3,727 research outputs found

    Non-perturbative renormalization of overlap quark bilinears on 2+1-flavor domain wall fermion configurations

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    We present renormalization constants of overlap quark bilinear operators on 2+1-flavor domain wall fermion configurations. This setup is being used by the chiQCD collaboration in calculations of physical quantities such as strangeness in the nucleon and the strange and charm quark masses. The scale independent renormalization constant for the axial vector current is computed using the Ward Identity. The renormalization constants for scalar, pseudoscalar and vector current are calculated in the RI-MOM scheme. Results in the MS-bar scheme are also given. The step scaling function of quark masses in the RI-MOM scheme is computed as well. The analysis uses, in total, six different ensembles of three sea quarks each on two lattices with sizes 24^3x64 and 32^3x64 at spacings a=(1.73 GeV)^{-1} and (2.28 GeV)^{-1}, respectively.Comment: 26 pages, 17 figures. More discussions on O(4) breaking effects, and on the perturbative running and a^2p^2 extrapolation of Zs. A subsection for the calculation of the step scaling function of quark mass is added. References added. Version to appear in PR

    Protocol for the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) retrospective study of coronary catheterisation and percutaneous coronary intervention

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    Introduction: During the past decade, the volume of percutaneous coronary intervention (PCI) in China has risen by more than 20-fold. Yet little is known about patterns of care and outcomes across hospitals, regions and time during this period of rising cardiovascular disease and dynamic change in the Chinese healthcare system. Methods and analysis Using the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) research network, the Retrospective Study of Coronary Catheterisation and Percutaneous Coronary Intervention (China PEACE-Retrospective CathPCI Study) will examine a nationally representative sample of 11 900 patients who underwent coronary catheterisation or PCI at 55 Chinese hospitals during 2001, 2006 and 2011. We selected patients and study sites using a two-stage cluster sampling design with simple random sampling stratified within economical-geographical strata. A central coordinating centre will monitor data quality at the stages of case ascertainment, medical record abstraction and data management. We will examine patient characteristics, diagnostic testing patterns, procedural treatments and in-hospital outcomes, including death, complications of treatment and costs of hospitalisation. We will additionally characterise variation in treatments and outcomes by patient characteristics, hospital, region and study year. Ethics and dissemination The China PEACE collaboration is designed to translate research into improved care for patients. The study protocol was approved by the central ethics committee at the China National Center for Cardiovascular Diseases (NCCD) and collaborating hospitals. Findings will be shared with participating hospitals, policymakers and the academic community to promote quality monitoring, quality improvement and the efficient allocation and use of coronary catheterisation and PCI in China. Registration details http://www.clinicaltrials.gov (NCT01624896)

    Observation of χc1\chi_{c1} decays into vector meson pairs ϕϕ\phi\phi, ωω\omega\omega, and ωϕ\omega\phi

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    Decays of χc1\chi_{c1} to vector meson pairs ϕϕ\phi\phi, ωω\omega\omega and ωϕ\omega\phi are observed for the first time using (106±4)×106(106\pm4)\times 10^6 \psip events accumulated at the BESIII detector at the BEPCII e+ee^+e^- collider. The branching fractions are measured to be (4.4±0.3±0.5)×104(4.4\pm 0.3\pm 0.5)\times 10^{-4}, (6.0±0.3±0.7)×104(6.0\pm 0.3\pm 0.7)\times 10^{-4}, and (2.2±0.6±0.2)×105(2.2\pm 0.6\pm 0.2)\times 10^{-5}, for χc1ϕϕ\chi_{c1}\to \phi\phi, ωω\omega\omega, and ωϕ\omega\phi, respectively. The observation of χc1\chi_{c1} decays into a pair of vector mesons ϕϕ\phi\phi, ωω\omega\omega and ωϕ\omega\phi indicates that the hadron helicity selection rule is significantly violated in χcJ\chi_{cJ} decays. In addition, the measurement of χcJωϕ\chi_{cJ}\to \omega\phi gives the rate of doubly OZI-suppressed decay. Branching fractions for χc0\chi_{c0} and χc2\chi_{c2} decays into other vector meson pairs are also measured with improved precision.Comment: 4 pages, 2 figure

    Precision measurement of CPCP violation in Bs0J/ψK+KB_s^0 \to J/\psi K^+K^- decays

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    The time-dependent CPCP asymmetry in Bs0J/ψK+KB_s^0 \to J/\psi K^+K^- decays is measured using pppp collision data, corresponding to an integrated luminosity of 3.03.0fb1^{-1}, collected with the LHCb detector at centre-of-mass energies of 77 and 88TeV. In a sample of 96 000 Bs0J/ψK+KB_s^0 \to J/\psi K^+K^- decays, the CPCP-violating phase ϕs\phi_s is measured, as well as the decay widths ΓL\Gamma_{L} and ΓH\Gamma_{H} of the light and heavy mass eigenstates of the Bs0Bˉs0B_s^0-\bar{B}_s^0 system. The values obtained are ϕs=0.058±0.049±0.006\phi_s = -0.058 \pm 0.049 \pm 0.006 rad, Γs(ΓL+ΓH)/2=0.6603±0.0027±0.0015\Gamma_s \equiv (\Gamma_{L}+\Gamma_{H})/2 = 0.6603 \pm 0.0027 \pm 0.0015ps1^{-1}, andΔΓsΓLΓH=0.0805±0.0091±0.0032\Delta\Gamma_s \equiv \Gamma_{L} - \Gamma_{H} = 0.0805 \pm 0.0091 \pm 0.0032ps1^{-1}, where the first uncertainty is statistical and the second systematic. These are the most precise single measurements of those quantities to date. A combined analysis with Bs0J/ψπ+πB_s^{0} \to J/\psi \pi^+\pi^- decays gives ϕs=0.010±0.039\phi_s = -0.010 \pm 0.039 rad. All measurements are in agreement with the Standard Model predictions. For the first time the phase ϕs\phi_s is measured independently for each polarisation state of the K+KK^+K^- system and shows no evidence for polarisation dependence.Comment: 6 figure

    Analysis and Design of a Magnetically Levitated Planar Motor With Novel Multilayer Windings

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    First evidence of direct CP violation in charmless two-body decays of Bs0 mesons

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    Using a data sample corresponding to an integrated luminosity of 0.35 fb(-1) collected by LHCb in 2011, we report the first evidence of CP violation in the decays of B-s(0) mesons to K-+/-pi(-/+)pairs, A(CP)(B-s(0) -> K pi) = 0.27 +/- 0.08(stat) +/- 0.02(syst), with a significance of 3.3 sigma. Furthermore, we report the most precise measurement of CP violation in the decays of B-0 mesons to K-+/-pi(-/+) pairs, A(CP)(B-0 -> K pi) = -0.088 +/- 0.011(stat) +/- 0.008(syst), with a significance exceeding 6 sigma. RI Galli, Domenico/A-1606-2012; Coca, Cornelia/B-6015-2012; Petrolini, Alessandro/H-3782-2011; Sarti, Alessio/I-2833-2012; Carbone, Angelo/C-8289-2012; manca, giulia/I-9264-2012; de Paula, Leandro/I-9278-2012; Patrignani, Claudia/C-5223-2009; Marconi, Umberto/J-2263-2012; de Simone, Patrizia/J-3549-2012; Cardini, Alessandro/J-5736-2012; Teodorescu, Eliza/K-3044-201

    Measurement of V 0 production ratios in pp collisions at s=0.9 \sqrt {s} = 0.9 and 7 TeV

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    The Λˉ/Λ\bar{\Lambda} / \Lambda and Λˉ/KS0\bar{\Lambda} / K^0_\mathrm{S} production ratios are measured by the LHCb detector from 0.3nb10.3\,\mathrm{nb}^{-1} of pppp collisions delivered by the LHC at s=0.9\sqrt{s} = 0.9\,TeV and 1.8nb11.8\,\mathrm{nb}^{-1} at s=7\sqrt{s} = 7\,TeV. Both ratios are presented as a function of transverse momentum, pTp_\mathrm{T}, and rapidity, yy, in the ranges {0.15<pT<2.50GeV/c0.15 < p_\mathrm{T} < 2.50\,\mathrm{GeV}/c} and {2.0<y<4.52.0<y<4.5}. Results at the two energies are in good agreement as a function of rapidity loss, Δy=ybeamy\Delta y = y_\mathrm{beam} - y, and are consistent with previous measurements. The ratio Λˉ/Λ\bar{\Lambda} / \Lambda, measuring the transport of baryon number from the collision into the detector, is smaller in data than predicted in simulation, particularly at high rapidity. The ratio Λˉ/KS0\bar{\Lambda} / K^0_\mathrm{S}, measuring the baryon-to-meson suppression in strange quark hadronisation, is significantly larger than expected.The Λˉ/Λ\bar{\Lambda} / \Lambda and Λˉ/KS0\bar{\Lambda} / K^0_\mathrm{S} production ratios are measured by the LHCb detector from 0.3nb10.3\,\mathrm{nb}^{-1} of pppp collisions delivered by the LHC at s=0.9\sqrt{s} = 0.9\,TeV and 1.8nb11.8\,\mathrm{nb}^{-1} at s=7\sqrt{s} = 7\,TeV. Both ratios are presented as a function of transverse momentum, pTp_\mathrm{T}, and rapidity, yy, in the ranges {0.15<pT<2.50GeV/c0.15 < p_\mathrm{T} < 2.50\,\mathrm{GeV}/c} and {2.0<y<4.52.0<y<4.5}. Results at the two energies are in good agreement as a function of rapidity loss, Δy=ybeamy\Delta y = y_\mathrm{beam} - y, and are consistent with previous measurements. The ratio Λˉ/Λ\bar{\Lambda} / \Lambda, measuring the transport of baryon number from the collision into the detector, is smaller in data than predicted in simulation, particularly at high rapidity. The ratio Λˉ/KS0\bar{\Lambda} / K^0_\mathrm{S}, measuring the baryon-to-meson suppression in strange quark hadronisation, is significantly larger than expected

    Comparison of anti-EGFR-Fab&amp;rsquo; conjugated immunoliposomes modified with two different conjugation linkers for siRNA delivery in SMMC-7721 cells

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    BACKGROUND: Targeted liposome-polycation-DNA complex (LPD), mainly conjugated with antibodies using functionalized PEG derivatives, is an effective nanovector for systemic delivery of small interference RNA (siRNA). However, there are few studies reporting the effect of different conjugation linkers on LPD for gene silencing. To clarify the influence of antibody conjugation linkers on LPD, we prepared two different immunoliposomes to deliver siRNA in which DSPE-PEG-COOH and DSPE-PEG-MAL, the commonly used PEG derivative linkers, were used to conjugate anti-EGFR Fab’ with the liposome. METHODS: First, 600 μg of anti-EGFR Fab’ was conjugated with 28.35 μL of a micelle solution containing DSPE-PEG-MAL or DSPE-PEG-COOH, and then post inserted into the prepared LPD. Various liposome parameters, including particle size, zeta potential, stability, and encapsulation efficiency were evaluated, and the targeting ability and gene silencing activity of TLPD-FPC (DSPE-PEG-COOH conjugated with Fab’) was compared with that of TLPD-FPM (DSPE-PEG-MAL conjugated with Fab’) in SMMC-7721 hepatocellular carcinoma cells. RESULTS: There was no significant difference in particle size between the two TLPDs, but the zeta potential was significantly different. Further, although there was no significant difference in siRNA encapsulation efficiency, cell viability, or serum stability between TLPD-FPM and TLPD-FPC, cellular uptake of TLPD-FPM was significantly greater than that of TLPD-FPC in EGFR-overexpressing SMMC-7721 cells. The luciferase gene silencing efficiency of TLPD-FPM was approximately three-fold high than that of TLPD-FPC. CONCLUSION: Different conjugation linkers whereby antibodies are conjugated with LPD can affect the physicochemical properties of LPD and antibody conjugation efficiency, thus directly affecting the gene silencing effect of TLPD. Immunoliposomes prepared by DSPE-PEG-MAL conjugation with anti-EGFR Fab’ are more effective than TLPD containing DSPE-PEG-COOH in targeting hepatocellular carcinoma cells for siRNA delivery

    Measurement of the B0→K∗0e+e− branching fraction at low dilepton mass

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    The branching fraction of the rare decay B 0 → K ∗0 e + e − in the dilepton mass region from 30 to 1000 MeV/c 2 has been measured by the LHCb experiment, using pp collision data, corresponding to an integrated luminosity of 1.0 fb−1, at a centre-of-mass energy of 7 TeV. The decay mode B 0 → J/ψ (e + e −)K ∗0 is utilized as a normalization channel. The branching fraction B(B0→K∗0e+e−) is measured to be B(B0→K∗0e+e−)30−1000MeV/c2 =(3.1+0.9−0.8+0.2−0.3±0.2)×10−7, where the first error is statistical, the second is systematic, and the third comes from the uncertainties on the B 0 → J/ψ K ∗0 and J/ψ → e + e − branching fractions
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