Physical and Geotechnical Perspectives of Gypsum on Lime Stabilized Expansive Soil: A Critical Appraisal

Abstract The gypsum is the source of sulphate commonly found in the soils throughout the world. The expansive soils are considered as problematic soils as they exhibit uncertain swelling and shrinkage in presence of moisture. The expansive soils are treated with different stabilizers to suppress the swelling behaviour. Lime is most effective stabilizer used to stabilize the expansive soil. Researchers reported that expansive soil when treated with lime encounters the gypsum it regenerates the swelling. This regenerated expansion of lime treated soil in presence of sulphate may have alarming signs for sulphate bearing soils. The presence of sulphate alters the mineralogical behaviour of expansive clay. The stabilization additive used f or such soils needs more attention. A comprehensive approach towards proper understanding of the effects of gypsum on lime stabilized soil is required in order to understand the future threats of expansive soils. In this paper, an attempt has been made to present a comprehensive review on the effects of (Gypsum) calcium sulphate dihydrate on the physical properties of untreated and lime treated expansive soil have.</jats:p

Validation of Xgamma Exponential Model via Nikulin-Rao-Robson Goodness-of- Fit-Test under Complete and Censored Sample with Different Methods of Estimation

In this article, a new extension of the one parameter Xgamma distribution has been proposed. Also the associated different statistical properties are derived. The unknown parameter of the proposed distribution is estimated by using different classical estimation methods and by using Bayesian estimation method. Under classical methods of estimation, we brieflfly describe the method of moment estimators, maximum likelihood estimators, maximum product of spacing estimators, least squares and weighted least squares estimators and Cramer-von-Mises estimators. The Bayesian estimation using gamma prior under squared error loss function has been discussed and computed via Lindley’s approximation and Markov Chain Monte Carlo techniques. Furthermore, the 100(1 − α)% asymptotic confifidence interval and credible interval along with the coverage probability are also discussed. The obtained classical and the Bayesian estimators are compared through Monte Carlo simulations. Next, we construct a modifified Chi-squared goodness of fifit test based on the Nikulin-Rao-Robson (NRR) statistic in presence of censored and complete data. The applicability of our proposed model has been illustrated for both complete data and right censored data by using two real data sets for each.</jats:p

A critical review on formulation and evaluation of colon targeted drug delivery systems

A multidisciplinary scientific field that is fast growing is nanotechnology, often known as molecularly generated systems and technologies. Nanotechnology is a rapidly expanding field of applied science and engineering. It relies upon the concept of nano-scale manipulation of matter, meaning the ability to handle materials on a microscopic scale. Nanoparticles can be used to deliver a variety of substances, including conventional drugs, recombinant proteins, vaccines, and more recently nucleotides. Nanoparticles and other colloidal drug delivery techniques change the kinetics, body distribution, and drug release of a related drug. The treatment of negative effects and the distribution of therapy that targets certain tissues or cells are additional effects. As a result, nanoparticles in the pharmaceutical and biotechnology industries boost the therapeutic index and provide solutions to impending delivery problems for new classes of so-called biotech medicines such recombinant proteins and oligonucleotides.</jats:p