Mishle Ezopus (Aesop's Fables: Hebrew)

Forty-six fables on a total of 55 pages, with about thirty-five small illustrations, apparently taken from an early source, rendered in green. The illustrations are finely rendered. At first I thought they might be from Bernard Salomon. I spent considerable time checking to see where these illustrations come from, but have not established the source. The spine of this fragile booklet (5¼" x 8½") is weakening.Language note: HebrewAesop; Translated by Israel Zemor

Understanding cultural stress and mental health among Latinos in the us: probabilistic omnidirectional inference model

Recent evidence suggests that cultural stress might predict Latinos’ mental health outcomes. Yet, how two sources of cultural stress such as discrimination and negative context of reception are related to anxiety and depression is not well understood. This study aimed to investigate the impact of discrimination, negative context of reception, and demographic factors on anxiety and depression levels among 1426 Latino adults in theUnited States. Using two novel online simulators based on Bayesian Belief Networks, we explored how variations in these independent variables influence mental health outcomes. Our findings reveal that discrimination and negative context of reception significantly affect anxiety and depression, with discrimination being a stronger predictor. Generational status also played a key role, with second-generation Latinos experiencing worse mental health compared to the first generation. The item “To what extent do you feel that Americans have something against you?” was identified as the strongest predictor of mental health. Probabilistic machine learning approach allowed for the examination of complex interactions and non-linear relationships, providing deeper insights into the dynamics of cultural stressors and mental health. These findings suggest that addressing discrimination and negative context of reception could be vital for interventions aimed at improving the mental health of Latino populations. The use of online simulation tools in this research offers a novel method for subject-matter experts to explore and understand the intricate relationships between cultural stressors and mental health, potentially informing future prevention strategies

INSIGHTS INTO DISEASES OF HUMAN TELOMERASE FROM DYNAMICAL MODELING

Mutations in the telomerase complex disrupt either nucleic acid binding or catalysis, and are the cause of numerous human diseases. Despite its importance, the structure of the human telomerase complex has not been observed crystallographically, nor are its dynamics understood in detail. Fragments of this complex from Tetrahymena thermophila and Tribolium castaneum have been crystallized. Biochemical probes provide important insight into dynamics. In this work we summarize evidence that the T. castaneum structure is Telomerase Reverse Transcriptase. We use this structure to build a partial model of the human Telomerase complex. The model suggests an explanation for the structural role of several diseaseassociated mutations. We then generate a 3D kinematic trajectory of telomere elongation to illustrate a “typewriter ” mechanism: the RNA template moves to keep the end of the growing telomeric primer in the active site, disengaging after every 6-residue extension to execute a “carriage return ” and go back to its starting position. A hairpin can easily form in the primer, from DNA residues leaving the primer-template duplex. The trajectory is consistent with available experimental evidence. The methodology is extensible to Telomere maintenance has broad implications for human health and longevity. Positive lifestyle changes including exercise and smoking cessation result in increased telomerase activity in the immune system.(1) Cancer cells als

Analisis Kemampuan Berpikir Kritis Siswa dalam Pemecahan Masalah Soal Invers Fungsi Berdasarkan Tahapan Polya

Penelitian ini bertujuan untuk mendeskripsikan kemampuan berpikir kritis siswa dalam menyelesaikan masalah fungsi invers berdasarkan tahapan Polya. Jenis penelitian yang digunakan adalah deskriptif kualitatif, dengan menggunakan 4 sampel. Berdasarkan kategori 1 siswa yang kemampuan tinggi, 2 siswa yang kemampuan sedang, dan 1 siswa yang kemampuan rendah. Teknik pengumpulan data dalam penelitian ini adalah dengan menggunakan tes, wawancara, dan dokumentasi. Berdasarkan hasil analisis data kemampuan berpikir kritis dalam pemecahan masalah berdasarkan tahapan Polya dapat disimpulkan bahwa setiap siswa memiliki kemampuan berpikir kritis yang berbeda dimana (1) siswa yang memiliki kategori kemampuan tinggi berada pada tingkat kemampuan berpikir kritis tinggi karena memenuhi lima indikator berpikir kritis dalam pemecahan masalah berbasis Polya. tahapan; (2) siswa dengan kategori kemampuan sedang memiliki dua kemungkinan tingkat kemampuan berpikir kritis, yaitu kemampuan berpikir kritis sedang dan kemampuan berpikir kritis rendah karena memenuhi 2 sampai 4 indikator berpikir kritis dalam pemecahan masalah berdasarkan tahapan Polya; dan (3) siswa yang memiliki kategori kemampuan rendah berada pada tingkat kemampuan berpikir kritis sangat rendah karena tidak memenuhi indikator berpikir kritis dalam pemecahan masalah berbasis tahap Polya

Work satisfaction, quality of life, and leisure time of neonatology fellows and senior neonatologists in Israel

<p>Abstract</p> <p>Objectives</p> <p>To examine work satisfaction, quality of life, and leisure time of neonatology fellows and senior neonatologists in Israel.</p> <p>Methods</p> <p>A validated questionnaire was delivered during the second half of 2008 to all the neonatology fellows and senior neonatologists in Israel. Descriptive analysis, parametric Student’s <it>t</it>-test, and aparametric Mann Whitney and χ2 tests were conducted.</p> <p>Results</p> <p>Of 114 practicing neonatologists in that period in Israel (including both seniors and fellows), 112 (98.25%) participated in the study. The majority of neonatologists were male (53.2%), married (91.7%), 40–60 years old (69.7%), and studied in Israeli medical schools (62.0%). Most did their pediatric residencies and fellowships in Israel (97.2% and 75.7%, respectively). The average number of night/on-call shifts of fellows and senior neonatologists was 8.8 per month (SD ± 3.425) and the number of active on-call shifts was 4.04 (SD ± 3.194). The satisfaction level of neonatologists in Israeli medical centers with patient care, self-reward, work relations, and quality of life was high, but their satisfaction level with workload, income and prestige, and leisure time was low. The general index of work satisfaction and the general index of indices were both high in relation to the mid-range values. The majority of neonatologists stated that they would choose to practice medicine again. Most of them would encourage medical students to choose the same specialty they had chosen. Only a few neonatologists were contemplating changing their choice of specialty. Most neonatologists want to continue practicing medicine; however, a significant number will not recommend that their children do so.</p> <p>Conclusions</p> <p>The satisfaction level of neonatologists in Israel is high, mainly due to satisfaction with their work. High satisfaction levels promise high quality patient care, as well as high satisfaction levels of patients and their families. However, satisfaction with leisure time was low and it will require greater attention and focused steps to correct this.</p

A 230 GHz MMIC-Based Sideband Separating Receiver

A 230 GHz MMIC-based, cryogenically cooled sideband-separating receiver is presented. Utilizing 30 nm InP HEMT MMICs for the front-end LNA and mixers, the system is cooled to 27 K and operates from 200 GHz to 260 GHz. The system is measured in a cryostat that couples the hot, cold and test signal to the DUT without passing through an optical window, reducing losses in the optical path. An average single-sideband (SSB) noise temperature of 92 K is measured across the band. Sideband rejection ratios are between 10 and 15 dB