342 research outputs found
Computer simulation of the microstructure and rheology of semi-solid alloys under shear
The rheological behavior of metallic alloys containing both solid and liquid
phases is investigated in the low solid fraction range (<50%). This behavior
depends on both the solid fraction and the shear rate. The concept of Effective
Volume Fraction (EVF) is used to decorrelate the influence of these two
parameters. At high shear rate the slurry behaves like a suspension of hard
spheres, whereas at lower shear rate, particles tend to aggregate in clusters,
entrapping liquid and thus, increasing the EVF and the viscosity. A lattice
model is introduced to simulate the aggregation / break-up processes within a
slurry under shear. When the steady state is reached, the entrapped liquid
fraction is calculated, leading to a viscosity estimation. Simulation results
for the viscosity and 3D cluster structure are in good agreement with
experimental results.Comment: 30 pages, 17 figures, to be published in Acta Mate
Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL).
Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH). Patients typically present with prominent constitutional (B) symptoms, generalized lymphadenopathy, hepatosplenomegaly, cytopenias, and rash. Here we present a case of a 62-year-old male with progressive cervical adenopathy, fevers and weight loss presenting with extreme polyclonal plasmacytosis and high plasma EBV viral load. While the initial presentation appeared to mimic plasma cell leukemia or severe infection, lymph node biopsy and bone marrow biopsy confirmed a diagnosis of AITL. This case highlights the heterogeneity of the clinical presentation of AITL to enable physicians to more promptly recognize, diagnose and initiate treatment
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