An Introduction to Book Staying Ok

Over the last two decades, a change has occurred in the paradigm of the development model, especially individual and social development, and the theoretical model of dynamic human training has been attracting considerable interest since then. Indeed, humans and their needs were viewed from a different angle, and the communities set it as their goal to educate and train psychologically and socially good/OK humans. Thomas A. Harris, an American author, is one of the noted psychiatrists who has researched this subject for several decades. He has written several books on the good status and the good human. He believes that good training bred good status. This article firstly provides a short introduction about the book, and then in the second part, the Transactional Analysis Theory is introduced, and then the structure and content of the book are mentioned in the third part. In the rest of the paper, the criticisms and evaluation of the book are presented in two sub-sections (a) evaluation of form and (b) evaluation of the content. In the final section of the paper, the conclusion of the book is presented

Synthesis and characterization of Co-Zeolite nanocomposite: electrocatalytic oxidation of methionine

A cobalt-zeolite (CoY) nanocomposite was prepared and used as a modifier for construction of a carbon paste electrode (CoY/CPE) and it was applied for the determination of Methionine (Met). The surface morphology of the nanocomposite was characterized by X-ray diffraction(XRD), field emission scanning electron microscopy(FESEM), Energy dispersive X-ray analysis(EDX). Particle size of the prepared CoY was in the range between 31 nm and 64 nm. Electrochemical response characteristics of the modified electrode toward Met. were investigated by Cyclic Voltammetry(CV) and Differential Pulse Voltammetry(DP) in a 0.1 M phosphate buffer pH 6.2. A possible mechanism was proposed for the electrochemical response of the electrode toward Met. The electrode showed a suitable linear calibration curve in the concentration range of 3.5×10-7 – 5.5×10-6 mol L-1. The detection limit of the electrode(LOD) and quantification (LOQ) were calculated 9.1×10-8 mol L-1 and 1.3×10-7 mol L-1. Effect of different factors on the response of the electrode such as pH, modifier, electrolyte and scan rate was also studied. It was successfully applied for the determination of Met in serum samples. also the amount of %RSD for evaluation of repeatability and reproducibility of the proposed sensor was obtained 0.13%

Neurodegenerative Diseases and Autophagy

Most neurodegenerative diseases are characterized by the accumulation of aggregated proteins within neurons. These aggregate-prone proteins cause toxicity, a phenomenon that is further exacerbated when there is defective protein clearance. Autophagy is an intracellular clearance pathway that can clear these protein aggregates and has been shown to be beneficial in the treatment of neurodegenerative diseases in a variety of model systems. Here, we introduce the key components of the autophagy machinery and signaling pathways that control this process and discuss the evidence that autophagic flux may be impaired and therefore a contributing factor in neurodegenerative disease pathogenesis. Finally, we review the use of autophagy upregulation as a therapeutic strategy to treat neurodegenerative disorders

<i>Cis</i> P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae

Induction of the cis form of phosphorylated tau (cis P-tau) has previously been shown to occur in animal models of traumatic brain injury (TBI), and blocking this form of tau using antibody was beneficial in a rodent model of severe TBI. Here the authors show that cis P-tau induction is a feature of several different forms of TBI in humans, and that administration of cis P-tau targeting antibody to rodents reduces or delays pathological features of TBI

Relationship_of_economic_and_environmental.pdf

Since time immemorial, earthen architecture has been prevalent in Yazd; however, in spite of its merits and benefits, tendency for it has decreased over recent decades. The main objective of this research is to clarify the relationship of economic and environmental factors with the acceptance of newly built earthen houses. The research is a cross-sectional study conducted through a survey method. The sample population consisted of 145 young educated couples in Yazd selected based on the Cochran formula and through a multi-stage cluster sampling procedure. The results showed that the acceptance of newly built earthen houses among the respondents was higher than average. The perceived usefulness of this architecture in terms of both economic and environmental factors had a positive and significant correlation with the acceptance of that, while none of the demographic variables associated with acceptance. Using the regression model, environmental and then economic factors were found to account for 39 percent of the variance for the acceptance of the earthen architecture. According to these results, it seems that taking environmental and economic factors into consideration can affect people's interest and their acceptance of newly built earthen houses. In this regard, certain architectural solutions are presented in the paper. This research findings provide motivation for further and broader studies in this field

A Survey of Factors Related to Marital Satisfaction among Married Women in Taft City, Iran

Background: The foundation of a healthy community is based on the healthy communication between family members. In this regard, marital satisfaction is one of the important factors in strengthening the family relationships, which can be affected by the type of marriage as well as the family demographic and cultural components.&#x0D; Methods: This study was conducted on 120 married women in Taft. Participants were selected by systematic sampling method using Cochran formula. The research tools were Enrique Marital Satisfaction Questionnaire (1998) and a researcher-made questionnaire. Validity of the latter questionnaire was assessed using face validity and its reliability was confirmed by Cronbach’s alpha.&#x0D; Results: According to the results, the marital satisfaction of married women was in moderate level. Moreover, marital satisfaction was higher among the villagers (P-value = 0.006), non-familial marriages (P-value = 0.006), and housewives (P-value = 0.042) than other groups. Considering the type of marriage, forced marriage (P-value ≤ 0.50) showed a significant relationship with lack of life satisfaction; in other words, a higher degree of satisfaction was observed in unforced marriages. According to the regression analysis, four variables of couple’s age differences, education level differences, duration of marriage, and type of marriage (forced and unforced) explained about 43.5 percent of the dependent variable variations.&#x0D; Conclusion: Eventually, increase in the education level of couples decreased their life satisfaction; whereas, marital satisfaction increased by increase of age, duration of marriage, number of children. Moreover, marital satisfaction was lower in forded marriages.</jats:p