnable middle fluid of Eudragit S100 (ES100) with pure ethanol as the outer solvent and an unspinnable lecithin-diclofenac sodium (PL-DS) core solution, nanofibers with linear morphology and clear core/shell structures can be fabricated continuously and smoothly. X-ray diffraction proved that these nanofibers are structural nanocomposites with the drug present in an amorphous state. In vitro dissolution tests demonstrated that the formulations could preclude release in acidic conditions, and that the drug was released from the fibers in two successive steps at neutral pH. The first step is the dissolution of the shell ES100 and the conversion of the core PL-DS into sub-micron sized particles. This frees some DS into solution, and later the remaining DS is gradually released from the PL-DS particles through diffusion. Ex vivo permeation results showed that the composite nanofibers give a more than two-fold uplift in the amount of DS passing through the colonic membrane as compared to pure DS; 74% of the transmitted drug was in the form of PL-DS particles. The new tri-axial electrospinning process developed in this work provides a platform to fabricate structural nanomaterials, and the core-shell polymer-PL nanocomposites we have produced have significant potential applications for oral colon-targeted drug delivery. STATEMENT OF SIGNIFICANCE: A modified tri-axial electrospinning is demonstrated to create a new type of core-shell pH-sensitive polymer/lipid nanocomposites, in which an electrospinnable middle fluid is exploited to support the un-spinnable outer and inner fluids. The structural nanocomposites are able to provide a colon-targeted sustained release and an enhanced permeation performance of diclofenac sodium. The developed tri-axial process can provide a platform for fabricating new structural nanomaterials with high quality. The strategy of a combined usage of polymeric excipients and phosphilipid in a core-shell format should provide new possibilities of developing novel drug delivery systems for efficacious oral administration of poorly-water soluble drugs

Port safety evaluation from a captain's perspective: The Korean experience

There are many factors affecting navigational safety in ports, including weather, the characteristics of the channels and vessel types, etc. This paper aims to identify the factors influencing navigational safety in ports and to analyze the extent to which such factors affect the safety of ports from the perspective of ship captains through a real case study. A quantitative analysis is carried out using the data collected from 21 captains who have over 10. years experience in operating ships individually. The identified factors indicate risk implications in ports. A fuzzy analytical hierarchy process is used to evaluate the importance of the factors and to rank the safety levels of the targeted ports in Korea from a captain's perspective. Consequently, among Busan, Ulsan, Gwangyang, Incheon, and Mokpo, Busan is evaluated by captains as the safest port, while Mokpo is the most risky. The research also reveals that it is applicable to use domain expert knowledge when historical failure data is unavailable or difficult to access to evaluate port safety. The result shows great research significance in terms of providing relevant stakeholders, such as port authorities and shipping companies, with an insight into port safety performance and thus facilitating the development of the associated risk control measures. © 2014 Elsevier Ltd