733 research outputs found
Dissipative dynamics in a tunable Rabi dimer with periodic harmonic driving
Recent progress on qubit manipulation allows application of periodic driving
signals on qubits. In this study, a harmonic driving field is added to a Rabi
dimer to engineer photon and qubit dynamics in a circuit quantum
electrodynamics device. To model environmental effects, qubits in the Rabi
dimer are coupled to a phonon bath with a sub-Ohmic spectral density. A
non-perturbative treatment, the Dirac-Frenkel time-dependent variational
principle together with the multiple Davydov D {\it Ansatz} is employed to
explore the dynamical behavior of the tunable Rabi dimer. In the absence of the
phonon bath, the amplitude damping of the photon number oscillation is greatly
suppressed by the driving field, and photons can be created thanks to
resonances between the periodic driving field and the photon frequency. In the
presence of the phonon bath, one still can change the photon numbers in two
resonators, and indirectly alter the photon imbalance in the Rabi dimer by
directly varying the driving signal in one qubit. It is shown that qubit states
can be manipulated directly by the harmonic driving. The environment is found
to strengthen the interqubit asymmetry induced by the external driving, opening
up a new venue to engineer the qubit states
Practical Research on the Dual River Leaders System in the Context of Watershed Governance : A case study of Guiyang city, Guizhou province
This study focuses on the Dual River Leaders System, which can improve the water environment and combat the increasing basin pollution in China. It was born in the reform of the government's internal administrative system, and developed during the process of seeking cooperation between government and nongovernment. In particular, this study investigates the Dual River Leaders System in Guiyang City, Guizhou Province, where it was implemented in 2010, ahead of the rest of the country. We examined the changes over time through participatory survey methods and participation in practice as an environmental volunteer. This study discusses not only the improvement of water pollution but also the watershed governance of multi-subjects from the perspective of the local community. Moreover, we present new insights that challenge the inherent structure of China's environmental governance. We found that the Governmental River Leader System and the Non-Governmental River Leader System play important roles and have a complementary relationship. In addition, the Non-governmental River Leader System centers on the Civilian River Leaders who composed of intellectuals. In the process of continuous exploration, selecting suitable individuals from local village residents to serve as Civilian Environmental Supervisors has not only helped resolve regional conflicts but has also increased the environmental awareness of local residents. Thus gradually established a Watershed Governance Mode. The Non-Governmental River Leader System considers the relationship between nature and human beings and creates interactions between individuals that change the environmental consciousness and behavioral habits of local residents, while also fundamentally improving pollution. Furthermore, it tries to protect the environment of the local river basin by promoting cooperation among nongovernmental entities. Therefore, the Dual River Leaders System is not imitated Japan, Europe, and the United States, as a means of civilian participation, but it can empower local residents to participate in Watershed Governance, and create a new kind of "Chinese-style civilian participation." In addition, the Dual River Leaders System has played a critical role in civic behavior. The fi ndings of this study suggest that its implementation in Guiyang City is favorable for the development of Dual River Leaders Systems throughout China
Embedding Generalized Semantic Knowledge into Few-Shot Remote Sensing Segmentation
Few-shot segmentation (FSS) for remote sensing (RS) imagery leverages
supporting information from limited annotated samples to achieve query
segmentation of novel classes. Previous efforts are dedicated to mining
segmentation-guiding visual cues from a constrained set of support samples.
However, they still struggle to address the pronounced intra-class differences
in RS images, as sparse visual cues make it challenging to establish robust
class-specific representations. In this paper, we propose a holistic semantic
embedding (HSE) approach that effectively harnesses general semantic knowledge,
i.e., class description (CD) embeddings.Instead of the naive combination of CD
embeddings and visual features for segmentation decoding, we investigate
embedding the general semantic knowledge during the feature extraction
stage.Specifically, in HSE, a spatial dense interaction module allows the
interaction of visual support features with CD embeddings along the spatial
dimension via self-attention.Furthermore, a global content modulation module
efficiently augments the global information of the target category in both
support and query features, thanks to the transformative fusion of visual
features and CD embeddings.These two components holistically synergize general
CD embeddings and visual cues, constructing a robust class-specific
representation.Through extensive experiments on the standard FSS benchmark, the
proposed HSE approach demonstrates superior performance compared to peer work,
setting a new state-of-the-art
Like Humans to Few-Shot Learning through Knowledge Permeation of Vision and Text
Few-shot learning aims to generalize the recognizer from seen categories to
an entirely novel scenario. With only a few support samples, several advanced
methods initially introduce class names as prior knowledge for identifying
novel classes. However, obstacles still impede achieving a comprehensive
understanding of how to harness the mutual advantages of visual and textual
knowledge. In this paper, we propose a coherent Bidirectional Knowledge
Permeation strategy called BiKop, which is grounded in a human intuition: A
class name description offers a general representation, whereas an image
captures the specificity of individuals. BiKop primarily establishes a
hierarchical joint general-specific representation through bidirectional
knowledge permeation. On the other hand, considering the bias of joint
representation towards the base set, we disentangle base-class-relevant
semantics during training, thereby alleviating the suppression of potential
novel-class-relevant information. Experiments on four challenging benchmarks
demonstrate the remarkable superiority of BiKop. Our code will be publicly
available
Inhibition of fast axonal transport by pathogenic SOD1 involves activation of p38 MAP kinase
© The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in PLoS ONE 8 (2013): e65235, doi:10.1371/journal.pone.0065235.Dying-back degeneration of motor neuron axons represents an established feature of familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 (SOD1) mutations, but axon-autonomous effects of pathogenic SOD1 remained undefined. Characteristics of motor neurons affected in FALS include abnormal kinase activation, aberrant neurofilament phosphorylation, and fast axonal transport (FAT) deficits, but functional relationships among these pathogenic events were unclear. Experiments in isolated squid axoplasm reveal that FALS-related SOD1 mutant polypeptides inhibit FAT through a mechanism involving a p38 mitogen activated protein kinase pathway. Mutant SOD1 activated neuronal p38 in mouse spinal cord, neuroblastoma cells and squid axoplasm. Active p38 MAP kinase phosphorylated kinesin-1, and this phosphorylation event inhibited kinesin-1. Finally, vesicle motility assays revealed previously unrecognized, isoform-specific effects of p38 on FAT. Axon-autonomous activation of the p38 pathway represents a novel gain of toxic function for FALS-linked SOD1 proteins consistent with the dying-back pattern of neurodegeneration characteristic of ALS.Support was provided by 2007/2008 Marine Biological Laboratory summer fellowships and NIH (NS066942A) grants to GM; Howard Hughes Medical Institute-USE Grant #52006287 to Hunter College of CUNY (LM); Muscular Dystrophy Association (MDA) and NIH (R01NS44170) grants to LJH; MDA and NIH (NS23868, NS23320, NS41170) grants to STB; NIH grant MH066179 to GB; NIH grants R01AG031311 and R01NS055951 to DMW; NIH (U01NS05225, R01NS050557, 1RC1NS068391, 1RC2NS070342) grants to RHB; R01NS067206 to DAB; ALS Association grants to GM, AT, RHB, and STB; and ALS/CVS Therapy Alliance grants to RHB, GM, AT, LJH, and DAB. RHB and AT received support from the Angel Fund. RHB also received support from the DeBourgknecht Fund for ALS Research, P2ALS and Project ALS
Research progress on the correlation between platelet aggregation and tumor progression
Platelets are generally considered as the main
functional unit of the coagulation system. However,
more and more studies have confirmed that platelets also
have an important relationship with tumor progression.
Tumor cells can utilize platelets to promote their own
infiltration and hematogenous metastasis, and platelets
are activated and aggregated in this process. Therefore,
platelet aggregation may be a concomitant marker of
tumor progression. This is of great significance for
predicting tumor metastasis before timely treatments
Optimal wholesale price and technological innovation under dual credit policy on carbon emission reduction in a supply chain
The adoption of new energy vehicles (NEVs) can effectively reduce vehicle exhaust emissions and achieve carbon peaking and carbon neutrality goals in the transportation sector. To facilitate the development of NEVs, the Chinese government issued the dual credit policy (DCP). However, whether the DCP can promote the technological innovation of NEVs and effectively reduce carbon emissions in the transportation sector remains to be studied. This study constructed the decision-making model of NEVs under the DCP and obtained the optimal strategy to study the impact of the DCP on carbon emissions. Furthermore, we constructed a bargaining game model based on an alliance strategy to demonstrate the coordination of the NEV supply chain. The results showed that implementing the DCP can effectively reduce carbon emissions in the transportation field. The higher the technological innovation credit coefficient or credit price, the more significant the DCP’s incentive effect on reducing carbon emissions. Decentralized decision-making weakens the DCP’s incentive effect on reducing carbon emissions. The bargaining game based on alliance negotiation can enable independent companies to achieve carbon emission reduction when making centralized decisions so that the DCP’s incentive effect on reducing carbon emissions is optimized. The alliance between manufacturers is not to increase profits but to enhance their product advantages. However, suppliers can gain higher profits by participating in the alliance, which provides a theoretical reference for the alliance’s cooperation in decision-making
KidneyRegNet: A Deep Learning Method for 3DCT-2DUS Kidney Registration during Breathing
This work proposed a novel deep registration pipeline for 3D CT and 2D U/S
kidney scans of free breathing, which consists of a feature network, and a
3D-2D CNN-based registration network. The feature network has handcraft texture
feature layers to reduce the semantic gap. The registration network is
encoder-decoder structure with loss of feature-image-motion (FIM), which
enables hierarchical regression at decoder layers and avoids multiple network
concatenation. It was first pretrained with retrospective datasets cum training
data generation strategy, then adapted to specific patient data under
unsupervised one-cycle transfer learning in onsite application. The experiment
was on 132 U/S sequences, 39 multiple phase CT and 210 public single phase CT
images, and 25 pairs of CT and U/S sequences. It resulted in mean contour
distance (MCD) of 0.94 mm between kidneys on CT and U/S images and MCD of 1.15
mm on CT and reference CT images. For datasets with small transformations, it
resulted in MCD of 0.82 and 1.02 mm respectively. For large transformations, it
resulted in MCD of 1.10 and 1.28 mm respectively. This work addressed
difficulties in 3DCT-2DUS kidney registration during free breathing via novel
network structures and training strategy.Comment: 15 pages, 8 figures, 9 table
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