1,368 research outputs found
Evidence for at center-of-mass energies from 4.009 to 4.360 GeV
Using data samples collected at center-of-mass energies of =
4.009, 4.230, 4.260, and 4.360 GeV with the BESIII detector operating at the
BEPCII collider, we perform a search for the process
and find evidence for and
with statistical significances of 3.0 and
3.4, respectively. The Born cross sections
, as well as their upper limits at the
90% confidence level are determined at each center-of-mass energy.Comment: 8 pages, 7 figures, 3 table
Improved measurement of the absolute branching fraction of
By analyzing 2.93 fb of data collected at GeV with the
BESIII detector, we measure the absolute branching fraction , which is consistent with previous measurements within
uncertainties but with significantly improved precision. Combining the Particle
Data Group values of , , and the lifetimes of the and
mesons with the value of measured in this work, we determine the following ratios of
partial widths: and .Comment: 9 pages; 8 figure
Accuracy of preimplantation genetic screening (PGS) is compromised by degree of mosaicism of human embryos
Background
To preclude transfer of aneuploid embryos, current preimplantation genetic screening (PGS) usually involves one trophectoderm biopsy at blastocyst stage, assumed to represent embryo ploidy. Whether one such biopsy can correctly assess embryo ploidy has recently, however, been questioned.
Methods
This descriptive study investigated accuracy of PGS in two ways. Part I: Two infertile couples donated 11 embryos, previously diagnosed as aneuploid and, therefore, destined to be discarded. They were dissected into 37 anonymized specimens, and sent to another national laboratory for repeat analyses to assess (i) inter-laboratory congruity and (ii) intra-embryo congruity of multiple embryo biopsies in a single laboratory. Part II: Reports on human IVF cycle outcomes after transfer of allegedly aneuploid embryos into 8 infertile patients.
Results
Only 2/11 (18.2 %) embryos were identically assessed at two PGS laboratories; 4/11 (36.4 %), on repeat analysis were chromosomally normal, 2 mosaic normal/abnormal, and 5/11 (45.5 %) completely differed in reported aneuploidies. In intra-embryo analyses, 5/10 (50 %) differed between biopsy sites. Eight transfers of previously reported aneuploid embryos resulted in 5 chromosomally normal pregnancies, 4 delivered and 1 ongoing. Three patients did not conceive, though 1 among them experienced a chemical pregnancy.
Conclusions
Though populations of both study parts are too small to draw statistically adequately powered conclusions on specific degrees of inaccuracy of PGS, here presented results do raise concerns especially about false-positive diagnoses. While inter-laboratory variations may at least partially be explained by different diagnostic platforms utilized, they cannot explain observed intra-embryo variations, suggesting more frequent trophectoderm mosiaicsm than previously reported. Together with recentl published mouse studies of lineages-specific degrees of survival of aneuploid cells in early stage embryos, these results call into question the biological basis of PGS, based on the assumption that a single trophectoderm biopsy can reliably determine embryo ploidy
Study of e+e−→2(pp¯) at center-of-mass energies between 4.0 and 4.6 GeV
Using data taken at 23 center-of-mass energies between 4.0 and 4.6 GeV with the BESIII detector at the Beijing Electron Positron Collider and with a total integrated luminosity of approximately 15 fb-1, the process e+e-→2(pp¯) is studied for the first time. The Born cross sections for e+e-→2(pp¯) are measured, and no significant structure is observed in the lineshape. The baryon pair (pp and p¯p¯) invariant mass spectra are consistent with phase space, therefore no hexaquark or di-baryon state is found
Observation of a Near-Threshold Structure in the K+ Recoil-Mass Spectra in e+e−→K+(D−sD*0+D*− sD0)
We report a study of the processes of e+e− →K+D− sD*0 and K+D*−sD0 based on e+e− annihilation samples collected with the BESIII detector operating at BEPCII at five center-of-mass energies ranging from 4.628 to 4.698 GeV with a total integrated luminosity of 3.7 fb−1. An excess of events over the known contributions of the conventional charmed mesons is observed near the D−sD*0 and D*−sD0 mass thresholds in the K+ recoil-mass spectrum for events collected at √s =4.681 GeV. The structure matches a mass-dependent-width Breit-Wigner line shape, whose pole mass and width are determined as (3982.5+1.8 −2.6±2.1) MeV/c2 and (12.8+5.3 −4.4 ±3.0) MeV, respectively. The first uncertainties are statistical and the second are systematic. The significance of the resonance hypothesis is estimated to be 5.3 σ over the contributions only from the conventional charmed mesons. This is the first candidate for a charged hidden-charm tetraquark with strangeness, decaying into D− sD*0 and D*− sD0. However, the properties of the excess need further exploration with more statistics
Amplitude analysis and branching fraction measurement of the decay
Using a data set corresponding to an integrated luminosity of 6.32~ recorded by the BESIII detector at center-of-mass energies between
4.178 and 4.226~GeV, an amplitude analysis of the decay is performed, and the relative fractions and phases of
different intermediate processes are determined. The absolute branching
fraction of the decay is measured to be
. The absolute branching
fraction of the intermediate process is determined to be
Antiproton Flux, Antiproton-to-Proton Flux Ratio, and Properties of Elementary Particle Fluxes in Primary Cosmic Rays Measured with the Alpha Magnetic Spectrometer on the International Space Station
International audienceA precision measurement by AMS of the antiproton flux and the antiproton-to-proton flux ratio inprimary cosmic rays in the absolute rigidity range from 1 to 450 GV is presented based on 3.49 × 105antiproton events and 2.42 × 109 proton events. The fluxes and flux ratios of charged elementary particlesin cosmic rays are also presented. In the absolute rigidity range ∼60 to ∼500 GV, the antiproton ¯p, protonp, and positron eþ fluxes are found to have nearly identical rigidity dependence and the electron e− fluxexhibits a different rigidity dependence. Below 60 GV, the ( ¯ p=p), ( ¯ p=eþ), and (p=eþ) flux ratios eachreaches a maximum. From ∼60 to ∼500 GV, the ( ¯ p=p), ( ¯ p=eþ), and (p=eþ) flux ratios show no rigiditydependence. These are new observations of the properties of elementary particles in the cosmos
Amplitude analysis and branching fraction measurement of Ds+→K−K+π+π0
The first amplitude analysis of the decay Ds+→K-K+π+π0 is presented using the data samples, corresponding to an integrated luminosity of 6.32 fb-1, collected with the BESIII detector at e+e- center-of-mass energies between 4.178 and 4.226 GeV. More than 3000 events selected with a purity of 97.5% are used to perform the amplitude analysis, and nine components are found necessary to describe the data. Relative fractions and phases of the intermediate decays are determined. With the detection efficiency estimated by the results of the amplitude analysis, the branching fraction of Ds+→K-K+π+π0 decay is measured to be (5.42±0.10stat±0.17syst)
Cross section measurement of e+e−→pp¯η and e+e−→pp¯ω at center-of-mass energies between 3.773 GeV and 4.6 GeV
Based on 14.7 fb-1 of e+e- annihilation data collected with the BESIII detector at the BEPCII collider at 17 different center-of-mass energies between 3.7730 GeV and 4.5995 GeV, Born cross sections of the two processes e+e-→pp¯η and e+e-→pp¯ω are measured for the first time. No indication of resonant production through a vector state V is observed, and upper limits on the Born cross sections of e+e-→V→pp¯η and e+e-→V→pp¯ω at the 90% confidence level are calculated for a large parameter space in resonance masses and widths. For the current world average parameters of the ψ(4230) of m=4.2187 GeV/c2 and Γ=44 MeV, we find upper limits on resonant production of the pp¯η and pp¯ω final states of 7.5 pb and 10.4 pb at the 90% CL, respectively
Observation of in the amplitude analysis of
We perform for the first time an amplitude analysis of the decay and report the observation of the decay using 2.93 fb of collision data taken
at a center-of-mass energy of 3.773 GeV with the BESIII detector. As the only
W-annihilation free decay among to -pseudoscalar, is the ideal decay to extract the contributions of the
external and internal -emission amplitudes involving and study
the final-state interactions. The absolute branching fraction of is measured to be . The product branching fractions of with and with are measured to be
and , respectively
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