Towards Sustainable Water Solutions: Investigating Groundwater Possibility in Dindori District of Madhya Pradesh, India

Groundwater is a crucial resource, as approximately 45% of irrigation and around 80% of domestic water needs in India are fulfilled by groundwater reservoirs. Therefore, it is essential to determine where the probability of groundwater availability is high and where it is low. In areas with low probability, there is a need for the rapid development of recharge structures. GIS and remote sensing technology is a crucial tool for obtaining information about availability of ground water potential as well as finding suitable site for recharge structures. The investigation will involve geological surveys to understand the hydrogeological characteristics of the region, including aquifer properties, recharge mechanisms, and groundwater quality. Additionally, environmental impact assessments will be conducted to evaluate the sustainability of groundwater extraction and its potential implications on the surrounding ecosystems. Furthermore, socio-economic analyses will explore the existing water usage patterns, community needs, and stakeholders\u27 perspectives to develop inclusive and equitable groundwater management plans. "This study focuses on the Dindori district in Madhya Pradesh, India. There are different factors affecting groundwater recharge, including topography, slope, land use and land cover, drainage density, geology, soil distribution, rainfall, lineament, etc. Satellite images provide information about land use/land cover, geomorphology, and DEM delineate slope, drainage, and lineament. They are classified into different classes and assigned weights. ArcGIS software was used for data integration and weighted overlay analysis to create a groundwater potential map for the Dindori district. The groundwater potential map is categorized into five classes: \u27Excellent\u27 (0.01%), \u27Good\u27 (9.78%), \u27Moderate\u27 (70.04%), \u27Poor\u27 (19.97%), and \u27Very Poor/Nil\u27 (0.17%).

Effectiveness of different plant extracts against Galleria mellonella larvae in laboratory

The present investigation was undertaken to study the effectiveness of different plant extracts against Galleria mellonella larvae in laboratory. Acetone prepared extracts of leaves, stem, seed, root, husk of thirteen medicinal and healthy plants were used to examine their effects on the mortality of the greater wax moth Galleria mellonella larvae in laboratory.  Results revealed that only six plant extracts prepared with leaves and stem cause mortality of wax moth. Larval mortality was highest (93.33%) with husk prepared extract of P. psyllium followed by leaf prepared extract of H. sativum (80%), Raphanus sativus (73.33%), Linum usitatissimum (66.66%) Cucurbita moschata (46.66%) and Vicia sativa (46.66%). The larval mortality with stem/root/seed prepared extract was recorded highest in Hordeum sativum (73.33%) followed by Raphanus sativus (80%), Cucurbita moschata (60%)  Linum usitatissimum (53.33%) and Vicia sativa (40%) and found significant difference with the control (0.00%). There was no mortality of larvae was found in control and other remaining plant extract. Irrespective of the different plants, highest per cent mortality (52.22%) of wax moth larvae by stem/seed/ root prepared extract followed by leaf extract (48.66). Therefore, the plant extract of different plants were found effective against Galleria mellonella larvae

Morin: A Powerful Potential Flavonoid for Human

Objective: A bioflavonoid obtained from plants in the Moraceae family, morin exhibits strong pharmacological potential because of its hepatoprotective, neuroprotective, cardioprotective, anti-inflammatory, antioxidant, and anticancer effects. It is a promising therapeutic agent for diseases like diabetes, cancer, and neurodegenerative disorders because of its low toxicity and capacity to alter important cellular signaling pathways like Nrf2/HO-1 and EGFR. Data Sources: Its antioxidant mechanism effectively reduces oxygen species that are reactive and oxidative damage through the Nrf2/HO-1 pathway, potentially preventing neurodegenerative diseases. Study Selection: The effectiveness of morin has been proven in both Parkinson\u27s disease and colitis models, highlighting its neuroprotective and anti-inflammatory properties, anti-oxidant, cardioprotective, anti-diabetic, synergistic effects. Morin\u27s anti-inflammatory properties, whereby it reduces glial activation and improves tissue recovery. Summary of Contents of the Article: Morin acts as a non-competitive inhibitor of PTP1B in anti-diabetic studies, thereby enhancing insulin sensitivity. Its anti-cancer effects consist in increasing death by caspase activation and blocking of metastases in breast cancer. Morin also guards against liver damage, neurotoxicity, and myocardial ischemia-reperfusion injury. Conclusion: Although morin has low toxicity and great tolerance, the exact molecular mechanisms of it are yet unknown and demand more in vitro and in vivo research. Establishing safe dosage, efficacy, and dose-response relationships requires clinical trials, which also help to open the path for morin\u27s inclusion into dietary supplements and drug development for chronic diseases. Keywords: Caspase activation, Flavonoid, Hepatoprotective, Morin, Reactive oxygen species

Ossified pterygo-spinous ligament: incidence and clinico-anatomical relevance in the adult human skulls of North India

Study of skulls has attracted the attention of anatomists since ages and sporadic attempts have been made to study skulls from time-to-time. Talking about the pterygoid processes of sphenoid bone, the irregular posterior border of lateral pterygoid plate usually presents, towards its upper part, a pterygo-spinous process, from which the pterygo-spinous ligament extends backwards and laterally to the spine of sphenoid. This ligament sometimes gets ossified as pterygo-spinous bar and a foramen is then formed named pterygo-spinous foramen, for the passage of muscular branches of mandibular nerve. The present study was undertaken to observe the incidence and status of pterygo-spinous bony bridge and foramen, its variations and clinical relevance in the adult human skulls of North India. For this purpose, 50 skulls were observed, pterygo-spinous bars were found to be present in 7 skulls, out of which completely ossified pterygo-spinous bony bridges were present in 2 skulls while 5 skulls had incompletely ossified pterygo-spinous ligaments. Such variations are of clinical significance for radiologists, neurologists, maxillo-facial & dental surgeons and anaesthetists, too

Anatomical description and clinical significance of unilateral triheaded sternocleidomastoid muscle

Objective of this report is to observe and report unusual pattern of origin of sternal and clavicular heads of Sternocleidomastoid (SCM). An embryological insight into the possible causes for present anomaly is elucidated. The neck region of an adult male cadaver during gross anatomy teaching program. An abnormal Sternocleidomastoid (SCM) was observed while dissecting the neck region of an adult. Additional clavicular head of SCM muscle were found on the right side. The accessory clavicular head coursed deep to the sternal head whereas the some fibres of main clavicular head joined the accessory belly and together they fused with the main sternal head of SCM. There was another slip arising from sternal head and merge with deep cervical fascia near base of mandible. The topographical anatomy of SCM is extremely important, particularly because it serves as a useful surgical landmark and its relation to crucial neuro-vascular structures of the neck. The usage of SCM in reconstruction operations for covering defects is discussed. A detailed knowledge of the anatomy of SCM proves vital for radiological studies of the neck

ConfSys 4: An Advanced Conference Management System with Automatic Semantic Header Generation

ConfSys, a conference management system, has been used for over 15 years to manage a number of international academic conferences, such as C3S2E, IDEAS, and ICCM. It supports multi-event, multi-track conferences with a large number of user participation and submissions. It provides essential services such as setting up a conference, user sign-ups, call for papers, paper submissions, paper auction, paper allocation and review, blind debate, paper decision, author registration, final version submissions, automatic session management, presentation uploads, program generation, managing event sessions and electronic proceedings creation to efficiently manage and support the running of academic conferences and journals. This thesis presents the fourth iteration in the ConfSys system to further accelerate enhancements and to incorporate new features keeping in sync with recent technological advancements. It presents new approach for Automatic Semantic Header Generation (ASHG 2) in Information Retrieval from academic documents such as research papers. ConfSys4 includes modules for document processing, information retrieval, and document classification. Document processing involves conversion of PDF documents to XML-formatted documents. Information retrieval involves extraction of paper-related details such as title, abstract, keywords, author names, emails, organizations, locations, affiliations, and author references present within the document. The extraction of author-related details ensures verification of the author metadata and references section for the submitted document. Document classification involves extraction of important subject headings (keywords) based on the contents of the submitted document. Thus, improving the paper submission, single/double/triple-blind review, and paper allocation process by reducing manual data entry by users. Additionally, ConfSys4 includes improvements to existing features, such as adding automatic reminder emails to program committee members for updating their topics of interest for improved paper allocation and using entity matching technique for author pairs identification with conflicting interests. Furthermore, the PayPal payment interface is improved to include a standard checkout feature for payments and PDF document generation for the final program, invoice, and payment receipt for user registration to events. These improvements in ConfSys4 ensure consistent metadata generation for papers, improved transparency, ease of usability, and operability for organizing committee members, authors, and system users of the ConfSys system

Cross-sectional study on accidental occupational exposures amongst urban slum-based private medical practitioners

Background:This cross-sectional, complete enumeration study was conducted in an urban slum to determine the frequency of occupational exposure of private medical practitioners to patient body fluids and the remedial measures adopted following such events and also to examine their high-risk practices, personal protective measures, immunisation and training status in relation to occupational exposures.Methods: After Institutional Ethics Committee approval, private medical practitioners practising for ≥ 1 year in the locality who gave written informed consent were interviewed in their own clinics using a pre-tested formatted questionnaire.Results: Of the 108 respondents interviewed, the majority were non-allopathic, male practitioners. The speciality-wise and gender-wise differences in training in occupational exposure were not significant (p=0.135). Prior to disposal, 10.18% cut needles while 26.85% disinfected needles with 1% hypochlorite solution (p=0.0001). 50.93% never bent or recapped needles (p=0.0008). Only 19.44% regularly used gloves while examining patients (p=0.0039). 41.66% were completely unimmunised against Hepatitis B (p=0.004), while only one female non-allopathic practitioner (0.92%) had taken complete immunisation against tetanus (p<0.05). Of the 7.41% respondents who had history of needle stick injuries, only one female non-allopathic practitioner had reported occupational exposure. Those unaware about the need for post-exposure prophylaxis for occupational exposure and that anti-retroviral therapy was part of post-exposure prophylaxis constituted 87.96% and 95.37%, respectively.Conclusions: Reporting of occupational exposure, complete immunisation against hepatitis B and tetanus and use of personal protection was inadequate. Specialised hands-on training ought to be an integral component of continuing medical education for private medical practitioners.

Histopathological Changes in Kidneys of Developing Chick Embryo on Exposure to Lixisenatide

Chick embryo is one of the most commonly used animals to study the adverse effects of various drugs for research purpose. Currently, type 2 diabetes mellitus is treated using the medication lixisenatide. Therapeutically, is thought to be superior to other GLP1 receptor antagonists for the treatment of type 2 diabetes. To understand the adverse effects of lixisenatide on kidney of developing chick embryo