2,997 research outputs found

    Model of large scale man-machine systems with an application to vessel traffic control

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    Mathematical models are discussed to deal with complex large-scale man-machine systems such as vessel (air, road) traffic and process control systems. Only interrelationships between subsystems are assumed. Each subsystem is controlled by a corresponding human operator (HO). Because of the interaction between subsystems, the HO has to estimate the state of all relevant subsystems and the relationships between them, based on which he can decide and react. This nonlinear filter problem is solved by means of both a linearized Kalman filter and an extended Kalman filter (in case state references are unknown and have to be estimated). The general model structure is applied to the concrete problem of vessel traffic control. In addition to the control of each ship, this involves collision avoidance between ship

    Mediterranean ocean Forecasting System: Toward Environmental Predictions-MFSTEP Executive Summary

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    Objectives: The Project aims at the further development of an operational forecasting system for the Mediterranean Sea based upon three main components: a) a Real Time-RT Observing system; b) a numerical forecasting system at the basin scale and for the sub-regional/shelf areas; c) the forecast products dissemination/exploitation system. The Observing system component consists of: • a SOOP-VOS system with RT data dissemination and test of new sensors that collect multidisciplinary data; • a moored buoy network (M3A) designed to serve the RT validation of the basin scale models and the calibration of the ecosystem models; • a satellite RT data analysis system using several satellites for sea surface elevation, sea surface temperature and sea surface winds; • a high space-time resolution network of autonomous subsurface profiling floats (Array for Real-Time Geostrophic Oceanography-ARGO); • a basin scale glider autonomous vehicle experiment; The sampling strategy is continuously assessed by the Observing System Simulation Experiment (OSSE) activities and a RT data management and delayed mode archiving system has been organized

    Evaluating soil extraction methods for chemical characterization of ultramafic soils in Kinabalu Park (Malaysia)

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    Soils derived from ultramafic bedrock are known for hosting distinct vegetation types as a consequence of atypical soil chemistries consisting of high trace elements concentrations (Ni, Cr, Co) and exchangeable cation imbalances (high Mg:Ca quotients). Ecological studies use a range of single-stage extraction methods for chemical characterization of such soils in order to be able to interpret plant response, and ultimately to explain plant community composition. Few studies to date have compared different soil extraction methods in relation to tropical ultramafic soils. This study compares eight commonly used extraction methods on a large number of ultramafic soil samples collected from Kinabalu Park (Malaysia). The tested methods were: for trace elements: NH4AC, DTPA, CaCl2, Sr(NO3)2 and Mehlich-3, for exchangeable cations: NH4Ac and silverthiorea, and for plant-available phosphorus: Mehlich-3 and Olsen-P. These single-stage extraction methods were compared and evaluated for predictive power for chemically characterizing soils, interrelatedness and ecological application. The methods were also contrasted with a sequential extraction scheme. Finally, several operational parameters including molar ratio (0.01 and 0.1 M CaCl2, Sr(NO3)2) and pH buffering (DTPA-TEA) were also evaluated. The majority of single-stage extraction methods are highly inter-correlated and predictive power could be improved by including independent soil parameters (pH, CEC, pseudo-total element concentration) in the multivariate regression equation. Ecological interpretation remains difficult because of lack of experimental studies in relation to plant uptake response and potential phytotoxicity effects on tropical native plants from ultramafic soils

    Low dose Naltrexone for induction of remission in inflammatory bowel disease patients

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    Background: Around 30% of patients with inflammatory bowel disease (IBD) are refractory to current IBD drugs or relapse over time. Novel treatments are called for, and low dose Naltrexone (LDN) may provide a safe, easily accessible alternative treatment option for these patients. We investigated the potential of LDN to induce clinical response in therapy refractory IBD patients, and investigated its direct effects on epithelial barrier function. Methods: Patients not in remission and not responding to conventional therapy were offered to initiate LDN as a concomitant treatment. In total 47 IBD patients prescribed LDN were followed prospectively for 12 weeks. Where available, endoscopic remission data, serum and biopsies were collected. Further the effect of Naltrexone on wound healing (scratch assay), cytokine production and endoplasmic reticulum (ER) stress (GRP78 and CHOP western blot analysis, immunohistochemistry) were investigated in HCT116 and CACO2 intestinal epithelial cells, human IBD intestinal organoids and patient samples. Results: Low dose Naltrexone induce

    The 3^3He(e, e'd)p Reaction in qω\omega-constant Kinematics

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    The cross section for the 3^3He(e, e'd)p reaction has been measured as a function of the missing momentum pmp_m in qω\omega -constant kinematics at beam energies of 370 and 576 MeV for values of the three-momentum transfer qq of 412, 504 and 604 \mevc. The L(+TT), T and LT structure functions have been separated for qq = 412 and 504 \mevc. The data are compared to three-body Faddeev calculations, including meson-exchange currents (MEC), and to calculations based on a covariant diagrammatic expansion. The influence of final-state interactions and meson-exchange currents is discussed. The pmp_m-dependence of the data is reasonably well described by all calculations. However, the most advanced Faddeev calculations, which employ the AV18 nucleon-nucleon interaction and include MEC, overestimate the measured cross sections, especially the longitudinal part, and at the larger values of qq. The diagrammatic approach gives a fair description of the cross section, but under(over)estimates the longitudinal (transverse) structure function.Comment: 17 pages, 7 figure
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