2,062 research outputs found

    The Renewed City. New Settlement Principles for the "Re-Construction" of the Urban Form in the Disused Areas

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    The paper will deal with the theme of "re-construction" of the urban form in the areas made available by the industrial, military or infrastructural dismantling processes. Assumed as a "resource" for the contemporary city (often for their "strategic" position), these areas offer the opportunity to focus and experiment new settlement principles capable not only to resolve (on the morphological, spatial and functional level) the relation between the parts of city that were previously divided but, above all, to combine the compact and continuous condition of the city with the presence of wide empty spaces of "nature", intentionally re-introduced into the new urban context. Accepting the challenge of re-building our cities in order to make them corresponding to the aspirations of our time (sustainability, livability, well-being), our research proposes an alternative response to the current settlement "practices". Against the principles of "dispersion", that means the "pervasive" occupation of the urban and suburban soil and the indifference to the peculiarities of the places, it proposes the principle of "densification" and "compaction" of the built volumes in morphologic units that, besides being evocative of the urban condition, are capable to confer to the empty spaces, inside or between them, the value of public places defined by their reciprocal relation. The purpose of this approach is to subtract the empty space (natural or artificial) to its destiny of residual undefined space between "solitary" buildings, in order to give it a higher value: to contribute to the definition of form of the city of our time

    Learning from Las Vegas: Unions and post-industrial urbanisation

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    Las Vegas is often portrayed as the apogee of postmodern urbanism, but we argue that you cannot understand Las Vegas without understanding the role of unions in the City’s political economy. By focusing on the social relations surrounding workplace, class, and gender we highlight alternative versions of Las Vegas’ history. The Culinary Union, a UNITE HERE local, has introduced new institutional forms and played an active role in the local growth coalition. They have set standards around work intensity, training, and job ladders. Highlighting the ability of the union to affect these issues contributes to a counter-narrative about the City which stresses the agency of labour to actively produce Las Vegas’ cultural and economic landscapes. The postmodern narrative about Las Vegas hides these important lessons. Learning from Las Vegas can transform issues of signs and symbolism to issues of union organising and institutional structures in the post-industrial economy. This is the author accepted manuscript. The final version is available via SAGE at http://usj.sagepub.com/content/early/2014/06/16/0042098014536787

    How Do Fairness Definitions Fare? Examining Public Attitudes Towards Algorithmic Definitions of Fairness

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    What is the best way to define algorithmic fairness? While many definitions of fairness have been proposed in the computer science literature, there is no clear agreement over a particular definition. In this work, we investigate ordinary people's perceptions of three of these fairness definitions. Across two online experiments, we test which definitions people perceive to be the fairest in the context of loan decisions, and whether fairness perceptions change with the addition of sensitive information (i.e., race of the loan applicants). Overall, one definition (calibrated fairness) tends to be more preferred than the others, and the results also provide support for the principle of affirmative action.Comment: To appear at AI Ethics and Society (AIES) 201

    Vaccine-induced skewing of T cell responses protects against Chikungunya virus disease

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    Chikungunya virus (CHIKV) infections can cause severe and debilitating joint and muscular pain that can be long lasting. Current CHIKV vaccines under development rely on the generation of neutralizing antibodies for protection; however, the role of T cells in controlling CHIKV infection and disease is still unclear. Using an overlapping peptide library, we identified the CHIKV-specific T cell receptor epitopes recognized in C57BL/6 infected mice at 7 and 14 days post-infection. A fusion protein containing peptides 451, 416, a small region of nsP4, peptide 47, and an HA tag (CHKVf5) was expressed using adenovirus and cytomegalovirus-vectored vaccines. Mice vaccinated with CHKVf5 elicited robust T cell responses to higher levels than normally observed following CHIKV infection, but the vaccine vectors did not elicit neutralizing antibodies. CHKVf5-vaccinated mice had significantly reduced infectious viral load when challenged by intramuscular CHIKV injection. Depletion of both CD

    Association Between Residential Greenness and Cardiovascular Disease Risk

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    Background Exposure to green vegetation has been linked to positive health, but the pathophysiological processes affected by exposure to vegetation remain unclear. To study the relationship between greenness and cardiovascular disease, we examined the association between residential greenness and biomarkers of cardiovascular injury and disease risk in susceptible individuals. Methods and Results In this cross-sectional study of 408 individuals recruited from a preventive cardiology clinic, we measured biomarkers of cardiovascular injury and risk in participant blood and urine. We estimated greenness from satellite-derived normalized difference vegetation index ( NDVI ) in zones with radii of 250 m and 1 km surrounding the participants' residences. We used generalized estimating equations to examine associations between greenness and cardiovascular disease biomarkers. We adjusted for residential clustering, demographic, clinical, and environmental variables. In fully adjusted models, contemporaneous NDVI within 250 m of participant residence was inversely associated with urinary levels of epinephrine (-6.9%; 95% confidence interval, -11.5, -2.0/0.1 NDVI ) and F2-isoprostane (-9.0%; 95% confidence interval, -15.1, -2.5/0.1 NDVI ). We found stronger associations between NDVI and urinary epinephrine in women, those not on β-blockers, and those who had not previously experienced a myocardial infarction. Of the 15 subtypes of circulating angiogenic cells examined, 11 were inversely associated (8.0-15.6% decrease/0.1 NDVI ), whereas 2 were positively associated (37.6-45.8% increase/0.1 NDVI ) with contemporaneous NDVI . Conclusions Independent of age, sex, race, smoking status, neighborhood deprivation, statin use, and roadway exposure, residential greenness is associated with lower levels of sympathetic activation, reduced oxidative stress, and higher angiogenic capacity

    Growing old in England: economic and social issues

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    This paper examines the economic and social impact of changes in the duration of working life for the 80 per cent of older adults living in urban England. While some people are experiencing extended retirement because of moving out of paid work in their fifties, a growing minority of those beyond the state retirement age continue in paid employment. This paper highlights the considerable challenges for urban policy makers in addressing the economic and social inclusion of all older adults
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