Educational-pedagogical games in the formation of professionalism of a future teacher.

У статті розглядається один із активних методів навчання у ВНЗ – навчально-педагогічні ігри. Висвітлюється практика їх застосування при читанні педагогічних дисциплін. Educational-pedagogical games in the formation of professionalism of a future teacher. One of the active teaching methods at the HEI that is educational-pedagogical games is cleared up in this article. It also finds out their practical-applying in teaching pedagogical subjects.Виконано на кафедрі педагогіки дошкільної та початкової освіт

Загальний огляд силових установок для безпілотних авіаційних систем

This article is devoted to general overview of nowadays existent power plants intended for use in unmanned aircraft systems and types of fuel or sources of energy that can be used in power plants using open source of information.С помощью открытых источников информации сделан общий обзор существующих на сегодняшний день силовых установок предназначенных для использования в беспилотных авиационных системах, типов топлива и источников энергии, которые могут использоваться в силовых установках.За допомогою відкритих джерел інформації зроблено загальний огляд наявних на сьогоднішній день силових установок призначених для використання у безпілотних авіаційних системах, типів палива й джерел енергії, які можуть використовуватись в силових установках

Antibiotics and antiseptics for pressure ulcers

Background: Pressure ulcers, also known as bedsores, decubitus ulcers and pressure injuries, are localised areas of injury to the skin or the underlying tissue, or both. A range of treatments with antimicrobial properties, including impregnated dressings, are widely used in the treatment of pressure ulcers. A clear and current overview is required to facilitate decision making regarding use of antiseptic or antibiotic therapies in the treatment of pressure ulcers. This review is one of a suite of Cochrane reviews investigating the use of antiseptics and antibiotics in different types of wounds. It also forms part of a suite of reviews investigating the use of different types of dressings and topical treatments in the treatment of pressure ulcers. Objectives: To assess the effects of systemic and topical antibiotics, and topical antiseptics on the healing of infected and uninfected pressure ulcers being treated in any clinical setting. Search methods: In October 2015 we searched: the Cochrane Wounds Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library), Ovid MEDLINE, Ovid MEDLINE (In-Process & Other Non-Indexed Citations), Ovid EMBASE, and EBSCOCINAHL Plus.We also searched three clinical trials registries and the references of included studies and relevant systematic reviews. There were no restrictions based on language or date of publication or study setting. Selection criteria: Randomised controlled trials which enrolled adults with pressure ulcers of stage II or above were included in the review. Data collection and analysis: Two review authors independently performed study selection, risk of bias assessment and data extraction. Main results: We included 12 trials (576 participants); 11 had two arms and one had three arms. All assessed topical agents, none looked at systemic antibiotics. The included trials assessed the following antimicrobial agents: povidone iodine, cadexomer iodine, gentian violet, lysozyme, silver dressings, honey, pine resin, polyhexanide, silver sulfadiazine, and nitrofurazone with ethoxy-diaminoacridine. Comparators included a range of other dressings and ointments without antimicrobial properties and alternative antimicrobials. Each comparison had only one trial, participant numbers were low and follow-up times short. The evidence varied from moderate to very low quality. Six trials reported the primary outcome of wound healing. All except one compared an antiseptic with a non-antimicrobial comparator. There was some moderate and low quality evidence that fewer ulcers may heal in the short term when treated with povidone iodine compared with non-antimicrobial alternatives (protease-modulating dressings (risk ratio (RR) 0.78, 95% confidence interval (CI) 0.62 to 0.98) and hydrogel (RR 0.64, 95%CI 0.43 to 0.97)); and no clear difference between povidone iodine and a third non-antimicrobial treatment (hydrocolloid) (low quality evidence). Pine resin salve may heal more pressure ulcers than hydrocolloid (RR 2.83, 95% CI 1.14 to 7.05) (low quality evidence). There is no clear difference between cadexomer iodine and standard care, and between honey a combined antiseptic and antibiotic treatment (very low quality evidence). Six trials reported adverse events (primary safety outcome). Four reported no adverse events; there was very low quality evidence from one showing no clear evidence of a difference between cadexomer iodine and standard care; in one trial it was not clear whether data were appropriately reported. There was limited reporting of secondary outcomes. The five trials that reported change in wound size as a continuous outcome did not report any clear evidence favouring any particular antiseptic/anti-microbial treatments. For bacterial resistance, one trial found some evidence of more MRSA eradication in participants with ulcer treated with a polyhexanide dressing compared with a polyhexanideswab (RR 1.48, 95% CI 1.02 to 2.13); patients in the dressing group also reported less pain (MD −2.03, 95% CI −2.66 to −1.40). There was no clear evidence of a difference between interventions in infection resolution in three other comparisons. Evidence for secondary outcomes varied from moderate to very low quality; where no GRADE assessment was possible we identified substantial limitations which an assessment would have taken into account. Authors’ conclusions: The relative effects of systemic and topical antimicrobial treatments on pressure ulcers are not clear. Where differences in wound healing were found, these sometimes favoured the comparator treatment without antimicrobial properties. The trials are small, clinically heterogenous, generally of short duration, and at high or unclear risk of bias. The quality of the evidence ranges from moderate to very low; evidence on all comparisons was subject to some limitations

Comparative toxicological and hygienic assessment and combined action of modern fungicides based on azoxystrobin, pydiflumetofen, propiconazole

Annotation. The creation of combined pesticide formulations for the purpose of more effective protection of agricultural crops is a significant factor in the importance of assessing their synergistic effects. Substances that produce a similar pesticidal effect, in combination with each other, can enhance the toxic effect and, therefore, show dose additivity. The aim is toxicological and hygienic evaluation and determination of the type of combined action of pydiflumetofen, azoxystrobin and propiconazole – the active substances of the mixed formulations “Miravis Ace 275 SE” and “Miravis Neo 300 SE” according to toxicity indicators. Analytical review of scientific publications was carried out using data from EFSA, FAO, ECHA, PPDB, Internet sites. According to the literature, a comparative toxicological-hygienic evaluation of fungicidal preparations and their active substances was carried out. The general mechanism of fungicidal action was evaluated according to the classification developed by the Fungicide Resistance Action Committee (FRAC). The hazard class according to the toxic metric parameters of the substances under study was determined in accordance with the Hygienic classification of pesticides according to the degree of hazard (DSanPiN 8.8.1.002-98). The nature and type of combined action was carried out according to the Finney method with evaluation according to the criteria of acute toxicity. Systematization of data, their structuring for the purpose of further toxicological assessment of substances at the level of their inactive and threshold doses was carried out in the table editor Microsoft Excel 2019 (Microsoft Office 2019, Microsoft). As a result of the conducted research, the most toxic mixed fungicide “Miravis Neo 300 SE” based on three active substances was determined (the average lethal dose (LD50) is 550 mg/kg). It has been established that in cases of combinations of active substances to obtain a lethal effect, a dose of substances that does not exceed 100% in total is required, which indicates the strengthening (potentiation) of toxicity. It was pointed out that the share of propiconazole in the potentiation of the toxic effect in both mixed preparations is the highest compared to other active substances and is 0.87 for “Miravis Neo 300 SE” and 0.88 for “Miravis Ace 275 SE”. It was observed that the adverse effects of simultaneous exposure to several pesticides may change during the transition from acute to chronic exposure. Therefore, it is important to continue the research of the active substances of pesticides with the determination of limiting criteria for harmfulness, taking into account the remote effects of exposure. Thus, the toxicological and hygienic assessment made it possible to establish that the combined fungicides “Miravis Neo 300 SE” and “Miravis Ace 275 SE” are more toxic in the mode of single oral exposure in comparison with the single-component fungicide “Miravis 200 SC”. Increased toxicity (potentiation) can be considered as a consequence of the simultaneous exposure of several active substances. The active substance propiconazole poses the main danger of adverse effects on the body at the level of lethal doses. The obtained values of the potentiation coefficients will be taken into account in further studies of the risk assessment of complex and combined effects of pesticides on workers and their potential danger when entering the human body with food products.</jats:p

SYNCHRONIZATION OF COMPETENCIES OF PRESCHOOL AND PRIMARY EDUCATION AS A REQUIREMENT OF NOWADAYS

The relevance of the study is due to the priority of the principles of continuity and prospects of modern education, compliance with which will ensure the holistic formation of personality during all years of study in educational institutions. Maintaining continuity with the preschool period of childhood, primary school ensures the further development of the child's personality, its physical, intellectual, social development; forms the value attitude to the state, native land, Ukrainian culture, health, ability to creative expression, critical thinking and more. Emphasis is placed on the need to synchronize the basic provisions of preschool and primary education, as bringing the content, forms and methods of formation of preschoolers' competencies in line with the requirements for personality set by the reform of the New Ukrainian School. The purpose of the article is to determine the main aspects of synchronization of preschool education with primary for the holistic formation of the child's competencies. In the process of scientific research methods of analysis, synthesis, generalization, systematization, inferences and comparisons were used to determine the main competencies and their synchronization with such normative documents as the Basic component of preschool education and the State standard of primary education. The competencies defined by the Basic component of preschool education and the State standard of primary education, built in accordance with the requirements of the Concept of the new Ukrainian school, have been synchronized. In the process of comparative analysis it was noted that each of the competencies of the Basic component of preschool education is defined by the competence in the State standard of primary school, which characterizes the continuity and prospects of preschool and primary education. Since the leading activity in preschool is play, the basic component is the formation of game competence, and in the primary school the educational process is built through play.</jats:p

Musical and educational activities of Mykola Lysenko as a phenomenon of self-identification of the national culture

Formulation of the problem. In the globalized time-space of the 21st century, the musical heritage left by M.V. Lysenko motivates to comprehend at a new level the phenomenon of the creative universalism of the artist, the multiple manifestations of his musical-social, educational, ethnographic and composing activities. Given the importance of the choral singing for nurturing the national consciousness of young musicians, the role of M. Lysenko’s opera heritage for children and adolescents should be noted. The choice of the theme was actualized by the iconic premiere of M. Lysenko’s children’s opera called “Winter and Spring” (2017) at the Great Hall of Kharkiv National University of Arts named after I.P. Kotlyarevsky,performed by young performers, which coincided with honouring the memory of the great Kobzar (the 175th anniversary since his birthday). In particular, the orchestration was performed by Yelizar Pashchenko, the stage director – Sofia Melnikova; the conductor –the author of the article. Thus, M. Lysenko’s children’s opera is still relevant for young artists in terms of their professional and national self-growth. The purpose of the article is to systematize the manifestations of artistic universalism in the activities of M.V. Lysenko in the aspect of phenomenology of the creativity of the composer on the example of the genre of children’s opera. The object of the study is the Ukrainian music tradition; the subject – music-educational activity of M. Lysenko in the aspect of its actualization in the contemporary cultural and artistic space. The analysis of recent publications on the topic. The reflection of M.V. Lysenko’s creative heritage in its aspects was performed in the studies by the classics of Ukrainian studies (K. Kvitka (1986), M. Rylsky (1927), O. Pchilka (1913a, 1913b), L. Arhimovych, M. Gordiychuk (1992)), and by the modern scholars (L. Corniy (2011), S. Grytsa (2007)). One of the fundamental editions is the book-album called “Mykola Lysenko’s World. National identity, music and politics of Ukraine of the 19th– the beginning of the 20thcenturies»(compiled by T. Bulat and T. Filenko (2009)). However, there is no phenomenological approach to the master’s creative work in these sources. The presentation of the main material. M. Lysenko was a personality gifted with many talents, at that time he was presenting the figure of a universal personality – on the one hand, an intellectual, and on the other – an educator. He read in the original language the works by Russian, Polish, German, French writers (Dumas, Eugene Sue), independently studied the works by R. Schuman and R. Wagner, Y.S. Bach, performed virtuosic compositions by F. Liszt. The manifestations of the artistic universalism of M.V. Lysenko as a criterion of the composer’s activity in the light of the problem of self-identification of Ukrainian culture at the stage of its formation have been systematized. The composer’s outlook and aspects of his creative life have been characterized. Lysenko’s music-educational activities began the process of democratization of music education in Kyiv. So, in 1904 he opened the School of Drama and Music. He focused on the programs of Moscow and St. Petersburg Conservatories. Therefore, on the stage of the educational institution the authors of the modern version of the opera “Winter and Spring” take the ideas of the founder of the national musical culture. Their purpose was to preserve the holistic concept of the development of the musical form of the opera. The ancient folk intonations, the expressive and difficult in the technical performancesub-voices, the varied and original use of the fret, reflected in the melody of children’skolyadka (carols) and vesnyanka (spring songs), helped the young performers to achieve some level of the performing skills. It should be noted that the final choir (vesnyanka) “And it’s spring already, and it’s already good”, as well as the choral scenes of carolling and spring celebrations are in low demand in the modern choral performance and need to be popularized. For example, the choral scene that begins with the kolyadka called “Herod Is Damned” can be performed as a compulsory piece at children’s choral competitions in Ukraine. The opera is quite technically difficult to perform. Children’s mass scenes “cement” the opera’s musical material. The choir of the younger age children performed the first choral song “Go, Go, Let’s Meet”, built on the invocative intonation of the big tertiary, there are jumps on octave and the fifth; by means of harmonization, the composer gives a colourful sounding to the choir’s kolyadka and shchedrivka (New Year Ukrainian song). Conclusions. In the choral scene of the children’s opera called “Winter and Spring”, the composer applied such techniques as: the combination of shchedrivka and kolyadka in the choir “New Joy Began”; the techniques of folk polyphony: unison chants (vesnyanka “Cuckoo in the Meadow”), the tertiary doubles and octave thickenings (the ancient kolyadka “Herod Is Damned”); the original means of vocal-choral writing (the final choir “And it’s spring already, and it’s already good”). Thus, M. Lysenko’s creativity is filled, on the one hand, with the love to Ukrainian folklore, and on the other, with the perception of the European spiritual values of the music world, where Ukraine should take its rightful place. This is the phenomenon of self-identification of the professional activity of the great composer and figure of musical culture, which is inherited by the modern musicians of Kharkiv</jats:p

DERMAL ABSORPTION OF DIQUAT AND POTENTIAL OCCUPATIONAL RISK

The aim: The toxicological-hygienic assessment of dermal absorption of diquat in terms of potential risk of its bioavailability in professional use. Materials and methods: The object of the study was cutaneous exposure of diquat, determined in toxicological experiments of different duration (data of scientific literature) and at the stage of state testing of pesticide preparations based on diquat dibromide (data of a full-scale hygiene experiment, prognostic model of risk assessment), the technical concentrate of diquat dibromide (active substance content not less than 377 g / kg) contains relevant supplements, the content of which is regulated by the Food and Agriculture Organization. Results and conclusions: Due to the high risk of the diquat adverse effects affecting the personnel, general public and environment, the European Union has introduced administrative decisions to forbid plant protection products containing the diquat. Fulfillment of the conditions of the Association Agreement between Ukraine and the European Union indicates the need to develop common regulations and risk assessment methods aimed at ensuring high level of protection of human health and the environment.</jats:p