8,354 research outputs found

    Armed T cells with CAR for cancer immunotherapy

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    Probing the physics of newly born magnetars through observation of superluminous supernovae

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    The central engines of some superluminous supernovae (SLSNe) are generally suggested to be newly born fast rotating magnetars, which spin down mainly through magnetic dipole radiation and gravitational wave emission. We calculate the magnetar-powered SLSNe light curves (LCs) with the tilt angle evolution of newly born magnetars involved. We show that, depending on the internal toroidal magnetic fields Bˉt{\bar B}_{\rm t}, the initial spin periods PiP_{\rm i}, and the radii RDUR_{\rm DU} of direct Urca (DU) cores of newly born magnetars, as well as the critical temperature TcT_{\rm c} for 3P2^3P_2 neutron superfluidity, bumps could appear in the SLSNe LCs after the maximum lights when the tilt angles grow to π/2\pi/2. The value of TcT_{\rm c} determines the arising time and the relative amplitude of a bump. The quantity RDUR_{\rm DU} can affect the arising time and the luminosity of a bump, as well as the peak luminosity of a LC. Moreover, it is interesting that a stronger Bˉt{\bar B}_{\rm t} will lead to both a brighter peak and a brighter bump in a LC. While keeping other quantities unchanged, the bump in the LC disappears for the magnetar with smaller PiP_{\rm i}. We suggest that, once the SLSNe LCs with such kinds of bumps are observed, by fitting these LCs with our model, not only BdB_{\rm d} and PiP_{\rm i} of newly born magnetars but also the crucial physical quantities Bˉt{\bar B}_{\rm t}, RDUR_{\rm DU}, and TcT_{\rm c} could be determined. Nonobservation of SLSNe LCs with such kinds of bumps hitherto may already put some (\textit{though very rough}) constraints on Bˉt{\bar B}_{\rm t}, PiP_{\rm i}, RDUR_{\rm DU}, and TcT_{\rm c}. Therefore, observation of SLSNe LCs may provide a new approach to probe the physics of newly born magnetars.Comment: 9 pages, 4 figures, to appear in PR

    Guest Editorial: Nonlinear Optimization of Communication Systems

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    Linear programming and other classical optimization techniques have found important applications in communication systems for many decades. Recently, there has been a surge in research activities that utilize the latest developments in nonlinear optimization to tackle a much wider scope of work in the analysis and design of communication systems. These activities involve every “layer” of the protocol stack and the principles of layered network architecture itself, and have made intellectual and practical impacts significantly beyond the established frameworks of optimization of communication systems in the early 1990s. These recent results are driven by new demands in the areas of communications and networking, as well as new tools emerging from optimization theory. Such tools include the powerful theories and highly efficient computational algorithms for nonlinear convex optimization, together with global solution methods and relaxation techniques for nonconvex optimization

    Adaptive computation of multiscale entropy and its application in EEG signals for monitoring depth of anesthesia during surgery

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    Entropy as an estimate of complexity of the electroencephalogram is an effective parameter for monitoring the depth of anesthesia (DOA) during surgery. Multiscale entropy (MSE) is useful to evaluate the complexity of signals over different time scales. However, the limitation of the length of processed signal is a problem due to observing the variation of sample entropy (SE) on different scales. In this study, the adaptive resampling procedure is employed to replace the process of coarse-graining in MSE. According to the analysis of various signals and practical EEG signals, it is feasible to calculate the SE from the adaptive resampled signals, and it has the highly similar results with the original MSE at small scales. The distribution of the MSE of EEG during the whole surgery based on adaptive resampling process is able to show the detailed variation of SE in small scales and complexity of EEG, which could help anesthesiologists evaluate the status of patients.The Center for Dynamical Biomarkers and Translational Medicine, National Central University, Taiwan which is sponsored by National Science Council (Grant Number: NSC 100-2911-I-008-001). Also, it was supported by Chung-Shan Institute of Science & Technology in Taiwan (Grant Numbers: CSIST-095-V101 and CSIST-095-V102). Furthermore, it was supported by the National Science Foundation of China (No.50935005)

    Cohort records study of 19,655 women who received postabortion care in a tertiary hospital 2010–2013 in China : what trends can be observed?

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    The retrospective cohort epidemiological study was to investigate the characteristics of women who underwent induced abortion. Data were retrospectively collected from women who underwent induced abortions () at the Xiamen Maternity and Child Health Care Hospital (2010–2013). The characteristics of women who underwent induced abortions included mean age, unmarried status, no previous deliveries, first pregnancy, ≥2 abortions including the current one, and a history of caesarian section. From 2010 to 2013, mean age increased and declines were observed in the ratio of induced abortions to live births, the proportion of induced abortions among women of 15–24 years, those who were unmarried, had their first pregnancy, or had no history of delivery. However, the rates of induced abortions increased among women who were lactating, had a history of caesarian section, or had an interpregnancy interval of <6 months. This snapshot of induced abortions in China might suggest that the numbers are increasing but the ratio to live births has fallen. Methods should be improved to prevent unwanted pregnancies and reduce the number of induced abortions in China. It must be emphasized that differences in mentality and culture between countries might limit the representativeness of these results
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