Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Acid Dye Dyeability and Finishing Effect of Oak Wood for Indoor Interior Use

Background/Objectives: In this study, we compared and analyzed the dye ability of oak-patterned materials with acid dyes, and evaluated their performance as interior materials. Use of processed timber can help reduce environmental damage and the economic burden of resources (important problems with use of raw timber) and can meet the needs of various fields where the sensibility of raw timber is required. Veneer wood is positioned as a high-value-added product due to its luxury and beauty, and it is used in various fields as a building-related material, such as interior decoration, furniture, flooring, building interior materials, and lumber. Dyeing is necessary to enhance the aesthetic appearance of this pattern and to expand its use.&#x0D; Methods: As the wood used in the experiment, American red oak, which has marketability in the market, was selected. The spectral reflectance of each wavelength band was measured using spectrophotometer to evaluate the apparent concentration and dyeability of the dyed and fixed samples. Durability was evaluated by measuring rubbing and light fastness.&#x0D; Results: The oak pattern was dyed with 3 types of acid dyes and a comparative analysis was performed. The most suitable conditions are 95℃, 3 hours, and 3% o.w.f. In addition, evaluating resilience to daylight fastness, resilience to rubbing, fire resistance, and flame retardance, yielded results suitable for use as an interior material.&#x0D; Conclusion/Implications: It was confirmed that veneer can be dyed with acid dyes and used. It is hoped that this study will be used as basic data for dyeing veneer with acid dyes and synthetic dyes in the future. The results of this research are expected to contribute as basic data for the dyeing process of synthetic dyes.</jats:p