359 research outputs found

    Execution of Commands Using an AI Engine

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    One embodiment includes a method comprising: training an artificial intelligence (AI) engine with successfully executed prior action data; receiving, by the AI engine, a request to perform an action; identifying, by the AI engine, one or more attributes to execute the action; obtaining, by the AI engine, a confirmation of the one or more attributes; identifying, by the AI engine, a plurality of APIs to perform the action as defined by the one or more attributes; identifying, by the AI engine, a sequence of execution for the plurality of APIs to perform the action; and executing, by the AI engine, the plurality of APIs in sequence according to the sequence of execution to achieve perform the action

    Design and Implementation of Terminal Logistics Distribution System Based on IOS Platform

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    The logistics companies often face inefficient distribution and a multitude of customer complaints on the shopping festival. This paper will find out the existing terminal logistics distribution problems, and put forward some suggestions for improvement according to these problems. Combined with the suggestions, an application for the optimization of terminal logistics distribution based on IOS is designed and developed. The application can mainly be divided into order module, map navigation module and communication module. Couriers login the application, process the orders by using bar code technology and get the best solution of delivery by the map. It can improve the distribution efficiency and customer satisfaction to some extent

    Relationship between physical activities and mental health in older people: a bibliometric analysis

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    ObjectiveTo summarize the general situation and focal points of research on the physical activity and mental health of older people over the past 15 years and provide references for future research.MethodsLiterature published between January 1, 2009, and December 31, 2023, was retrieved from the Web of Science core database. A bibliometric visualization analysis of countries/regions, institutions, authors, keywords, and references was conducted using CiteSpace6.1.R6.ResultsA total of 4,329 articles were included, and the annual number of articles published over the past 15 years showed an upward trend. The articles were primarily from 65 countries/regions and 626 institutions. The most represented country and institution were the USA and the University of Pittsburgh, respectively. Among the authors identified, Schuch and Callow were the most influential. The research focuses on four areas: the psychological effects of physical activity in older people; physical activity intervention approaches to the mental health of older people; physical activity and mental health assessment questionnaires; and the impact of physical activity on multidimensional aging. Research frontiers involve emerging topics such as the assessment and intervention of mental health in older people and the relationship between their physical activity and cognitive function.ConclusionThis study conducted a comprehensive, objective, and visual analysis of publications and revealed the status of relevant studies, trending topics, and trends concerning the physical activity and mental health of older people from 2009 to 2023. We hope that this work will help researchers identify new perspectives on potential collaborators, important topics, and research frontiers

    Bibliometric analysis and knowledge mapping of diabetes mellitus combined with tuberculosis research: trends from 1995 to 2023

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    BackgroundThe synergistic epidemic of diabetes mellitus and tuberculosis (DM-TB) has created a dual disease burden, challenging global health systems with complex pathophysiological interactions and suboptimal treatment outcomes. To decode the evolving research landscape, this study presents the latest comprehensive bibliometric analysis mapping the intellectual architecture of DM-TB research over three decades.MethodsWe systematically analyzed 791 peer-reviewed articles from the Web of Science Core Collection (1995-2023) using CiteSpace, VOSviewer, and Bibliometrix. Advanced metrics including co-citation networks, keyword burst detection, and institutional collaboration patterns were employed to identify paradigm-shifting trends.ResultsThree distinct growth phases were observed: initial stagnation (1995-2007, <10 annual publications), exponential growth (2008-2019), and research diversification (2020-2023). The United States dominated scientific output (27.3% of total publications), while the London School of Hygiene & Tropical Medicine emerged as the central hub for international collaborations (TLS=176). Keyword evolution revealed three transformative phases: (1) Pathomechanistic exploration (1995-2016): Focused on hyperglycemia-immunity interplay and epidemiological surveillance; (2) Translational innovation (2017-2020): Shifted to preclinical models, pharmacokinetic optimization, and multidrug resistance; (3) Precision medicine era (2021-2023): Emerging hotspots in latent TB screening (burst strength=6.82), metformin-mediated immunomodulation, and AI-driven diagnostic biomarkers.ConclusionBeyond delineating historical trajectories, this study identifies critical knowledge gaps in inflammation-resolution mechanisms and insulin resistance pathways, proposing a roadmap for targeted biomarker discovery and global health policy formulation. The constructed knowledge framework empowers strategic resource allocation for combating the DM-TB syndemic

    Antihypertensive Effect of Long-Term Oral Administration of Jellyfish (Rhopilema esculentum) Collagen Peptides on Renovascular Hypertension

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    Antihypertensive effect of long-term oral administration of jellyfish (Rhopilema esculentum) collagen peptides (JCP) on renovascular hypertension rats (RVHs) was evaluated. The systolic blood pressure and diastolic blood pressure of the RVHs were significantly reduced with administration of JCP (p < 0.05), compared with model control group. However, the arterial blood pressure of normal rats showed no significant changes during long-term oral treatment with high dose JCP (p > 0.05). Furthermore, effect of JCP on angiotensin II (Ang II) concentration of plasma had no significance (p > 0.05), but JCP significantly inhibited the Ang II concentration in RVHs’ kidney (p < 0.05). The kidney should be the target site of JCP

    Dietary fiber intake and non-alcoholic fatty liver disease: The mediating role of obesity

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    Background and aimsDietary pattern rich in fiber is negatively associated with the risk of non-alcoholic fatty liver disease (NAFLD). Meanwhile, obesity is a known predisposing factor for NAFLD. Nutrient-focused research can enhance the mechanistic understanding of dietary effects. We thus hypothesized that higher dietary fiber intake was associated with lower risk of NAFLD through the mediating role of obesity.MethodsIn this nationwide cross-sectional study, dietary fiber was surveyed using two 24-h recalls. NAFLD and clinically significant fibrosis (CSF) were determined by vibration-controlled transient elastography. Multivariable logistic and linear regression were applied to investigate the association of dietary fiber with NAFLD, CSF, and liver function parameters. We used counterfactual-based mediation analysis to estimate the direct and indirect effect of dietary fiber on NAFLD.ResultsOf the 3,974 participants, ~36.86% and 7.78% of participants were diagnosed with NAFLD and CSF. Compared with participants among the lowest tertile, the highest tertile of dietary fiber consumption was associated with lower odds of NAFLD (OR = 0.81; 95% CI: 0.66–0.98; Poverall = 0.019). Dietary fiber intake appeared to be linked with lower odds of CSF (ORTertile3vs.Tertile1 = 0.81; 95% CI: 0.58–1.14; Poverall = 0.107). Mediation analysis showed that obesity fully mediated the association of dietary fiber with NAFLD. Dietary fiber was associated with improved hepatic parameters.ConclusionsThe findings indicated that increasing dietary fiber intake could confer a greater benefit to protect against NAFLD. Translating these findings regarding dietary fiber into dietary advice might be an attractive strategy for NAFLD prevention

    ePlace-MS: Electrostatics-Based Placement for Mixed-Size Circuits

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    Abstract—We propose eP lace-MS, an electrostatics based placement algorithm for large-scale mixed-size circuits. ePlace-MS is generalized, flat, analytic and nonlinear. The density modeling method eDensity is extended to handle the mixed-size placement. We conduct detailed analysis on the correctness of the gradient formulation and the numerical solution, as well as the rationale of direct-current removal and the advantages over prior density functions. Nesterov’s method is used as the nonlinear solver, which shows high yet stable performance over mixed-size circuits. The steplength as the inverse of Lipschitz constant of the gradient function, while we develop a back-tracking method to prevent overestimation. An approximated nonlinear preconditioner is developed to minimize the topological and physical differences between large macros and standard cells. Besides, we devise a simulated annealer to legalize the layout of macros and use a second-phase global placement to re-optimize the standard cell layout. All the above innovations are integrated into our mixed-size placement prototype ePlace-MS, which outperforms all the related works in literature with better quality and efficiency. Compared to the leading-edge mixed-size placer NTUplace3 [13], ePlace-MS produces up to 22.98 % and on average 8.22 % shorter wirelength over all the sixteen modern mixed-size (MMS) benchmark circuits with the same runtime. Index Terms—Analytic placement, nonlinear optimization, electrostatic analogy, Poisson’s equation, spectral methods, fas

    Real-time Monitoring for the Next Core-Collapse Supernova in JUNO

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    Core-collapse supernova (CCSN) is one of the most energetic astrophysical events in the Universe. The early and prompt detection of neutrinos before (pre-SN) and during the SN burst is a unique opportunity to realize the multi-messenger observation of the CCSN events. In this work, we describe the monitoring concept and present the sensitivity of the system to the pre-SN and SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is a 20 kton liquid scintillator detector under construction in South China. The real-time monitoring system is designed with both the prompt monitors on the electronic board and online monitors at the data acquisition stage, in order to ensure both the alert speed and alert coverage of progenitor stars. By assuming a false alert rate of 1 per year, this monitoring system can be sensitive to the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos up to about 370 (360) kpc for a progenitor mass of 30MM_{\odot} for the case of normal (inverted) mass ordering. The pointing ability of the CCSN is evaluated by using the accumulated event anisotropy of the inverse beta decay interactions from pre-SN or SN neutrinos, which, along with the early alert, can play important roles for the followup multi-messenger observations of the next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure

    JUNO Sensitivity to Invisible Decay Modes of Neutrons

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    We explore the bound neutrons decay into invisible particles (e.g., n3νn\rightarrow 3 \nu or nn2νnn \rightarrow 2 \nu) in the JUNO liquid scintillator detector. The invisible decay includes two decay modes: ninv n \rightarrow { inv} and nninv nn \rightarrow { inv} . The invisible decays of ss-shell neutrons in 12C^{12}{\rm C} will leave a highly excited residual nucleus. Subsequently, some de-excitation modes of the excited residual nuclei can produce a time- and space-correlated triple coincidence signal in the JUNO detector. Based on a full Monte Carlo simulation informed with the latest available data, we estimate all backgrounds, including inverse beta decay events of the reactor antineutrino νˉe\bar{\nu}_e, natural radioactivity, cosmogenic isotopes and neutral current interactions of atmospheric neutrinos. Pulse shape discrimination and multivariate analysis techniques are employed to further suppress backgrounds. With two years of exposure, JUNO is expected to give an order of magnitude improvement compared to the current best limits. After 10 years of data taking, the JUNO expected sensitivities at a 90% confidence level are τ/B(ninv)>5.0×1031yr\tau/B( n \rightarrow { inv} ) > 5.0 \times 10^{31} \, {\rm yr} and τ/B(nninv)>1.4×1032yr\tau/B( nn \rightarrow { inv} ) > 1.4 \times 10^{32} \, {\rm yr}.Comment: 28 pages, 7 figures, 4 table
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