Community and law: identifying the locus of law in community

"Community and law approach" provides an illuminating insight into alternative legal orderings within a social unit. The comprehensiveness of legal systems within a community or a social unit, provides a suitable basis for a structural framework of alternative legal systems or Legal Pluralism, which is missing in the discourse on Legal Pluralism. "Identifying the locus of law within a community", provides us with an indication on how autopoetic a legal system can be within a social unit, taking into account the social rootedness of legal norms

A New Direction in Dark-Matter Complementarity: Dark-Matter Decay as a Complementary Probe of Multi-Component Dark Sectors

In single-component theories of dark matter, the $2\to 2$ amplitudes for dark-matter production, annihilation, and scattering can be related to each other through various crossing symmetries. These crossing relations lie at the heart of the celebrated complementarity which underpins different existing dark-matter search techniques and strategies. In multi-component theories of dark matter, by contrast, there can be many different dark-matter components with differing masses. This then opens up a new, "diagonal" direction for dark-matter complementarity: the possibility of dark-matter decay from heavier to lighter dark-matter components. In this work, we discuss how this new direction may be correlated with the others, and demonstrate that the enhanced complementarity which emerges can be an important ingredient in probing and constraining the parameter spaces of such models.Comment: 11 pages, LaTeX, 4 figure

Off-Diagonal Dark-Matter Phenomenology: Exploring Enhanced Complementarity Relations in Non-Minimal Dark Sectors

In most multi-component dark-matter scenarios, two classes of processes generically contribute to event rates at experiments capable of probing the nature of the dark sector. The first class consists of "diagonal" processes involving only a single species of dark-matter particle -- processes analogous to those which arise in single-component dark-matter scenarios. By contrast, the second class consists of "off-diagonal" processes involving dark-matter particles of different species. Such processes include inelastic scattering at direct-detection experiments, asymmetric production at colliders, dark-matter co-annihilation, and certain kinds of dark-matter decay. In typical multi-component scenarios, the contributions from diagonal processes dominate over those from off-diagonal processes. Unfortunately, this tends to mask those features which are most sensitive to the multi-component nature of the dark sector. In this paper, by contrast, we point out that there exist natural, multi-component dark-sector scenarios in which the off-diagonal contributions actually dominate over the diagonal. This then gives rise to a new, enhanced picture of dark-matter complementarity. In this paper, we introduce a scenario in which this situation arises and examine the enhanced picture of dark-matter complementarity which emerges.Comment: 17 pages, LaTeX, 2 figures. Replaced to match published versio

Adiponectin and Cardiac Hypertrophy in Acromegaly

Background. Adiponectin is an adipocytes-derived hormone which has been shown to possess insulin-sensitizing, antiatherogenic, and anti-inflammatory properties. In acromegaly, the data on adiponectin is contradictory. The relationship between adiponectin levels and cardiac parameters has not been studied.Objectives. The aim of this study was to find out how adiponectin levels were affected in acromegalic patients and the relationship between adiponectin levels and cardiac parameters.Material and Methods. We included 30 subjects (15 male, 15 female), diagnosed with acromegaly and 30 healthy (10 male, 20 female) subjects. Serum glucose, insulin, GH, IGF-1 and adiponectin levels were obtained and the insulin resistance of the subjects was calculated. Echocardiographic studies of the subjects were performed.Results. We determined that adiponectin levels were significantly higher in the acromegalic group than the control group. In the acromegalic group, there was no statistically significant relation between serum adiponectin and growth hormone (GH), or insulin-like growth factor-1 (IGF-1) levels (p = 0.3, p = 0.1). We demonstrated that cardiac function and structure are affected by acromegaly. IVST, PWT, LVMI, E/A ratio, DT, ET, IVRT, VPR, and LVESV values were increased and the results were statistically significant. In the acromegalic group, adiponectin levels were positively related with left ventricle mass index (LVMI) but this correlation was found to be statistically weak (p = 0.03). In our study, there was a positive correlation between VAI and LVM. We also could not find any correlation between VAI and adiponectin levels.Conclusions. Although insulin resistance and high insulin levels occur in active acromegaly patients, adiponectin levels were higher in our study as a consequence of GH lowering therapies. Our study showed that adiponectin levels may be an indicator of the cardiac involvement acromegaly. However, the usage of serum adiponectin levels in acromegalic patients as an indicator of cardiac involvement should be supported with other, wide, multi-centered studies

Central and peripheral corneal thickness measurement with Orbscan II and topographical ultrasound pachymetry

PURPOSE: To compare thickness measurements of the central 6.0 mm of the cornea obtained with the Orbscan(R) II topography system and topographical ultrasound pachymetry. SETTING: School of Optometry, University of Santiago de Compostela, Galicia, Spain. METHODS: In 24 right eyes, pachymetric measurements were taken at the center and 1.2 mm and 3.0 mm on the superior and inferior hemimeridians. A 1-sample t test was applied to assess the significance of the relationship between Orbscan II and ultrasound methods. The relationship between the 2 was assessed by analyzing regression and plotting the differences against the mean corneal thickness. Orbscan II data were analyzed in 3 ways: (1) without the application of an acoustic equivalent correction factor; (2) with a correction factor of 0.92, as recommended by the manufacturer; (3) with correction using the equations derived in this study. The data were systematically compared with those of ultrasound pachymetry. RESULTS: Before the correction factor was applied, the Orbscan II overestimated the corneal thickness at all locations, with the mean difference (48.15 microm +/- 33.74 [SD]) significantly different from zero (P .05). CONCLUSIONS: The acoustic equivalent correction factor proposed by the manufacturer to obtain corneal thickness measurements with the Orbscan II compared to those from ultrasound pachymetry was not valid for all corneal topography positions. Orbscan II measurements agreed better with those of ultrasound pachymetry when equations for the central and each peripheral location across the topography were applied