Global synchronization control of general delayed discrete-time networks with stochastic coupling and disturbances

Copyright [2008] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.In this paper, the synchronization control problem is considered for two coupled discrete-time complex networks with time delays. The network under investigation is quite general to reflect the reality, where the state delays are allowed to be time varying with given lower and upper bounds, and the stochastic disturbances are assumed to be Brownian motions that affect not only the network coupling but also the overall networks. By utilizing the Lyapunov functional method combined with linear matrix inequality (LMI) techniques, we obtain several sufficient delay-dependent conditions that ensure the coupled networks to be globally exponentially synchronized in the mean square. A control law is designed to synchronize the addressed coupled complex networks in terms of certain LMIs that can be readily solved using the Matlab LMI toolbox. Two numerical examples are presented to show the validity of our theoretical analysis results.This work was supported by the Royal Society Sino-British Fellowship Trust Award of the U.K

Identifying vulnerable children online and what strategies can help them

This new report from UKCCIS’s Evidence Group, Identifying vulnerable children online and what strategies can help them, reveals the latest findings from researchers, clinicians and child protection experts on what makes some children vulnerable on the internet

Global synchronization for discrete-time stochastic complex networks with randomly occurred nonlinearities and mixed time delays

Copyright [2010] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.In this paper, the problem of stochastic synchronization analysis is investigated for a new array of coupled discrete-time stochastic complex networks with randomly occurred nonlinearities (RONs) and time delays. The discrete-time complex networks under consideration are subject to: (1) stochastic nonlinearities that occur according to the Bernoulli distributed white noise sequences; (2) stochastic disturbances that enter the coupling term, the delayed coupling term as well as the overall network; and (3) time delays that include both the discrete and distributed ones. Note that the newly introduced RONs and the multiple stochastic disturbances can better reflect the dynamical behaviors of coupled complex networks whose information transmission process is affected by a noisy environment (e.g., Internet-based control systems). By constructing a novel Lyapunov-like matrix functional, the idea of delay fractioning is applied to deal with the addressed synchronization analysis problem. By employing a combination of the linear matrix inequality (LMI) techniques, the free-weighting matrix method and stochastic analysis theories, several delay-dependent sufficient conditions are obtained which ensure the asymptotic synchronization in the mean square sense for the discrete-time stochastic complex networks with time delays. The criteria derived are characterized in terms of LMIs whose solution can be solved by utilizing the standard numerical software. A simulation example is presented to show the effectiveness and applicability of the proposed results

ADOPT

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Adaptive designs in clinical trials: why use them, and how to run and report them

Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are often more efficient, informative and ethical than trials with a traditional fixed design since they often make better use of resources such as time and money, and might require fewer participants. Adaptive designs can be applied across all phases of clinical research, from early-phase dose escalation to confirmatory trials. The pace of the uptake of adaptive designs in clinical research, however, has remained well behind that of the statistical literature introducing new methods and highlighting their potential advantages. We speculate that one factor contributing to this is that the full range of adaptations available to trial designs, as well as their goals, advantages and limitations, remains unfamiliar to many parts of the clinical community. Additionally, the term adaptive design has been misleadingly used as an all-encompassing label to refer to certain methods that could be deemed controversial or that have been inadequately implemented. We believe that even if the planning and analysis of a trial is undertaken by an expert statistician, it is essential that the investigators understand the implications of using an adaptive design, for example, what the practical challenges are, what can (and cannot) be inferred from the results of such a trial, and how to report and communicate the results. This tutorial paper provides guidance on key aspects of adaptive designs that are relevant to clinical triallists. We explain the basic rationale behind adaptive designs, clarify ambiguous terminology and summarise the utility and pitfalls of adaptive designs. We discuss practical aspects around funding, ethical approval, treatment supply and communication with stakeholders and trial participants. Our focus, however, is on the interpretation and reporting of results from adaptive design trials, which we consider vital for anyone involved in medical research. We emphasise the general principles of transparency and reproducibility and suggest how best to put them into practice

McKillop Library Electricity Use, Impacts and Solutions

A few weeks ago, our class went on a guided tour of the library, which taught us about what goes on in the library, how resources are used, and basically how the library operates. From our tour, we saw many problem areas that could use improvements. One of these areas is the library’s use of electricity. Our group focused on the computers, printers, copiers, lights, and elevators in the library and how the library could use their electricity more efficiently. We have found that the library is not always using electricity effectively and efficiently. There are lights on when nobody is around and there are computers on when students are not using them. Our group examined the library’s electric bill and the electronics that are using up this energy and money. We have discovered that the Library could have the most immediate and far-reaching reduction of greenhouse gas emissions by switching their electricity to GreenStart electricity. We have also found the library could save money and energy by turning electronics off or using power saving options when available

The McKillop Library Waste Stream

The McKillop Library\u27s resources come at an environmental cost because more resources are being used than is realized. The focus is on the amount of carbon emissions and waste that is being produced by the library. Carbon emissions are the leading cause of climate change, and through recycling the library can lower the amount of carbon the library is producing. If recycling and re-using materials becames more of a common procedure in library, there is little doubt that it would be more environmentally friendly

NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS (NIDCD) Comprehensive Strategic Plan and Budget to Reduce and Ultimately Eliminate Health Disparities

It is estimated that one of every six Americans, people of both genders and of all ages and races, experiences some form of communication disorder (e.g., hearing impairment, dizziness, balance problems, smell and taste disorders, and voice, speech or language disturbances). Such disorders often compromise social, emotional, educational and vocational aspects of an individual's life. The cost of these disorders in terms of quality of life and unfulfilled potential is substantial

Psychosocial impact of alternative management policies for low-grade cervical abnormalities : results from the TOMBOLA randomised controlled trial

Background: Large numbers of women who participate in cervical screening require follow-up for minor cytological abnormalities. Little is known about the psychological consequences of alternative management policies for these women. We compared, over 30-months, psychosocial outcomes of two policies: cytological surveillance (repeat cervical cytology tests in primary care) and a hospital-based colposcopy examination. Methods: Women attending for a routine cytology test within the UK NHS Cervical Screening Programmes were eligible to participate. 3399 women, aged 20–59 years, with low-grade abnormal cytology, were randomised to cytological surveillance (six-monthly tests; n = 1703) or initial colposcopy with biopsies and/or subsequent treatment based on colposcopic and histological findings (n = 1696). At 12, 18, 24 and 30-months post-recruitment, women completed the Hospital Anxiety and Depression Scale (HADS). A subgroup (n = 2354) completed the Impact of Event Scale (IES) six weeks after the colposcopy episode or first surveillance cytology test. Primary outcomes were percentages over the entire follow-up period of significant depression (≥8) and significant anxiety (≥11; “30-month percentages”). Secondary outcomes were point prevalences of significant depression, significant anxiety and procedure-related distress (≥9). Outcomes were compared between arms by calculating fully-adjusted odds ratios (ORs) for initial colposcopy versus cytological surveillance. Results: There was no significant difference in 30-month percentages of significant depression (OR = 0.99, 95% CI 0.80–1.21) or anxiety (OR = 0.97, 95% CI 0.81–1.16) between arms. At the six-week assessment, anxiety and distress, but not depression, were significantly less common in the initial colposcopy arm (anxiety: 7.9% vs 13.4%; OR = 0.55, 95% CI 0.38–0.81; distress: 30.6% vs 39.3%, OR = 0.67 95% CI 0.54–0.84). Neither anxiety nor depression differed between arms at subsequent time-points. Conclusions: There was no difference in the longer-term psychosocial impact of management policies based on cytological surveillance or initial colposcopy. Policy-makers, clinicians, and women themselves can be reassured that neither management policy has a significantly greater psychosocial cost