Second-order accurate genuine BGK schemes for the ultra-relativistic flow simulations

This paper presents second-order accurate genuine BGK (Bhatnagar-Gross-Krook) schemes in the framework of finite volume method for the ultra-relativistic flows. Different from the existing kinetic flux-vector splitting (KFVS) or BGK-type schemes for the ultra-relativistic Euler equations, the present genuine BGK schemes are derived from the analytical solution of the Anderson-Witting model, which is given for the first time and includes the "genuine" particle collisions in the gas transport process. The BGK schemes for the ultra-relativistic viscous flows are also developed and two examples of ultra-relativistic viscous flow are designed. Several 1D and 2D numerical experiments are conducted to demonstrate that the proposed BGK schemes not only are accurate and stable in simulating ultra-relativistic inviscid and viscous flows, but also have higher resolution at the contact discontinuity than the KFVS or BGK-type schemes.Comment: 41 pages, 13 figure

Enabling Multi-level Trust in Privacy Preserving Data Mining

Privacy Preserving Data Mining (PPDM) addresses the problem of developing accurate models about aggregated data without access to precise information in individual data record. A widely studied \emph{perturbation-based PPDM} approach introduces random perturbation to individual values to preserve privacy before data is published. Previous solutions of this approach are limited in their tacit assumption of single-level trust on data miners. In this work, we relax this assumption and expand the scope of perturbation-based PPDM to Multi-Level Trust (MLT-PPDM). In our setting, the more trusted a data miner is, the less perturbed copy of the data it can access. Under this setting, a malicious data miner may have access to differently perturbed copies of the same data through various means, and may combine these diverse copies to jointly infer additional information about the original data that the data owner does not intend to release. Preventing such \emph{diversity attacks} is the key challenge of providing MLT-PPDM services. We address this challenge by properly correlating perturbation across copies at different trust levels. We prove that our solution is robust against diversity attacks with respect to our privacy goal. That is, for data miners who have access to an arbitrary collection of the perturbed copies, our solution prevent them from jointly reconstructing the original data more accurately than the best effort using any individual copy in the collection. Our solution allows a data owner to generate perturbed copies of its data for arbitrary trust levels on-demand. This feature offers data owners maximum flexibility.Comment: 20 pages, 5 figures. Accepted for publication in IEEE Transactions on Knowledge and Data Engineerin

Characterization of Laser-Resistant Port Wine Stain Blood Vessels Using In Vivo Reflectance Confocal Microscopy.

Background and objectivesPort wine stain (PWS) is a congenital vascular malformation of the human skin. Laser is the treatment of choice for PWS. Laser-resistant PWS is one crucial factor accounting for inadequate treatment outcome, which needs to be fully characterized. This study aims to quantitatively characterize the morphology of laser-resistant PWS blood vessels in the upper papillary dermis using in vivo reflectance confocal microscopy (RCM).Study design/materials and methodsA total of 42 PWS subjects receiving laser treatment from August 2016 through July 2018 were enrolled into this study. Thirty-three subjects had facial PWS; nine had extremity PWS. All subject's PWS received multiplex 585/1,064 nm laser treatment. RCM images were taken before and after treatment. The density, diameter, blood flow, and depth of PWS blood vessels were analyzed.ResultsWe found 44.4% PWS on the extremities (four out of nine subjects) were laser-resistant, which was significantly higher (P < 0.001) when compared with those PWS on the face (15.2%, 5 out of 33 subjects). The laser-resistant facial PWS blood vessels had significantly higher blood flow (1.35 ± 0.26 U vs. 0.89 ± 0.22 U, P < 0.001), larger blood vessel diameters (109.60 ± 18.24 µm vs. 84.36 ± 24.04 µm, P = 0.033) and were located deeper in the skin (106.01 ± 13.87 µm vs. 87.82 ± 12.57 µm, P < 0.001) in the skin when compared with laser-responsive PWS on the face. The average PWS blood vessel density (17.01 ± 4.63/mm2 vs. 16.61 ± 4.44/mm2 , P = 0.857) was not correlated to the laser resistance.ConclusionsLaser-resistant PWS blood vessels had significantly higher blood flow, larger diameters, and were located deeper in the skin. RCM can be a valuable tool for a prognostic evaluation on laser-resistant lesions before treatment, thereby providing guidance for tailored laser treatment protocols, which may improve the therapeutic outcome. The limitations for this study include relative small sample size and acquisitions of different blood vessels before and after 2 months of treatment. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc

Effect of a booster dose of influenza vaccine in patients with hemodialysis, peritoneal dialysis and renal transplant recipients: A systematic literature review and meta-analysis

Booster influenza vaccination has been recommended for patients with chronic renal disease in order to enhance the immune response to the influenza vaccine; however, the efficacy of a booster influenza vaccination is a matter of controversy. Therefore, we made a meta-analysis to determine the efficacy in patients with hemodialysis (HD), peritoneal dialysis (PD) and renal transplant recipient (RT). The sero-protection rate was used as a serologic parameter to describe the immune response to the vaccine. Statistical analysis was performed to calculate the pooled rate difference (RD) and 95% confidence interval (CI). The pooled RD for the H1N1, H3N2 and B influenza vaccines was 0.02 (95% CI: −0.02–0.06), 0.05 (95% CI: −0.01–0.11), 0.04 (95% CI: −0.02–0.10), respectively. We concluded that a booster dose of the influenza vaccine did not effectively enhance immunogenicity. Therefore, a booster dose of vaccine is not recommended for patients with hemodialysis, peritoneal dialysis and renal transplant recipients.Natural Science Foundation of Guangdong Province, Chin

The Flash ADC system and PMT waveform reconstruction for the Daya Bay Experiment

To better understand the energy response of the Antineutrino Detector (AD), the Daya Bay Reactor Neutrino Experiment installed a full Flash ADC readout system on one AD that allowed for simultaneous data taking with the current readout system. This paper presents the design, data acquisition, and simulation of the Flash ADC system, and focuses on the PMT waveform reconstruction algorithms. For liquid scintillator calorimetry, the most critical requirement to waveform reconstruction is linearity. Several common reconstruction methods were tested but the linearity performance was not satisfactory. A new method based on the deconvolution technique was developed with 1% residual non-linearity, which fulfills the requirement. The performance was validated with both data and Monte Carlo (MC) simulations, and 1% consistency between them has been achieved