A study of the high-inclination population in the Kuiper belt - II. The Twotinos

As the second part of our study, in this paper we proceed to explore the dynamics of the high-inclination Twotinos in the 1:2 Neptune mean motion resonance (NMMR). Depending on the inclination $i$, we show the existence of two critical eccentricities $e_a(i)$ and $e_c(i)$, which are lower limits of the eccentricity $e$ for the resonant angle $\sigma$ to exhibit libration and asymmetric libration, respectively. Accordingly, we have determined the libration centres $\sigma_0$ for inclined orbits, which are strongly dependent on $i$. With initial $\sigma=\sigma_0$ on a fine grid of $(e, i)$, the stability of orbits in the 1:2 NMMR is probed by 4-Gyr integrations. It is shown that symmetric librators are totally unstable for $i\ge30^{\circ}$; while stable asymmetric librators exist for $i$ up to $90^{\circ}$. We further investigate the 1:2 NMMR capture and retention of planetesimals with initial inclinations $i_0\le90^{\circ}$ in the planet migration model using a time-scale of $2\times10^7$ yr. We find that: (1) the capture efficiency of the 1:2 NMMR decreases drastically with the increase of $i_0$, and it goes to 0 when $i_0\ge60^{\circ}$; (2) the probability of discovering Twotinos with $i>25^{\circ}$, beyond observed values, is roughly estimated to be $\le0.1$ per cent; (3) more particles are captured into the leading rather than the trailing asymmetric resonance for $i_0\le10^{\circ}$, but this number difference appears to be the opposite at $i_0=20^{\circ}$ and is continuously varying for even larger $i_0$; (4) captured Twotinos residing in the trailing resonance or having $i>15^{\circ}$ are practically outside the Kozai mechanism, like currently observed samples.Comment: 13 pages, 10 figures, Accepted by MNRAS. Comments welcome

Formation and transformation of the 3:1 mean-motion resonance in 55 Cancri System

We report in this paper the numerical simulations of the capture into the 3:1 mean-motion resonance between the planet b and c in the 55 Cancri system. The results show that this resonance can be obtained by a differential planetary migration. The moderate initial eccentricities, relatively slower migration and suitable eccentricity damping rate increase significantly the probability of being trapped in this resonance. Otherwise, the system crosses the 3:1 commensurability avoiding resonance capture, to be eventually captured into a 2:1 resonance or some other higher-order resonances. After the resonance capture, the system could jump from one orbital configuration to another one if the migration continues, making a large region of the configuration space accessible for a resonance system. These investigations help us understand the diversity of resonance configurations and put some constrains on the early dynamical evolution of orbits in the extra-solar planetary systems.Comment: 6 pages with 2 figures. Submitted for publication in the proceedings of IAU Symposium No.249. A paper telling much more details than this paper is under preparin

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis

Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors. Neurogenin 1 and MASH1 activate PK2 transcription by binding to E-box motifs on the PK2 promoter with the same set of E-boxes critical for another pair of bHLH factors, CLOCK and BMAL1, in the regulation of circadian clock. Our results establish PK2 as a common functional target gene for different bHLH transcriptional factors in mediating their respective functions

Prevalence of Antibiotic Resistome in Ready-to-Eat Salad

Ready-to-eat salad harbors microorganisms that may carry various antibiotic resistance genes (ARGs). However, few studies have focused on the prevalence of ARGs on salad, thus underestimating the risk of ARGs transferring from salad to consumers. In this small-scale study, high-throughput quantitative PCR was used to explore the presence, prevalence and abundance of ARGs associated with serving salad sourced from two restaurant types, fast-food chain and independent casual dining. A total of 156 unique ARGs and nine mobile genetic elements (MGEs) were detected on the salad items assessed. The abundance of ARGs and MGEs were significantly higher in independent casual dining than fast-food chain restaurants. Absolute copies of ARGs in salad were 1.34 × 107 to 2.71 × 108 and 1.90 × 108 to 4.87 × 108 copies per g salad in fast-food and casual dining restaurants, respectively. Proteobacteria, Bacteroidetes, Actinobacteria, and Firmicutes were the dominant bacterial phyla detected from salad samples. Pseudomonas, Acinetobacter, Exiguobacterium, Weissella, Enterobacter, Leuconostoc, Pantoea, Serratia, Erwinia, and Ewingella were the 10 most dominant bacterial genera found in salad samples. A significant positive correlation between ARGs and MGEs was detected. These results integrate knowledge about the ARGs in ready-to-eat salad and highlight the potential impact of ARGs transfer to consumers.</p