51,595 research outputs found
Trellis-Coded Non-Orthogonal Multiple Access
In this letter, we propose a trellis-coded non-orthogonal multiple access (NOMA) scheme. The signals for different users are produced by trellis coded modulation (TCM) and then superimposed on different power levels. By interpreting the encoding process via the tensor product of trellises, we introduce a joint detection method based on the Viterbi algorithm. Then, we determine the optimal power allocation between the two users by maximizing the free distance of the tensor product trellis. Finally, we manifest that the trellis-coded NOMA outperforms the uncoded NOMA at high signal-to-noise ratio (SNR)
Catalytic RNA and synthesis of the peptide bond
We are studying whether the L-19 IVS ribozyme from Tetrahymena thermophila can catalyze the formation of the peptide bond when it is supplied with synthetic aminoacyl oligonucleotides. If this reaction works, it could give us some insight into the mechanism of peptide bond formation and the origin of coded protein synthesis. Two short oligoribonucleotides, CCCCC and a protected form of CCCCU were prepared; the former was made by the controlled hydrolysis of Poly(C), and the later by multistep chemical synthesis from the protected monomers. The homopentamer was then aminocylated using C-14 labelled Boc-protected glycine imidazolide. This aminoacylated oligo-nucleotide has now been shown to enter the active site of the L-19 IVS, and aminoacyl transfer, and peptide bond formation reactions are being sought. Our synthesis of CCCCU made us aware of the inadequacy of many of the 2'- hydroxyl protecting groups that are in use today and we therefore designed a new 2'- protecting group that is presently being tested
The Impact of the 2006 Massachusetts Healthcare Reform on Spine Surgery Patient Payer-Mix and Age
OBJECTIVE
Several similarities exist between the Massachusetts health care reform law of 2006 and the Affordable Care Act (ACA). The authors’ prior neurosurgical research showed a decrease in uninsured surgeries without a significant change in surgical volume after the Massachusetts reform. An analysis of the payer-mix status and the age of spine surgery patients, before and after the policy, should provide insight into the future impact of the ACA on spine surgery in the US.
METHODS
Using the Massachusetts State Inpatient Database and spine ICD-9-CM procedure codes, the authors obtained demographic information on patients undergoing spine surgery between 2001 and 2012. Payer-mix status was assigned as Medicare, Medicaid, private insurance, uninsured, or other, which included government-funded programs and workers’ compensation. A comparison of the payer-mix status and patient age, both before and after the policy, was performed. The New York State data were used as a control.
RESULTS
The authors analyzed 81,821 spine surgeries performed in Massachusetts and 248,757 in New York. After 2008, there was a decrease in uninsured and private insurance spine surgeries, with a subsequent increase in the Medicare and “other” categories for Massachusetts. Medicaid case numbers did not change. This correlated to an increase in surgeries performed in the age group of patients 65–84 years old, with a decrease in surgeries for those 18–44 years old. New York showed an increase in all insurance categories and all adult age groups.
CONCLUSIONS
After the Massachusetts reform, spine surgery decreased in private insurance and uninsured categories, with the majority of these surgeries transitioning to Medicare. Moreover, individuals who were younger than 65 years did not show an increase in spine surgeries, despite having greater access to health insurance. In a health care system that requires insurance, the decrease in private insurance is primarily due to an increasing elderly population. The Massachusetts model continues to show that this type of policy is not causing extreme shifts in the payer mix, and suggests that spine surgery will continue to thrive in the current US health care system
Mechanism for current saturation and energy dissipation in graphene transistors
From a combination of careful and detailed theoretical and experimental
studies, we demonstrate that the Boltzmann theory including all scattering
mechanisms gives an excellent account, with no adjustable parameters, of high
electric field transport in single as well as double-oxide graphene
transistors. We further show unambiguously that scattering from the substrate
and superstrate surface optical (SO) phonons governs the high field transport
and heat dissipation over a wide range of experimentally relevant parameters.
Models that neglect SO phonons altogether or treat them in a simple
phenomenological manner are inadequate. We outline possible strategies for
achieving higher current and complete saturation in graphene devices.Comment: revtex, 5 pages, 3 figures, to appear in Phys. Rev. Lett
Experimental implementation of high-fidelity unconventional geometric quantum gates using NMR interferometer
Following a key idea of unconventional geometric quantum computation
developed earlier [Phys. Rev. Lett. 91, 197902 (2003)], here we propose a more
general scheme in such an intriguing way: , where and are respectively the dynamic and
geometric phases accumulated in the quantum gate operation, with as a
constant and being dependent only on the geometric feature of the
operation. More arrestingly, we demonstrate the first experiment to implement a
universal set of such kind of generalized unconventional geometric quantum
gates with high fidelity in an NMR system.Comment: 4 pages, 3 figure
Isogeometric B\'ezier dual mortaring: Refineable higher-order spline dual bases and weakly continuous geometry
In this paper we develop the isogeometric B\'ezier dual mortar method. It is
based on B\'ezier extraction and projection and is applicable to any spline
space which can be represented in B\'ezier form (i.e., NURBS, T-splines,
LR-splines, etc.). The approach weakly enforces the continuity of the solution
at patch interfaces and the error can be adaptively controlled by leveraging
the refineability of the underlying dual spline basis without introducing any
additional degrees of freedom. We also develop weakly continuous geometry as a
particular application of isogeometric B\'ezier dual mortaring. Weakly
continuous geometry is a geometry description where the weak continuity
constraints are built into properly modified B\'ezier extraction operators. As
a result, multi-patch models can be processed in a solver directly without
having to employ a mortaring solution strategy. We demonstrate the utility of
the approach on several challenging benchmark problems. Keywords: Mortar
methods, Isogeometric analysis, B\'ezier extraction, B\'ezier projectio
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