Gingival conditioning

O condicionamento gengival objetiva melhorar o formato do rebordo residual, em altura e espessura, proporcionando espaço e desenho adequado para o perfil de emergência do pôntico que será instalado naquele sítio. A obtenção de um rebordo em arco côncavo e de papilas interdentais possibilita a confecção de Próteses Parciais Fixas estéticas, funcionais e biocompatíveis. Este trabalho apresenta um caso clínico em que foi realizado condicionamento gengival através de procedimento cirúrgico associado à utilização de provisórios, alcançando-se os objetivos estéticos, funcionais e de biocompatibilidade desejados. _______________________________________________________________________________________ RESUMENEl acondicionamiento gingival tiene por objetivo mejorar la forma del reborde residual, en altura y grosor, proporcionando espacio y conformación adecuados para el perfil de emergência del póntico que se instalará en aquella zona. La obtención de um reborde en arco cóncavo y con papilas interdentales possibilita la confección de Prótesis Parciales Fijas estéticas, funcionales y biocompatibles. Ese trabajo presenta un caso clínico en el que se realizó el acondicionamiento gingival mediante un procedimiento quirúrgico asociado a la utilización de provisorios, lo cual permitió alcanzar los objetivos deseados: estéticos, funcionales y de biocompatibilidad

PulsatioMech: An Open-Source MATLAB Toolbox for Seismocardiography Signal Processing

This paper summarizes and presents PulsatioMech: an open-source MATLAB toolbox for seismocardiography (SCG) signal processing. The toolbox may be found here: https://github.com/nzavanelli/SCG_master_toolbox PulsatioMech is currently under development as a common tool to promote new studies and discoveries in the use of cardiac mechanical signal for wearable health monitoring. This toolbox is designed to assist users in analyzing SCG signals without the need to devote significant effort into signal processing and coding tasks. Simultaneously, it provides a uniform basis to assess the reproducibility of works based on this toolbox, including those cited here [1-6]. The referenced works contain a great deal more detail regarding the specific algorithms implemented here, whereas this paper will present a short overview of the PulsatioMech Toolbox

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation

There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown. Prp5 protein (Prp5p) is an RNA-stimulated adenosine triphosphatase (ATPase) required for prespliceosome formation in yeast. We demonstrate through in vivo RNA labeling that, in addition to a splicing defect, the prp5-1 mutation causes a defect in the transcription of intron-containing genes. We present chromatin immunoprecipitation evidence for a transcriptional elongation defect in which RNA polymerase that is phosphorylated at Ser5 of the largest subunit’s heptad repeat accumulates over introns and that this defect requires Cus2 protein. A similar accumulation of polymerase was observed when prespliceosome formation was blocked by a mutation in U2 snRNA. These results indicate the existence of a transcriptional elongation checkpoint that is associated with prespliceosome formation during cotranscriptional spliceosome assembly. We propose a role for Cus2p as a potential checkpoint factor in transcription

Streptococcus mutans adhesion and releasing of metallic ions in dental alloys

Abstract Aim: To evaluate the adherence of Streptococcus mutans to the surface of the amalgam and copper/aluminum alloy samples and also evaluate the release of metallic ions. Methods: The prepared medium was changed every 72 h and analyzed by atomic absorption spectrophotometer. Samples were removed from the prepared medium at 15, 30, 48 and 60 days. Results: The result shows that ions released were statistically different among all groups, and so were both biofilm and pits formation and the corrosion induced by the S. mutans in both types of samples. SEM observation of the samples immersed in the prepared medium with S. mutans showed adherence of microorganisms on the whole surface, in all groups. Conclusions: The S. mutans adhere to both amalgam and copper/aluminum alloy causing corrosion of those restorations. S. mutans produced a greater ions release in Cu/Al alloy; in amalgam, the ions release was not influenced by exposure to S. mutans

Grain Boundary Phases in NbFeSb Half-Heusler Alloys: A New Avenue to Tune Transport Properties of Thermoelectric Materials

Many thermoelectric materials benefit from complex microstructures. Grain boundaries (GBs) in nanocrystalline thermoelectrics cause desirable reduction in the thermal conductivity by scattering phonons, but often lead to unwanted loss in the electrical conductivity by scattering charge carriers. Therefore, modifying GBs to suppress their electrical resistivity plays a pivotal role in the enhancement of thermoelectric performance, zT. In this work, different characteristics of GB phases in Ti-doped NbFeSb half-Heusler compounds are revealed using a combination of scanning transmission electron microscopy and atom probe tomography. The GB phases adopt a hexagonal close-packed lattice, which is structurally distinct from the half-Heusler grains. Enrichment of Fe is found at GBs in Nb0.95Ti0.05FeSb, but accumulation of Ti dopants at GBs in Nb0.80Ti0.20FeSb, correlating to the bad and good electrical conductivity of the respective GBs. Such resistive to conductive GB phase transition opens up new design space to decouple the intertwined electronic and phononic transport in thermoelectric materials

HIDROPSIA FETAL EM DOIS FILHOTES DA RAÇA BULDOGUE INGLÊS

Fetal hydrops is a congenital anomaly characterized by excessive accumulation of fluids in the extravascular space of the fetus, being called anasarca when excess fluid occurs in a generalized way, causing edema in the subcutaneous tissue. Thus, an exaggerated increase in the size of the fetus is expected, which may result in obstructive dystocia during birth. Bulldog dogs are more susceptible to this disease due to their brachycephalic characteristics; therefore, care should be redoubled during pregnancy, such as using ultrasound to periodically evaluate the fetuses to preserve the health of both pregnant and fetuses. It is worth noting that this disease usually has a reserved to severe prognosis. This present work reports the birth of a 3-year-old female English Bulldog that was admitted at a veterinary clinic in the city of Ourinhos/SP, with approximately 62 days of gestation, as a result of artificial insemination, being in labor for approximately 5 hours. From the physical and ultrasound examinations, it was observed that two of the six fetuses had generalized edema, had no reflexes, and presented reduced and muffled heartbeats. The patient underwent an emergency cesarean section. The hydropic puppies s died after an attempted treatment. Thus, it is concluded that the use of ultrasound should be prioritized not only for diagnosis, but for monitoring pregnancy evolution and fetuses, allowing the visualization of possible hydropic fetuses and scheduling of the cesarean section, which is the most indicated surgical procedure in the presence of this fetal anomaly.A hidropsia fetal é uma anomalia congênita, caracterizada pelo acúmulo excessivo de fluidos no espaço extravascular do feto, sendo denominada anasarca, quando o excesso de fluidos ocorre de forma generalizada, causando edema no tecido subcutâneo. Dessa forma, o aumento exagerado no tamanho do feto é esperado, podendo resultar em uma distocia obstrutiva, durante o parto. Os cães da raça Buldogue são mais susceptíveis a essa enfermidade, devido às características braquicefálicas; portanto, deve-se redobrar os cuidados durante a gestação, como utilizar a ultrassonografia para avaliar periodicamente os fetos, com o objetivo de preservar a saúde, tanto da gestante, quanto dos fetos. Vale evidenciar que, geralmente, essa enfermidade possui prognóstico de reservado a grave. Este presente trabalho relata o parto de uma cadela de 3 anos de idade, da raça Buldogue Inglês, que deu entrada em uma clínica veterinária, na cidade de Ourinhos/SP, com aproximadamente 62 dias de gestação, fruto de inseminação artificial, estando em trabalho de parto há aproximadamente 5 horas. A partir da realização dos exames físico e ultrassonográfico, foi observado que dois dos seis fetos apresentavam edema generalizado, estavam sem reflexos e com batimentos cardíacos diminuídos e abafados. A paciente foi submetida a cesariana de emergências filhotes hidrópicos vieram a óbito, após tentativa de tratamento. Diante do exposto, conclui-se que a utilização da ultrassonografia deve ser priorizada, não apenas para diagnóstico, mas para acompanhamento da evolução da gestação e dos fetos, permitindo a visibilização de possíveis fetos hidrópicos e o agendamento da cesariana, procedimento cirúrgico mais indicado na presença dessa anomalia fetal