1,820 research outputs found
Human Reaction to GenAI Threats: A Perspective of Protection Motivation Theory
Generative AI (GenAI) has instigated notable shifts across diverse sectors. Both academia and industry express concerns about ChatGPT\u27s impact on human interaction. Focusing on users active on Stack Overflow and other platforms within Stack Exchange, this study employs a difference-in-differences method to explore their reactions to the threat posed by GenAI through the lens of protection motivation theory. Analyzing users\u27 answering and questioning behaviors reveals a preference for posing questions and crafting longer texts and titles on platforms facing GenAI threats. Similarly, users contribute more elaborate answers on threatened platforms. However, on Stack Overflow, users generate answers with more innovation to avoid being similar to previous answers and deleted by moderators. Notably, experienced users exhibit a more pronounced response to GenAI threats. This study confirms users\u27 awareness of the threat posed by GenAI and the effectiveness of the ban policy launched by the platform
Noise Suppression for CRP Gathers Based on Self2Self with Dropout
Noise suppression in seismic data processing is a crucial research focus for
enhancing subsequent imaging and reservoir prediction. Deep learning has shown
promise in computer vision and holds significant potential for seismic data
processing. However, supervised learning, which relies on clean labels to train
network prediction models, faces challenges due to the unavailability of clean
labels for seismic exploration data. In contrast, self-supervised learning
substitutes traditional supervised learning with surrogate tasks by different
auxiliary means, exploiting internal input data information. Inspired by
Self2Self with Dropout, this paper presents a self-supervised learning-based
noise suppression method called Self-Supervised Deep Convolutional Networks
(SSDCN), specifically designed for Common Reflection Point (CRP) gathers. We
utilize pairs of Bernoulli-sampled instances of the input noisy image as
surrogate tasks to leverage its inherent structure. Furthermore, SSDCN
incorporates geological knowledge through the normal moveout correction
technique, which capitalizes on the approximately horizontal behavior and
strong self-similarity observed in useful signal events within CRP gathers. By
exploiting the discrepancy in self-similarity between the useful signals and
noise in CRP gathers, SSDCN effectively extracts self-similarity features
during training iterations, prioritizing the extraction of useful signals to
achieve noise suppression. Experimental results on synthetic and actual CRP
gathers demonstrate that SSDCN achieves high-fidelity noise suppression
Genotype-Phenotype Correlation in NF1: Evidence for a More Severe Phenotype Associated with Missense Mutations Affecting NF1 Codons 844–848
Neurofibromatosis type 1 (NF1), a common genetic disorder with a birth incidence of 1:2,000–3,000, is characterized by a highly variable clinical presentation. To date, only two clinically relevant intragenic genotype-phenotype correlations have been reported for NF1 missense mutations affecting p.Arg1809 and a single amino acid deletion p.Met922del. Both variants predispose to a distinct mild NF1 phenotype with neither externally visible cutaneous/plexiform neurofibromas nor other tumors. Here, we report 162 individuals (129 unrelated probands and 33 affected relatives) heterozygous for a constitutional missense mutation affecting one of five neighboring NF1 codons—Leu844, Cys845, Ala846, Leu847, and Gly848—located in the cysteine-serine-rich domain (CSRD). Collectively, these recurrent missense mutations affect ∼0.8% of unrelated NF1 mutation-positive probands in the University of Alabama at Birmingham (UAB) cohort. Major superficial plexiform neurofibromas and symptomatic spinal neurofibromas were more prevalent in these individuals compared with classic NF1-affected cohorts (both p < 0.0001). Nearly half of the individuals had symptomatic or asymptomatic optic pathway gliomas and/or skeletal abnormalities. Additionally, variants in this region seem to confer a high predisposition to develop malignancies compared with the general NF1-affected population (p = 0.0061). Our results demonstrate that these NF1 missense mutations, although located outside the GAP-related domain, may be an important risk factor for a severe presentation. A genotype-phenotype correlation at the NF1 region 844–848 exists and will be valuable in the management and genetic counseling of a significant number of individuals
Nonthermal plasma-assisted catalysis NH3 decomposition for COx-free H2 production : A review
Hydrogen (H2) is recognized as a viable and environmentally friendly energy source, utilized across various domains, from large-scale chemical energy exports to small-scale power generation in remote areas. However, the storage and distribution costs of H2 present significant challenges. Ammonia (NH3) emerges as a carbon-free hydrogen carrier, backed by a robust international transport and storage infrastructure. On-site hydrogen production can be efficiently achieved through NH3 decomposition, predominantly via thermal catalysis. One innovative approach involves plasma technology, which utilizes NH3, alcohols, or hydrocarbons to produce pure hydrogen in plasma reactors. Nonthermal plasma (NTP) in particular, for NH3 decomposition and H2 production, has garnered considerable interest owing to its higher energy efficiency than thermal plasma systems. Furthermore, integrating NTP with catalysis, termed plasma-assisted catalysis, creates a synergistic effect, enhancing NH3 decomposition efficiency for H2 production through improved plasma-catalyst interactions. Consequently, NTP-catalysis holds the potential to revolutionize NH3 conversion and utilisation in the future. To date, there have been limited studies on NTP-assisted catalytic NH3 decomposition. This review article compiles the latest NTP-assisted catalytic NH3 decomposition methodologies for H2 production. It delves into the basics of plasma-assisted NH3 decomposition, including adsorption, desorption, and the synergistic processes during plasma catalysis. Additionally, it examines the impact of NTP on the chemical states and properties of various catalysts and provides a comprehensive analysis of the factors influencing NH3-plasma decomposition
Measurements of the pp → ZZ production cross section and the Z → 4ℓ branching fraction, and constraints on anomalous triple gauge couplings at √s = 13 TeV
Four-lepton production in proton-proton collisions, pp -> (Z/gamma*)(Z/gamma*) -> 4l, where l = e or mu, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 35.9 fb(-1). The ZZ production cross section, sigma(pp -> ZZ) = 17.2 +/- 0.5 (stat) +/- 0.7 (syst) +/- 0.4 (theo) +/- 0.4 (lumi) pb, measured using events with two opposite-sign, same-flavor lepton pairs produced in the mass region 60 4l) = 4.83(-0.22)(+0.23) (stat)(-0.29)(+0.32) (syst) +/- 0.08 (theo) +/- 0.12(lumi) x 10(-6) for events with a four-lepton invariant mass in the range 80 4GeV for all opposite-sign, same-flavor lepton pairs. The results agree with standard model predictions. The invariant mass distribution of the four-lepton system is used to set limits on anomalous ZZZ and ZZ. couplings at 95% confidence level: -0.0012 < f(4)(Z) < 0.0010, -0.0010 < f(5)(Z) < 0.0013, -0.0012 < f(4)(gamma) < 0.0013, -0.0012 < f(5)(gamma) < 0.0013
Influence of PODE1 additive into ethanol-gasoline blends (E10) on fuel properties and phase stability
Polyoxymethylene dimethyl ethers (PODEn, n = 1–8) as an oxygenated fuel are a promising alternative fuel with a high oxygen concentration, a low C:H ratio, and no C–C bonds in their chemical structure. This could lead to smoke-free combustion. In this study, we chose to focus on PODE1 because of its lower cetane number, which makes it more suitable for use in spark ignition (SI) engines. However, its lower boiling point and octane number remain challenges. A low boiling point may lead to high vapour pressure and require storage and handling comparable to gaseous fuels. We investigated the effect of adding PODE1 to gasoline-ethanol blends (E10) on fuel properties, including distillation curve, octane number, phase stability, C/O/H ratio, heat of combustion, kinematic viscosity, and density. Our results showed that the blended fuels of E10 and PODE1 are stable up to 10 % PODE1, and there was no phase separation. Additionally, up to 10 % PODE1 additive had no significant side effect on the fuel properties of E10, particularly boiling point and octane number. Thus, work offers creative points by proposing a new candidate for additive fuel to gasoline-ethanol blends, which contributes to reducing the soot emission of GDI engines
Effect of Sciadonic Acid on Hepatic Lipid Metabolism in Obese Mice Induced by A High-fat Diet
Objective: To investigate the potential beneficial effects of sciadonic acid (SA) on improving obesity induced by a high-fat diet in mice. Methods: Forty-eight male C57BL/6 mice were adaptively fed for one week and then randomly divided into the following groups: Control group (C), positive control group (S), model group (M), low-dose sciadonic acid group (LSA), medium-dose sciadonic acid group (MSA), and high-dose sciadonic acid group (HSA). The modeling process lasted for 16 weeks, and the low and high-dose groups were orally administered different doses of SA solution at a fixed time each day. After the modeling period, potential mechanisms of SA in regulating lipid metabolism in obese mice were explored, including aspects such as blood lipid metabolism, hepatic fat metabolism, hepatic oxidative stress, hepatic lipid synthesis, and expression of metabolism-related genes. Results: The high-dose SA intervention in obese mice significantly decreased the levels of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) in serum, while increasing high-density lipoprotein cholesterol (HDL-C) (P<0.05). It inhibited weight gain, reduced epididymal fat accumulation, and improved liver tissue damage. Additionally, SA significantly increased the activities of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in mice (P<0.05), and significantly reduced the production of oxidative end products MDA (P<0.05), alleviated oxidative stress in vivo, and inhibited lipid synthesis by regulating the expression of genes related to lipid metabolism to improve lipid metabolism. Conclusion: SA could improve lipid metabolism disorders in obese mice by suppressing fat accumulation, alleviate oxidative stress, regulate lipid synthesis and metabolism
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